Search Results - boyi+zhang

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Conditional FKBP51 Over-expression Transgenic Mouse

Advantages: Created a transgenic mice model that allows researchers to precisely control the expression of human FKBP51. Offers a tailored approach to studying psychiatric disorders, enabling the development of personalized treatments. Enhances the understanding of the molecular mechanisms underlying psychiatric disorders such as depression,...

Published: 11/5/2024 | Inventor(s): Chad Dickey(VA) (DECEASED - See Notes), Laura Blair, Bo Zhang

Keywords(s): Animal Models, Psychiatry / Mental Health

Category(s): Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Therapeutics

Targeted Therapy for Triple-Negative Breast Cancer

Breast cancer is the second leading cause of death in women and is the most common cancer among women worldwide. There are four main breast cancer subtypes, luminal A, luminal B, HER2-positive and triple-negative. Triple-negative breast cancer (TNBC) is highly invasive and has higher rates of metastasis and a worse prognosis. Metastasis of cancer cells...

Published: 9/12/2023 | Inventor(s): Shengxi Chen, Xiaojiang Cui, Yi Zhang, Sidney Hecht

Keywords(s):

Category(s): Life Science (All LS Techs), Advanced Materials/Nanotechnology, Cancer, Cancer Therapeutics, Pharmaceuticals

Photonic FPGA platform to create arbitrary photonic devices by programming the device structure into the platform.

Background The development and design process for electronic integrated circuits is very intensive before a finalized chip design is sent to the chip fab. Most application-specific electronic integrated circuits require a prototyping process that can be accomplished with a field-programmable gate array (FPGA), an electronic circuit which can be reconfigured...

Published: 5/7/2024 | Inventor(s): Jaime Cardenas Gonzalez, Yi Zhang, Marissa Granados-Baez

Keywords(s):

Category(s): Nanotechnology

Imaging Inflammation using PET Radioligands that Target Translocator Protein 18?kDa with High Affinity Regardless of Genotype

This technology includes a group of radioligands that label inflammatory cells specifically, accurately, and across different genotypes and can be detected using Positron Emission Tomography (PET). The radioligands target the Translocator protein 18 kDa (TSPO) receptor which is present on the outer mitochondrial membrane and is involved in the production...

Published: 10/28/2024 | Inventor(s): Robert Innis, Federico Da Settimo, Giorgio Stefancich, Sabrina Taliani, Sabrina Castellano, Claudia Martini, Yi Zhang, Victor Pike

Keywords(s): 18kDa, Emission, Genotype, Human, Listed LPM Fenn as of 4/15/2015, NA1XXX, Positron, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Quantifying/imaging, Radioligands, Regardless, tomography, TSPO, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX

Category(s): TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Neurology, Application > Software / Apps, Application > Diagnostics, Application > Medical Devices, Application > Research Materials

Neutralizing Antibodies to Influenza HA and Their Use and Identification

The effectiveness of current influenza vaccines varies by strain and season, in part because influenza viruses continuously evolve to evade human immune responses. While the majority of seasonal influenza infections cause relatively mild symptoms, each year influenza virus infections result in over 500,000 hospitalizations in the United States and Europe....

Published: 10/28/2024 | Inventor(s): Robert Bailer, Michael Joyce, John Mascola, Peter Kwong, Sarah Andrews, Paul Thomas, Gwo-Yu Chuang, Adam Wheatley, Yi Zhang, James Whittle, Adrian McDermott

Keywords(s): 1, 2, antibodies, DB4XXX, DBXXXX, DC5XXX, DCXXXX, DXXXXX, GROUP, INFLUENZA, Neutralize, That, Their, Viruses, VLXXXX, WJXXXX, WNXXXX, XAXXXX, XKXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease, ResearchProducts > Antibodies, TherapeuticArea > Immunology

Method for 3D Nonlinear Structured Illumination Super-resolution Imaging

Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Yu Li, Han Zhang

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Programmable In-Memory Computing Accelerator for Low-Precision Deep Neural Network Inference

Background In the era of artificial intelligence, various deep neural networks (DNNs), such as multi-layer perceptron, convolutional neural networks, and recurrent neural networks, have emerged and achieved human-level performance in many recognition tasks. These DNNs usually require billions of multiply-and-accumulate (MAC) operations, soliciting...

Published: 2/23/2023 | Inventor(s): Jae-Sun Seo, Shihui Yin, Mingoo Seok, Bo Zhang

Keywords(s): Artificial Intelligence, Circuits, Computational Machine, Electronics, Machine Learning

Category(s): Physical Science, Computing & Information Technology, Intelligence & Security

Method and Apparatus to Eliminate Crosstalk Effect in Semiconductor Devices

Prevent System Damage and Failure in High-Speed Power Semiconductors Important in Electric Vehicles This technique and apparatus can cancel the intrinsic Miller capacitance of MOSFETs, especially SiC MOSFETs, which results in significantly increased switching speed, significantly reduced crosstalk effect, significantly reduced switching power loss,...

Published: 12/1/2021 | Inventor(s): Shuo Wang, Boyi Zhang

Keywords(s):

Category(s): Technology Classifications > Engineering > Electrical

Two-Cored Inductor Reduces Near Magnetic Field Couplings

CM Inductor Design Lessens Near Magnetic Field Radiation while Improving DM Inductance and Reducing DM noiseThis common mode (CM) inductor design both reduces the near magnetic field couplings between components in electronic systems and attenuates differential-mode (DM) noise. Due to the demand for high power density in electronic systems, their components...

Published: 3/1/2022 | Inventor(s): Shuo Wang, Boyi Zhang

Keywords(s): EMI filters, Inductors, Leakage inductance, Magnetic components, Magnetic flux, Near magnetic field, Reluctance

Category(s): Technology Classifications > Engineering > Electrical