Search Results - chengyue+wu

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Predicting breast cancer response to therapy with MRI and modeling
Background/problem Neoadjuvant therapy (NAT) for cancer treatment is currently based on generalized population-based data such as receptor status, tumor grade, body surface area, and genetic markers. This approach is inherently limited, as it does not account for the unique spatial and physiological characteristics of individual tumors. Consequently,...
Published: 9/9/2024   |   Inventor(s): Thomas Yankeelov, Angela Jarrett, David Hormuth, Anum Kazerouni, Chengyue Wu, Stephanie Barnes
Keywords(s):  
Category(s): Life sciences > Imaging, Life sciences > Diagnostic
Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation
­Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...
Published: 10/2/2023   |   Inventor(s): Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang
Keywords(s): Drug Discovery, Infectious Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology
ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING
ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording. EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...
Published: 8/17/2023   |   Inventor(s): Ada Poon, Cheng Chen, Joonseok Yang, Hui Wang
Keywords(s): EEG, Neurology, Wearable
Category(s): Technology Classifications > Engineering
Quick, Reversible, Moisture-Activated Adhesive
Activated by water quickly, dry hydrogel film adhesive produces a strong and reversible adhesion. Problem: Adhesives are used in numerous applications in our daily lives. In general, adhesives are either strong but irreversible or weak but reversible. There is a need for stronger and reversible adhesives. One potential solution is a formulation of...
Published: 10/16/2023   |   Inventor(s): Shu Yang, Mingtao Chen, Alexander Tucker, Anand Jagota, Yue Wu
Keywords(s): Hydrogels, Surgery
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Materials
New MRI acquisition and post-processing technique for improved breast cancer diagnosis
New computational imaging platform can improve patient-specific characterization of breast cancerProblemClinicians rely on imaging to direct the path of treatment for breast cancer. The current standards for vascular imaging, MRI and CT, can miss valuable information. Fortunately, there has been a wave of technical progress with digital health technologies....
Published: 11/1/2023   |   Inventor(s): Thomas Yankeelov, Chengyue Wu, David Hormuth, Todd Oliver, Robert Moser, Greg Karczmar, Federico Pineda, Ty Easley, Rina Barber, Boyl Kim, Deepa Sheth, Aytek Oto, Hiroyuki Abe, Milica Medved, Xiaobing Fan, Aritrick Chatterjee, Shiyang Wang
Keywords(s): Cancer, Diagnostics, Imaging, Magnetic resonance imaging, Medical imaging, MRI
Category(s): Computer software > Digital health, Life sciences > Medical technology > TechBio (software innovation in healthcare), Life sciences > Diagnostic
Novel Multi-Omics Aging Clock
­A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...
Published: 3/12/2024   |   Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools
Autonomous Drone for railroad track inspection
Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...
Published: 3/15/2023   |   Inventor(s): Yu Qian, Yi Wang, Chen Chen
Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation
Category(s): Engineering and Physical Sciences
Tetrazole & Coumarin Phosphonate Based Broad-Spectrum Beta-Lactamase Inhibitors
Competitive Advantages Combats bacterial antibiotic resistance to β-Lactamase Effectively inhibits against the different classes of β-Lactamase Enhances effectiveness of current β-lactam antibiotics treatments Summary Our inventors have discovered tetrazole and coumarin phosphonate based compounds can actively inhibit...
Published: 6/27/2024   |   Inventor(s): Yu Chen, Orville Pemberton, Adam Renslo, Priyadarshini Jaishankar
Keywords(s): Infectious Diseases Treatment, Pharmaceuticals
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical
Beta-Lactamase Inhibitor Compositions, Methods of Use, and Methods of Treatment
Competitive Advantages Can restore the efficacy of beta-lactam antibiotics Overcomes antibiotic resistance May help to develop new antibiotic treatment regimens Treats multi-drug resistant organisms Summary Our researchers have developed compositions comprised of a beta-lactamase inhibitor and methods of use to treat various infections and...
Published: 6/27/2024   |   Inventor(s): Adam Renslo, Derek Nichols, Priyadarshini Jaishankar, Yu Chen, Erica Lauterwasser
Keywords(s): Infectious Diseases Treatment, Pharmaceuticals
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical
2015-671 Underground Shafts for Hydrogen Storage
SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...
Published: 7/19/2023   |   Inventor(s): Adrienne Lavine, Hossein Kavehpour, Dante Simonetti, Richard Wirz, Chen Chen, Gabriela Bran, Gopinath Warrier, Hamarz Aryafar, Jonathon Kennedy, Joshua Jordan, Keith Lovegrove
Keywords(s): Energy & Water
Category(s): Energy & Environment > Energy Generation > Solar, Energy & Environment > Energy Storage
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