Search Results - huiliang+wang

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RECAST as an enhanced gene delivery system
Background/problem Gene therapy, a promising tool to explore pathogenesis and a powerful weapon to treat diseases at the genomic level, has been making strides in recent years. It has found use in various applications, from cell therapeutics to treating inherited, and neurodegenerative diseases. However, the current methods of gene (“therapy”,...
Published: 7/25/2024   |   Inventor(s): Huiliang Wang, Wenliang Wang, Aaron Tasset
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Formulation
Ultrasound-programmable nanoparticles for targeted drug release
Background/problem Ideally, a drug meant to accurately target specific tissues or cells involved in a disease will do so and achieve an optimal dose and treatment duration. These will yield the intended cellular and physiological response without undue off-target and side effects. And yet, we live with the reality and risks of side effects. Novel...
Published: 8/15/2024   |   Inventor(s): Wenliang Wang, Huiliang Wang, Yanshu Shi, Banglin Chen
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Biomaterials
Two Compartment Model for Detecting the Toxicity of Liver Metabolites
Overview Liver toxicity is a significant reason many new drugs fail in clinical trials. Primary human hepatocytes (PHHs) are the current gold standard for in vitro liver models; however, they have a number of limitations. We have invented an easy-to-use two-compartment device that provides in vitro 3D high-throughput prediction for safety assessments...
Published: 5/20/2024   |   Inventor(s): Kim Boekelheide, Jeffrey Morgan, Blanche Ip, Susan Hall, Hui Li
Keywords(s):  
Category(s): Diagnostics
Sono-optogenetics: A non-invasive optogenetic platform
Problem Optogenetics is the light-dependent control of genetically modified neurons. Neuronal cells that express microbial opsins can transport ions in a light-gated process. Optogenetics has been used to treat disorders including vision loss in humans. Animal studies indicate that optogenetic therapies have applications in neurological disorders including...
Published: 2/2/2024   |   Inventor(s): Huiliang Wang, Wenliang Wang, Kai Wing Tang, Guosong Hong, Xiang Wu
Keywords(s):  
Category(s): Life sciences > Therapeutics
Wearable long-lasting EEG electrodes
­Problem Electroencephalogram (EEG) is a widely used method to monitor brain activity. EEG uses electrodes that detect electrical activity within the brain that provides crucial information about neurological function. Conventional EEG systems with wired electrodes are used in clinical and laboratory settings, limiting utility and long-term monitoring....
Published: 1/3/2024   |   Inventor(s): Huiliang Wang, Ju-Chun (Leon) Hsieh, Hussein Alawieh, Jose del R Millan
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING
ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording. EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...
Published: 8/17/2023   |   Inventor(s): Ada Poon, Cheng Chen, Joonseok Yang, Hui Wang
Keywords(s): EEG, Neurology, Wearable
Category(s): Technology Classifications > Engineering
Lithium selective organogels
Background Lithium (Li) is a highly reactive alkali metal with excellent heat and electrical conductivity properties, making it useful for a variety of industrial applications. Because of Li’s high reactivity, pure elemental Li is not found in nature but is present as a constituent of salts or other compounds found in brines, mineral ores, clays,...
Published: 12/11/2023   |   Inventor(s): Jonathan Sessler, Zachariah Page, Hu Wang
Keywords(s):  
Category(s): Physical sciences > Energy > Batteries/energy storage, Physical sciences > Materials, Physical sciences > Energy > Renewable, Life sciences > Research tools > Tool/assay/screening platform
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Targeting Treatment For ADAM30 In Pathological Cells
Reference #: 01462 The University of South Carolina is offering licensing opportunities for Targeting treatment for ADAM30 in pathological cells Background: The treatment options for vascular malformations include conservative management, drug treatment, interventional radiology, laser therapy, excisional surgery and psychological treatment. However,...
Published: 9/3/2024   |   Inventor(s): Wenbin Tan, Elaine Taine, Hui Wang, Vi Nguyen, Xialing Cao
Keywords(s): a disintegrin and metalloprotease (ADAM), antibody, biomarker, cancer, inhibitor, vascular malformation
Category(s): Health Sciences, Biomedical and Life Sciences
Thiadiazine Kinase Inhibitors
Thank you for your interest in this technology. Please see our technology brief here: https://app.in-part.com/articles/Mk10MZPK7vJj
Published: 7/1/2019   |   Inventor(s): Robert Devita, Andrew Stewart, Avner Schlessinger, Kunal Kumar, Peter Ung, Hui Wang, Hailing Li
Keywords(s):  
Category(s): Therapeutic
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