Search Results - huiliang+wang

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Liquid-phase gas nanotransducers as an ultrasound actuator and imaging reporter
Background Ultrasound imaging and actuation technologies play a critical role in modern medicine, however applications rely heavily on the use of gas-filled agents, such as microbubbles and gas vesicles, which enhance ultrasound contrast and facilitate mechanical effects in biological tissues. The demand for improved imaging resolution, deeper tissue...
Published: 3/12/2026   |   Inventor(s): Huiliang Wang, Wenliang Wang
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Medical technology
Non-invasive sono-optogenetic platform for deep brain neural modulation
Background Neuromodulation technologies such as deep brain stimulation and optogenetics have transformed the treatment of neurological disorders by enabling targeted control of dysfunctional neural circuits, yet their clinical adoption is limited by invasive surgical requirements, off-target effects, poor penetration depth, and lack of cell-type specificity....
Published: 3/11/2026   |   Inventor(s): Huiliang Wang, Wenliang Wang, Ilia Pyatnitskiy
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Therapeutics
Fully Wearable Band for Long-Term Peripheral Ultrasound Neuromodulation in Pain Management
Wearable ultrasound neuromodulation device for peripheral nerve pain relief A wearable ultrasound armband uses a focused piezoelectric transducer and acoustic hydrogel to deliver low-intensity ultrasound pulses to peripheral nerves, noninvasively reducing chronic and neuropathic pain for several hours. Background Peripheral nerve stimulation has...
Published: 3/11/2026   |   Inventor(s): Huiliang Wang, William Barrera, Jinmo Jeong, Thomas Wynn, Xiang Qian, QiLiang Chen, Yaoyao Jia, Yiming Han
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Ultrasound-triggered anesthetic drug delivery for on-demand chronic pain management
A nanoparticle-based ultrasound-responsive drug delivery system for precise, controlled, and targeted therapeutic release This technology uses ultrasound-triggered nanoparticles to deliver local anesthetics precisely and safely for pain management, reducing side effects and opioid risks, with potential for targeted delivery of other drugs in cancer,...
Published: 3/10/2026   |   Inventor(s): Huiliang Wang, Weilong He, Xi Shi, George Bittner, Cathy Yang, Yanxing Wang, Wenliang Wang, Pengyu Ren
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Wearable ultrasound and EEG patch for noninvasive REM sleep enhancement
Background Sleep is essential for emotional regulation, cognitive function, and overall health. Chronic sleep disruption, prevalent among individuals with PTSD, shift workers, and military personnel, affects tens of millions and contributes to serious long-term health consequences. Despite growing awareness, most existing sleep aid technologies fail...
Published: 1/30/2026   |   Inventor(s): Huiliang Wang, Kai Wing Tang, Jinmo Jeong, Mengmeng Yao
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Kirigami-structured wearable EEG system with hair-compatible hydrogel electrodes
Background Electroencephalography (EEG) is essential for monitoring brain activity across clinical, research, and consumer health applications. It plays a central role in diagnosing neurological disorders such as epilepsy and sleep disorders, supporting stroke rehabilitation, and enabling brain-computer interfaces. As demand grows for continuous and...
Published: 1/13/2026   |   Inventor(s): Huiliang Wang, Ju-Chun Hsieh, Mengmeng Yao
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Methods and Sequences for mRNA and Other HIV Vaccine Development
Unique sequences eliciting broadly neutralizing antibodies (bNAbs) against human immunodeficiency virus (HIV) that could be used to develop effective mRNA-based and other types of HIV vaccine. Problem: Despite decades of research, there is currently no vaccine to prevent HIV infection. A major goal of HIV vaccine programs is to generate bNAbs, which...
Published: 8/1/2025   |   Inventor(s): George Shaw, Edward (Ted) Kreider, Beatrice Hahn, Ashwin Skelly, Hui Li, Drew Weissman
Keywords(s): Bioengineering, HIV/AIDS, Immunology, Infectious Disease, Protein/Peptide (Non-Antibody)
Category(s): Technology Classifications > Vaccines
Wearable ultrasound device for long-term neuromodulation
This wearable ultrasound device uses a miniaturized transducer and bio-adhesive hydrogel to non-invasively stimulate the brain for long durations, potentially treating neurological disorders. Background Transcranial focused ultrasound (tFUS) has emerged as a promising non-invasive technique for neuromodulation, offering advantages over existing methods...
Published: 1/13/2026   |   Inventor(s): Huiliang Wang, Kai Wing Tang, Jinmo Jeong, Ju-Chun Hsieh, Mengmeng Yao
Keywords(s):  
Category(s): Life sciences > Medical technology, Life sciences > Biomaterials
RECAST as an enhanced gene delivery system
Background/problem Gene therapy, a promising tool to explore pathogenesis and a powerful weapon to treat diseases at the genomic level, has been making strides in recent years. It has found use in various applications, from cell therapeutics to treating inherited, and neurodegenerative diseases. However, the current methods of gene (“therapy”,...
Published: 1/13/2026   |   Inventor(s): Huiliang Wang, Wenliang Wang, Aaron Tasset
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Formulation
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