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Composite Gels and Methods of their Use in Tissue Repair, Drug Delivery, and as Implants

Abstract: Gel materials, particularly hydrogels, typically lose their mechanical strength and stiffness as they swell. This property limits their use in both biological (e.g., cartilage and ECM repair) and non-biological (e.g., sealant) applications. Innovative materials in both medical and non-medical application areas are sorely needed. Recent innovations...

Published: 4/8/2024 | Inventor(s): Ferenc Horkay, Peter Basser

Keywords(s): Basser, Cartilage, Composite, Drug Delivery, Gel, Horkay, Hydrogels, IMPLANTS, MATRIX, polymer, sealants, Tissue, Tissue Repair

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices, Collaboration Sought > Materials Available, TherapeuticArea > Dermatology

Use of Detector Response Curves to Optimize Settings for Mass Spectrometry

This CDC developed optimization technology allows one to characterize the behavior of the coefficient of variation (CV) for a range of mass spectrometer machine settings. Surface-enhanced laser desorption/ionization (SELDI) and matrix-assisted laser desorption/ionization (MALDI) are used for the early detection of numerous diseases, for example cervical...

Published: 7/25/2024 | Inventor(s): Brian Gurbaxani, Vincent Emanuele

Keywords(s): AA2XXX, AC3XXX, ADXXXX, ASSISTED, CDC Docket Import, CDC Docket Import CDC Prosecuting, CURVES, DESORPTION/IONIZATION, DETECTOR, Laser, Mass, MATRIX, OID-NCEZID-DHCPP, Optimize, RESPONSE, SETTINGS, SPECTROSCOPY, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VFXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WHXXXX, WIXXXX, WMXXXX, XDXXXX, XFXXXX, XHXXXX, XJXXXX, YBXXXX

Rabbit Antisera to Various Matrix, Matricellular, and Other Secreted Proteins

The extracellular matrix (ECM) is composed of a group of proteins that regulate many cellular functions, such as cell shape, adhesion, migration, proliferation, and differentiation. Deregulation of ECM protein production or function contributes to many pathological conditions, including asthma, chronic obstructive pulmonary disease, arthrosclerosis,...

Published: 7/25/2024 | Inventor(s): Larry Fisher

Keywords(s): ANIMAL, Antisera, Human, Listed LPM Maddox as of 4/15/2015, Matricellular, MATRIX, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, proteins, rabbit, RXXXXX, SECRETED, VARIOUS, VAXXXX, VCXXXX, VDXXXX, VGXXXX, VIXXXX, WIXXXX, XAXXXX, XCXXXX, YAXXXX

Category(s): TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, TherapeuticArea > Oncology, ResearchProducts > Antibodies, Application > Research Materials, TherapeuticArea > Immunology, TherapeuticArea > Geriatrics, Application > Diagnostics

Algorithm for Masking Data for Increased Data Confidentiality and Researchers’ Use

Data Masking for Research Usability and Increased Data SecurityThis algorithm provides data masking for sensitive data while maintaining research usability. A major challenge in scientific research is lack of data availability due to privacy concerns. Data breaches are estimated to cost the United States $5.85 million in 2014. Many current techniques...

Published: 10/27/2021 | Inventor(s): Samuel Wu, Shigang Chen

Keywords(s): Data Management or Analysis (Medical), data privacy, matrix, Privacy, statistical analysis

Category(s): Technology Classifications > Others > Security, Technology Classifications > Research Tools > Others, Technology Classifications > Software > Others