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Multifunctional Radical Quenchers for Mitochondrial Diseases

Mitochondrial diseases are a group of disorders associated with dysfunctional mitochondria, often caused by genetic mutations to mitochondrial DNA. Mitochondrial defects are damaging, particularly to tissues with high energy demands such as neural and muscle tissues. Energy effecting defects have been implicated in forms of movement disorders, cardiomyopathy,...

Published: 1/25/2024 | Inventor(s): Sidney Hecht, Omar Khdour, Mohammad Alam, Sriloy Dey, Yana Chen, Arnaud Chevalier

Keywords(s): Alzheimer's Disease, Drug Discovery, Mitochondrial medicine, Neurodegenerative Disorders

Category(s): Life Science (All LS Techs), Pharmaceuticals, Non-Cancer Therapeutics

Safety-Guaranteed Driving Control of Automated Vehicles

Advanced vehicle control systems (e.g., an electronic stability control system) can greatly reduce accident rates and fatality in accidents. Vehicle control systems in automated vehicles (AVs) are able to ensure vehicle safety in many driving scenarios by cooperating with other advanced perception and path planning systems of the AVs. A typical...

Published: 3/14/2023 | Inventor(s): Yan Chen, Yiwen Huang

Keywords(s): Algorithm Development, Automotive, PS-Computing and Information Technology

Category(s): Physical Science, Computing & Information Technology

Transformable UAV with both Coplanar and Omnidirectional Features

Background Industrial and agricultural unmanned aerial vehicles (UAVs) have been widely used for long-distance flight applications such as aerial photography, mapping, package transportation, inspection, and pesticide spraying. Typically, coplanar multirotor UAVs, such as quadcopters and hexacopters are applied to perform these tasks because of their...

Published: 3/7/2023 | Inventor(s): Shi Lu, Yan Chen

Keywords(s):

Category(s): Physical Science, Manufacturing/Construction/Mechanical, Applied Technologies, Imaging

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 3/15/2023 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

2015-671 Underground Shafts for Hydrogen Storage

SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...

Published: 7/19/2023 | Inventor(s): Adrienne Lavine, Hossein Kavehpour, Dante Simonetti, Richard Wirz, Chen Chen, Gabriela Bran, Gopinath Warrier, Hamarz Aryafar, Jonathon Kennedy, Joshua Jordan, Keith Lovegrove

Keywords(s): Energy & Water

Category(s): Energy & Environment > Energy Generation > Solar, Energy & Environment > Energy Storage

PERFORMS

PERFORMS is an educational self-assessment and training scheme for breast screening professionals and has been in use across the UK NHS since 2007.PERFORMS allows radiologists to improve their skill in detecting the earliest signs of cancer, improving patient outcomes.The PERFORMS scheme is for breast screening professionals and the IMPROVE scheme is...

Published: 1/12/2023 | Inventor(s): Alastair Gale, Yan Chen

Keywords(s): Biotechnology, Healthcare, Pharmaceutical, Software

Category(s): Social Sciences