Search Results - christopher+hunter

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Immune Modulator Encoded Lipid Nanoparticle Formulation Improves T Cell Response to Vaccines
Researchers developed an LNP-mRNA-based vaccine that encodes different cytokine mRNAs, as a method to enhance CD8+ T cell responses and memory formation. Problem: Lipid nanoparticles (LNPs) are an emerging technique to deliver mRNA in vivo more efficiently. While recent progress in mRNA technology has allowed the rapid development of SARS-COV2 vaccines,...
Published: 7/2/2024   |   Inventor(s): Christopher Hunter, Drew Weissman, Mohamad Alameh, Emily Aunins, Anthony Phan
Keywords(s): Bioengineering, Drug Delivery, Immunology, Immunoncology, Immunotherapy, Infectious Disease, Nanotechnology
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Vaccines
Novel Biologics to Treat T Cell Mediated Inflammatory Disease
Biologic therapeutic approach to modulating T cell inflammatory diseases by expressing isolated or recombinant combinations of WSX-1 or gp130 polypeptide with interacting proteins (such as p28, EBI3, Il-27) to inhibit pathological T cell development. Problem: The interleukin-27 receptor (WSX -1) is a heterodimeric type I cytokine receptor for...
Published: 7/3/2024   |   Inventor(s): Christopher Hunter
Keywords(s):  
Category(s): Technology Classifications > Therapeutics