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Search Results - zhengrong+cui
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Layered simulation software for optimizing freeze-drying of porous particle beds
Background Freeze-drying is a critical process in pharmaceutical, nutraceutical, and food manufacturing where product stability and preservation are paramount. Despite its widespread use, traditional freeze-drying remains inefficient, requiring long cycle times and high energy input. These limitations become even more pronounced during scale-up, where...
Published: 12/4/2025
|
Inventor(s):
Zhengrong Cui
,
Benjamin Southard
Keywords(s):
Category(s):
Life sciences > Medical technology > TechBio (software innovation in healthcare)
,
Life sciences > Therapeutics > Manufacturing platform
Nanoparticle technology for sustained release of therapeutic agents
This invention describes lipid-based nanoparticles designed for encapsulating and slowly releasing therapeutic agents, such as siRNA, to treat diseases. These nanoparticles enhance drug delivery efficiency and minimize rapid release, improving treatment outcomes and reducing side effects. Background Chronic inflammation-related diseases, such as rheumatoid...
Published: 10/11/2024
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Inventor(s):
Zhengrong Cui
,
Abdulaziz Aldayel
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug delivery
,
Life sciences > Therapeutics > Small molecule
A pharmaceutical compound for targeted cancer therapy using nucleobase analog derivatives with omega-3 fatty acids
The invention describes compounds combining nucleobase analogs with omega-3 fatty acids, enhancing cancer treatment efficacy, particularly for pancreatic cancer. These compounds improve stability and solubility and demonstrate significant anti-cancer activity, offering potential for targeted therapy. Background Pancreatic cancer presents a significant...
Published: 9/27/2024
|
Inventor(s):
Zhengrong Cui
,
Dharmika Lansakara
Keywords(s):
Category(s):
Life sciences > Therapeutics > Small molecule
,
Life sciences > Therapeutics > Biologic