Search Results - cardiovascular+treatments

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IgG-Specific Enzymes with Reduced Residual Glycan Hydrolysis
Application Novel enzymes for IgG-specific glycosynthesis. Key Benefits Nearly full glycosylation of IgG antibodies. Improved antibody-mediated effector function properties. No measurable residual hydrolysis activity. Market Summary The global monoclonal antibodies market is experiencing significant growth due to the rising prevalence of chronic...
Published: 4/3/2025   |   Inventor(s): Eric J. Sundberg, Jonathan Du, Tala Azzam
Keywords(s): Antibodies, Cardiovascular Treatments, Immunology and Inflammation Treatments, Oncology Treatments
Category(s): TechPub Algolia > Research Tools
STAR-Echo: Software to Predict Cardiovascular Disease in Chronic Kidney Disease Patients
Application A novel software for prognosis of MACE in chronic kidney disease patients using spatiotemporal analysis and transformer-based radiomics models. Key Benefits Unique interpretable features – identifies novel features based on longitudinal changes in LVW shape (perimeter & sphericity) and texture (intensity variations) over a...
Published: 2/13/2025   |   Inventor(s): Rohan Dhamdhere, Sadeer Al-Kindi, Gourav Modanwal, Anant Madabhushi
Keywords(s): Algorithm, AI, and Machine Learning, Biomarkers, Cardiovascular Treatments, Nephrology Treatments
Category(s): TechPub Algolia > Software
Therapeutic Compounds Inhibiting DUSP5 and DUSP6 for Cardiomyocyte Proliferation and Cardiac Regeneration
Application Therapeutics using siRNAs and small molecules to treat congenital heart defect and myocardial injuries. Key Benefits Reactivates cardiomyocyte (CM) cell replication, allowing regeneration of heart muscle after cardiac injuries. Therapeutic compounds may be administered for transient regeneration/repair of heart muscle after cardiac...
Published: 2/13/2025   |   Inventor(s): Ahsan Husain, Nawazish Naqvi
Keywords(s): Biologics, Cardiovascular Treatments, Repurposed Drug, Small Molecule
Category(s): TechPub Algolia > Therapeutics
Novel Inhibitors of NOX2/ROS
Applications Novel therapeutics for treatment of various inflammatory airway conditions including chronic obstructive pulmonary disease (COPD). Key Benefits NOX2/ROS inhibitors have potential for use in a wide variety of clinical indications. Current treatments are weakly effective or provide only symptomatic relief for inflammatory airway diseases. Technical...
Published: 2/13/2025   |   Inventor(s): Thota Ganesh, John David Lambeth, Susan Smith, Aiming Sun
Keywords(s): Cardiovascular Treatments, Immunology and Inflammation Treatments, Metabolic Disease Treatments, Neurology and Pain Treatments, Respiratory Treatments, Small Molecule
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Inhibitors of MicroRNA-miR712/miR205 for the Treatment of Atherosclerosis and Other Vascular Conditions
Application Antisense oligonucleotide inhibitors of microRNA-miR712/miR205 to prevent or treat atherosclerosis and aortic aneurysm. Key Benefits 80% reduction on the expression of their microRNA targets. Reduces atheroma plaque formation in a mouse model of atherosclerosis. Provides potential non-surgical treatment for aortic aneurysm. Market...
Published: 2/13/2025   |   Inventor(s): Hanjoong Jo, Chanwoo Kim, Sandeep Kumar, Dong ju Son, Haiwei Qiu, Wakako Takabe
Keywords(s): Cardiovascular Treatments, Cell Therapy
Category(s): TechPub Algolia > Therapeutics