Search Results - xiaohua+zhu

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Targeting mTOR-Related Autophagy Dysfunction to Treat Age-Related Hearing Loss with Rapamycin and Its Derivatives

Advantages: Novel Application of FDA approved drugs, rapamycin and its derivatives, for treating age-related hearing loss (ARHL). Targeting mTOR alleviates oxidative stress and inflammation in the cochlea, enhancing cellular health and resilience to age-related damage. Potential to Reverse or Delay Age-related hearing loss (ARHL) in patients. Summary: Age-related...

Published: 11/5/2024 | Inventor(s): Robert Frisina, Xiaohua Zhu, Bo Ding, Xiaoxia Zhu

Keywords(s): Pharmaceuticals, Therapeutics

Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices

Fine-Tune Cellulose Crystals in Biocomposites

Morphology change from crystalline (I. Pure Cellulose) to amorphous (III. coagulated in water) or semi-crystalline (IV. coagulated in H2O2) Invention Summary: Natural materials such as cellulose or silk can be used in a multitude of applications such as electrolyte batteries, filters, drug delivery systems and scaffolds for tissue engineering....

Published: 10/21/2024 | Inventor(s): David Salas-De La Cruz, Xiao Hu, Stacy Love, David Verrill

Keywords(s): Biomaterials, Chemical and petrochemical industry, Membranes, Nanotechnology

Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials

2018-910 Prediction of Cardiac Arrest Using Continuous Electrocardiogram

SUMMARYUCLA researchers in the Geffen School of Medicine have developed a method to accurately and timely predict cardiac arrest in hospital patients based on a patient’s own data. This method allows for fewer and more relevant alarms that improve the chance of survival from a cardiac arrest episode.BACKGROUNDIn the United States, over 200,000...

Published: 7/19/2023 | Inventor(s): Duc Do, Noel Boyle, Alan Kuo, Xiao Hu

Keywords(s):

Category(s): Software & Algorithms > Digital Health, Medical Devices > Monitoring And Recording Systems, Therapeutics > Cardiovascular

Methods of Modifying Cellulose Crystallinity

The use of biomaterials has grown in recent years as applications in the packaging materials, automotive, construction and the biomedical fields has increased. Cellulose, the most widely available natural polymer on earth has significant potential for use in biomaterial applications because it is renewable, more environmentally friendly and less costly...

Published: 9/27/2024 | Inventor(s): Xiao Hu, David Salas de la Cruz, Stacy Love, David Verrill

Keywords(s): Biomaterials, Biorenewable, Cellulose, Chemistry

Category(s): Engineering > Materials

Neurostimulation Device for the Treatment of Chronic Pain

Chronic pain is a common, complex, and distressing problem that afflicts more than 20 percent (50 million) of the population in the United States and more than 1.9 billion people worldwide. The condition arises from a series of events or injuries, including but not limited to traumatic injury, obesity, congenital disorders, nerve damage and sports injuries....

Published: 11/1/2024 | Inventor(s): Xue Wei, Jeffrey Hettinger, Xiao Hu, Robert Hirsh

Keywords(s): Biocompatible, Inflammation, Neurostimulation, Pain, Polymers, Protein

Category(s): Human Health Care > Medical Devices

Fabrication of Air-spun Mori silk-TiO2 Nanofibers for Filtration Applications

TechnologyThe disclosure provides a method, apparatus, and collection to produce micro and nanofibers from an adjustable concentric nozzle. This technique consists of the extrusion of protein solution into an evaporative atmosphere to product nanofibers. Previous solution blow techniques focus on the use and generation of synthetic polymers. This details...

Published: 3/6/2024 | Inventor(s): Xiao Hu, Xiaoyang Mou

Keywords(s): Extrusion, Fabrics, Filtration, Nanofibers, Nonwovens

Category(s): Engineering > Materials

2005-242 Noninvasive Intracranial Pressure Assessment

Non-invasive Assessment of Intracranial PressureBACKGROUNDIntracranial pressure (ICP) is the pressure exerted by cerebral spinal fluid in the cranium. Elevated ICP can lead to hypertension and respiratory changes, among other things. Established means of measuring ICP rely on invasive, direct procedures that provide access to intracranial space. Despite...

Published: 7/19/2023 | Inventor(s): Xiao Hu, Neil Martin, Valeriy Nenov

Keywords(s): Bioinformatics, Cns, Diagnostic Markers & Platforms, Medical Devices and Materials, Monitoring And Recording Systems

Category(s): Diagnostic Markers, Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics > CNS and Neurology, Software & Algorithms > Bioinformatics

Dicom/Pacs Compression Techniques

SummaryResearchers led by Xiao Hu from the Department of Surgery at UCLA have created a novel and convenient way to compress and query medical images from a PACS system.BackgroundA picture archiving and communication system (PACS) is a medical imaging technology that provides storage, access, and transmission of different types of medical images. PACS...

Published: 7/19/2023 | Inventor(s): Xiao Hu, Farzad Buxey, Vesselin Zlatev, Robert Platt Iii

Keywords(s): All Types, Life Science Research Tools, Medical Imaging, Other, Software

Category(s): Life Science Research Tools, Medical Devices > Medical Imaging, Software & Algorithms > Programs

An innovative and non-invasive method for early detection and diagnosis of skin disorders

BackgroundSkin disease is one of the leading causes of global disease burden, affecting millions worldwide. There are at least 15 categories of skin diseases, with acne, fungal skin disease, and skin and subcutaneous disease being the most prevalent. Skin diseases are not only a detriment to the skin and quality of life, but also spread over time. It...

Published: 3/6/2024 | Inventor(s): Ben Wu, Gina (Ying) Tang, Xiao Hu

Keywords(s): 3D, Diagnosis, Fluorescence, Imaging, Microscopy , Noninvasive, Skin Disease

Category(s): Human Health Care > Biomarkers, Diagnosis and Detection, Research Tools

Solution blow spun protein-based polymer fibers

Published: 3/6/2024 | Inventor(s): Xiao Hu, Dave Jao, Xiaoyang Mou

Keywords(s): Extrusion, Fabrics, Nanofibers, Nonwovens

Category(s): Engineering > Materials