Search Results - zhengrong+cui

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Thin-film freeze-drying technology for nasal and pulmonary drug delivery
Thin-film freeze-drying creates stable, porous dry powders for nasal and lung delivery of sensitive drugs like vaccines and antibodies. This preserves their activity, targets specific respiratory areas, enhances storage, and effectively treats respiratory infections such as COVID-19. Background Respiratory drug delivery is a vital area in pharmaceutical...
Published: 3/28/2025   |   Inventor(s): Zhengrong Cui, Yu-Sheng Yu, Robert Williams, Khaled AboulFotouh
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Formulation
Nanoparticle technology for sustained release of therapeutic agents
This invention describes lipid-based nanoparticles designed for encapsulating and slowly releasing therapeutic agents, such as siRNA, to treat diseases. These nanoparticles enhance drug delivery efficiency and minimize rapid release, improving treatment outcomes and reducing side effects. Background Chronic inflammation-related diseases, such as rheumatoid...
Published: 10/11/2024   |   Inventor(s): Zhengrong Cui, Abdulaziz Aldayel
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Small molecule
A pharmaceutical compound for targeted cancer therapy using nucleobase analog derivatives with omega-3 fatty acids
The invention describes compounds combining nucleobase analogs with omega-3 fatty acids, enhancing cancer treatment efficacy, particularly for pancreatic cancer. These compounds improve stability and solubility and demonstrate significant anti-cancer activity, offering potential for targeted therapy. Background Pancreatic cancer presents a significant...
Published: 9/27/2024   |   Inventor(s): Zhengrong Cui, Dharmika Lansakara
Keywords(s):  
Category(s): Life sciences > Therapeutics > Small molecule, Life sciences > Therapeutics > Biologic
Nanoparticle technology for targeted therapeutic and diagnostic delivery
The invention involves nanoparticles for targeted delivery of therapeutic and diagnostic agents. These nanoparticles accumulate in specific tissues, disintegrate upon stimuli, and release active agents, enhancing treatment specificity and efficacy while minimizing systemic effects. Background Nanoparticles have their potential to revolutionize drug...
Published: 4/14/2025   |   Inventor(s): Zhengrong Cui, Abdulaziz Aldayel
Keywords(s):  
Category(s): Life sciences > Therapeutics