Search Results - sebastien+ourselin

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Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Ultrafast Thin-Film Vapor Deposition Technique

Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...

Published: 11/18/2025 | Inventor(s): Feng Yan, Lin Li

Keywords(s):

Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical

Scribble: Optimised Segmentation of Medical Images through AI

Summary: A semi-automated, artificial-intelligence based, interactive method for selecting a structure in a medical image, that requires only limited input from the users. What Segmentation is used extensively in medical imaging to highlight specific structures (e.g. an organ, a blood vessel or a tumour) and locations that should be...

Published: 11/12/2024 | Inventor(s): Sebastien Ourselin, Tom Vercauteren, Guotai Wang, Wenqi Li, Lucas Fidon

Keywords(s):

Category(s): Software, Diagnostics, Artificial Intelligence

Solid NURBS Parametrisation for Iso-geometric Analysis

Summary: A resolution-free parametrisation of complex 3D structures using Non-Uniform Rational B-Splines (NURBS) to enable next-generation of simulations with iso-geometric analysis. What A method to compactly parametrise 3D solid structures for next-generation finite-element analysis from different input data. The method uses a minimal...

Published: 1/8/2025 | Inventor(s): Jorge Cardoso, Stefano Moriconi, Sebastien Ourselin, Parashkev Nachev

Keywords(s):

Category(s): Platform Technologies, Software

Biological Flow Simulations Using Graphs

Summary: A method for automate high-performance flow characteristics simulations using graph structures. This allows to quantify complex behaviour in large-scale biological networks. What A method to compute flow characteristics from 3D images of biological networks, such as the patient vasculature or airways. The geometrical features are...

Published: 1/8/2025 | Inventor(s): Jorge Cardoso, Stefano Moriconi, Sebastien Ourselin, Parashkev Nachev

Keywords(s):

Category(s): Software, Diagnostics, Platform Technologies

Patient-Specific Brain Networks from BOLD-fMRI

Summary: A method for analysing functional magnetic resonance (fMRI) images to identify brain networks in task and resting-state experiments. What Blood-oxygen-level dependent functional MRI (BOLD-fMRI) measures change in neuronal activity by detecting alterations in brain blood oxygenation. High oxygenation levels are associated with increased...

Published: 11/12/2024 | Inventor(s): Sebastien Ourselin, Michael Hutel

Keywords(s):

Category(s): Software, Diagnostics

Data Transmission via Multimode Fibres for Medical Imaging and Telecommunication

Summary: a cost-effective and reliable data transmission method based on a time-efficient characterisation of multimode fibers, which can be used in several applications, including medical imaging and telecommunication systems. What Multimode fibers (MMFs) are large core optical fibers that are commonly used to transmit information with light in...

Published: 1/22/2025 | Inventor(s): Wenfeng Xia, Sebastien Ourselin, Tianrui Zhao, Tom Vercauteren

Keywords(s):

Category(s): Medical devices, Diagnostics, Software

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 1/9/2026 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

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