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Search Results - than+le
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Real-Time Program-Specific Log Consolidation for Intrusion Detection
Advantages Reduces logs 219× for efficient data storage Performs real-time analysis with zero offline cost Minimizes memory use through subject activity consolidation Maintains high detection accuracy with low alert fatigue Summary Enterprises today are increasingly targeted by Advanced Persistent Threats (APTs), stealthy, long-term attacks...
Published: 5/30/2025
|
Inventor(s):
Yao Liu
,
Xiao Han
,
Zhuo Lu
Keywords(s):
Computer Science
,
Cybersecurity
Category(s):
Technology Classifications > Computer Science > C/S Cybersecurity
,
Technology Classifications > Computer Science > Algorithms
,
Technology Classifications > Computer Science > Computers Software & Information Technology
,
Technology Classifications > Computer Science > Datasets
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
|
Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer
Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases, such as post-stroke cellular...
Published: 5/13/2025
|
Inventor(s):
Li Niu
,
Zhen Huang
,
Yan Han
,
Congzhou Wang
,
Jae Seon Park
Keywords(s):
RNA
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus
,
Campus > University at Albany
High-Yield, High-Stability Overexpression Tag for Bacterial Protein Production
A novel protein purification tag achieves high yields of pure, soluble, full-length recombinant proteins Background: Current protein purification methods rely on solubility-enhancing tags that permit purification with affinity chromatography and subsequent cleavage with specific proteases to extract the target proteins. Researchers have now developed...
Published: 5/13/2025
|
Inventor(s):
Stewart Loh
,
Jeung-hoi Ha
Keywords(s):
TAF
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Research Tools and Reagents
MDCare: AI-Based Real-Time Surgical Blood Loss Quantification System
Advantages Real-time and continuous blood loss estimation Automated and objective, minimizing human error Enhances surgical decision-making Seamlessly integrates into clinical workflows Mobile alerts for timely, remote monitoring Summary Inaccurate blood loss estimation during surgery remains a critical challenge, with traditional visual and...
Published: 5/12/2025
|
Inventor(s):
Phat Huynh
,
Dang Nguyen
,
Trung Le
,
Aaron Muncey
,
Heath Rutledge-Jukes
,
Pallavi Jonnalagadda
,
Sammer Marzouk
,
Tram Le
Keywords(s):
Artificial Intelligence
,
Medical Diagnostics
,
Sensors
Category(s):
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Medical Sensors
,
Technology Classifications > Medical > Surgery
,
Technology Classifications > Data/AI > D/AI Imaging
MDCare: AI-Based Real-Time Surgical Blood Loss Quantification System
Advantages Real-time and continuous blood loss estimation Automated and objective, minimizing human error Enhances surgical decision-making Seamlessly integrates into clinical workflows Mobile alerts for timely, remote monitoring Summary Inaccurate blood loss estimation during surgery remains a critical challenge, with traditional visual and...
Published: 5/12/2025
|
Inventor(s):
Phat Huynh
,
Dang Nguyen
,
Trung Le
,
Aaron Muncey
,
Heath Rutledge-Jukes
,
Pallavi Jonnalagadda
,
Sammer Marzouk
,
Tram Le
Keywords(s):
Artificial Intelligence
,
Medical Diagnostics
,
Sensors
Category(s):
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Medical Sensors
,
Technology Classifications > Medical > Surgery
,
Technology Classifications > Data/AI > D/AI Imaging
Smart IoT System for Longitudinal Real-time Physiological Monitoring of Cancer Patients Undergoing Treatment
Advantages Provides continuous, real-time patient monitoring from home Uses compact, low-cost IoT devices designed specifically for sleep monitoring in cancer patients Enables predictive analysis of sleep apnea using machine learning and longitudinal data Improves comfort and accessibility over traditional in-lab sleep studies Summary Cancer...
Published: 5/9/2025
|
Inventor(s):
Trung Le
,
Quoc Nguyen
Keywords(s):
Artificial Intelligence
,
Wearable Monitoring Equipment
Category(s):
Technology Classifications > Medical > Medical Devices
Highly Accelerated and High-Resolution T1-Weighted MRI
This invention is for an accelerated, high-resolution T1-weighted magnetic resonance imaging (MRI) via modification of the three-dimensional magnetization-prepared rapid gradient echo (3D MP-RAGE) sequence. Through this modification, optimization is achieved by allowing for faster signal collection and shorter acquisition time with generation of optimal...
Published: 3/24/2025
|
Inventor(s):
Silu Han
,
Nan-kuei Chen
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Radiology
,
Technology Classifications > Imaging & Optics > Medical Imaging
,
Technology Classifications > Medical Devices > Diagnostic
,
Technology Classifications > Healthcare Portfolios > Neurology
Deep Learning-Enhanced Chemiluminescence Vertical Flow Assay for High-Sensitivity Cardiac Troponin I Testing (Case No. 2025-128)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering & Bioengineering have developed a novel, high-sensitivity chemiluminescence vertical flow assay for rapid cardiac diagnostics, addressing current challenges in both modern and underserved healthcare settings. Background: Point-of-care (POC) testing is performed...
Published: 5/23/2025
|
Inventor(s):
Aydogan Ozcan
,
Gyeo-Re Han
,
Artem Goncharov
,
Hyouarm Joung
,
Dino Di Carlo
,
Merve Eryilmaz
Keywords(s):
Category(s):
Chemical
,
Chemical > Instrumentation & Analysis
,
Diagnostic Markers
,
Diagnostic Markers > Targets And Assays
,
Electrical
,
Electrical > Imaging
,
Software & Algorithms
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Therapeutics
,
Therapeutics > Cardiovascular
Intervertebral Disc Repair Using a 3D Porous Hybrid Protein Nanoscaffold
Histological analysis of rat intervertebral disc tissue prior to (left) and post injury (center) compared to 6 weeks post treatment (right). Invention Summary: Degeneration of fibrocartilaginous tissues, such as intervertebral discs (IVD), knee menisci, and other tendon-bone junctions, can lead to debilitating pain. IVD degeneration is the...
Published: 4/22/2025
|
Inventor(s):
Ki-Bum Lee
,
Letao Yang
,
Inbo Han
Keywords(s):
Category(s):
Technology Classifications > Nanotechnology
,
Technology Classifications > Physical Sciences & Engineering
,
Technology Classifications > Biomaterials
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