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Search Results - technology+classifications+%3e+medical+%3e+pharmaceuticals
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Process for Oxidative Coupling of Nitroalkanes and Organoborons
Advantages Eliminates hazardous, pyrophoric organometallic reagents and toxic, explosive azides for safer manufacturing Runs safely in water under mild conditions, simplifying manufacturing workflows Uses stable, affordable reagents to cut costs and enable broad substrate versatility Speeds up production of key amine building blocks for drug discovery Summary α-Tertiary...
Published: 7/21/2026
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Updated: 7/21/2026
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Inventor(s):
Minsoo Ju
,
Nayoung Kim
Keywords(s):
Agriculture
,
Chemistry and Chemical Engineering
,
Pharmaceuticals
Category(s):
Technology Classifications > Chemistry
,
Technology Classifications > Medical > Pharmaceuticals
Apparatuses and Methods for Synthesizing Compounds
Advantages Delivers critical compounds on demand, overcoming supply chain limits in remote areas. Compact, modular, lightweight design allows fast transport, assembly, and operation anywhere. Shielding and filtration ensure safe operation with manual or automated control options. Synthesizes diverse compounds impossible on Earth, dispensed as...
Published: 7/1/2026
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Updated: 7/1/2026
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Inventor(s):
Jonna Ocampo
,
Daniel Morejon
,
Abraham Sanchez-Rodriguez
,
Stephanie Carey
Keywords(s):
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Medical Devices
ICA‑1S and ζ‑Stat: Selective aPKC Inhibitors for Anti‑Angiogenic Control Neuroblastoma
Advantages Upstream pathway control: Suppresses VEGF‑A by targeting aPKC, a master regulator of angiogenic signaling. Selective, small-molecule mechanism: offers lower immunogenicity and easier development than antibody-based therapies. Combination-therapy ready: upstream angiogenic pathway control enables synergy with existing treatments. Summary Neuroblastoma...
Published: 7/9/2026
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Updated: 2/16/2026
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Inventor(s):
Sloan Breedy
,
Wishrawana Ratnayake
,
Mildred Acevedo-Duncan
Keywords(s):
Cancer Treatment
,
Small Molecules
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Chemistry
,
Technology Classifications > Medical > Oncology
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Nanogel Delivery of Sunitinib Malate for Ocular Neovascularization
Advantages An optimized intravitreal injection Targets neovascularization to treat associated ocular diseases Extended drug release with intravitreal dosing as infrequent as once a month Non-toxic Summary Vascular endothelial growth factor (VEGF) is a protein produced in the body to stimulate the formation of new blood vessels. Anti-VEGF agents...
Published: 6/22/2026
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Updated: 12/9/2025
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Inventor(s):
Vijaykumar Sutariya
,
Priyanka Bhatt
,
Vipul Amin
,
Srinivas Tipparaju
Keywords(s):
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Ophthalmology
SerpinA3N is a Novel Therapeutic Target for Preventing Acute Kidney Injury-Induced Cardiac Fibrosis
Advantages Novel Mechanistic Insight: Identification of SerpinA3N-GZMB axis links AKI to cardiac fibrosis and dysfunction. New Therapeutic Target: targeting SerpinA3N-GZMB axis enables a novel treatment approach for maladaptive cardiac remodeling. Diagnostic and Drug Discovery Potential: SerpinA3N and GZMB could serve as biomarkers for diagnostics...
Published: 7/29/2026
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Updated: 10/31/2025
|
Inventor(s):
Gowda Pramod
,
Ruisheng Liu
Keywords(s):
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Therapeutics
Exogenous Acetate Formulations for Treating Alcohol Use Disorder and Withdrawal
Advantages Mechanistic Innovation: stabilizes brain energy metabolism and modulates adenosine signaling mechanisms not targeted by current addiction therapies. Targeted Brain Delivery: formulations enable effective acetate transport across the blood-brain barrier, (BBB) Controlled and sustained release Versatile Administration Routes: compatible...
Published: 7/13/2026
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Updated: 9/30/2025
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Inventor(s):
Dominic D'Agostino
Keywords(s):
Neuroscience
,
Pharmaceuticals
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Chemistry
,
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Neuroscience
Reversing Heart Failure via Farnesyltransferase Inhibition
Advantages First-in-Class Mechanism: Targets a novel pathway—protein farnesylation—for heart failure treatment. Broad Therapeutic Potential: Effective in both HFrEF and HFpEF, addressing a major unmet need. Tested in multiple preclinical models: Danon disease cardiomyopathy (genetic model); HFpEF (diet-induced and hypertensive models);...
Published: 7/2/2026
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Updated: 9/8/2025
|
Inventor(s):
Kunhua Song
,
Congwu Chi
,
Amanda Conniff
Keywords(s):
Cardiovascular Diseases
,
Drug Repurpose
,
Medical Pharmaceuticals
,
Therapeutics
Category(s):
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Chemistry
A Novel Immunomodulatory Strategy for Treating Heart Failure in Aging Populations
Advantages Novel Mechanism of Action: Targets the Th17/IL17A signaling axis Validated Target: IL17A is already clinically validated in other inflammatory diseases (e.g., psoriasis, psoriatic arthritis), with FDA-approved therapies like secukinumab Strong Preclinical POC: transcriptomic, histological, and functional cardiac assessments showing reversal...
Published: 6/22/2026
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Updated: 8/25/2025
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Inventor(s):
Wanling Xuan
,
Srinivas Tipparaju
Keywords(s):
Cardiological Diseases Treatment
,
Cardiovascular Diseases
,
Drug Discovery
Category(s):
zzCardiology
,
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Therapeutics
Spatiotemporal Drug Control in Autoimmune and Inflammatory Diseases: Photoswitchable JAK2 Inhibitors for Reversible Kinase Modulation
Advantages Precise spatiotemporal control and reversible modulation of kinase activity Reduced systemic toxicity and off-target effects Superior binding affinity and isomer selectivity than traditional Jak 2 inhibitor Summary Janus kinase 2 (JAK2), a key player in hematologic cancers and autoimmune diseases, is a particularly challenging target...
Published: 6/22/2026
|
Updated: 8/18/2025
|
Inventor(s):
Shelby Kell
,
Chavdar Slavov
Keywords(s):
Autoimmune Diseases
,
Inflammatory Diseases
,
Small Molecules
,
Therapeutics
Category(s):
Technology Classifications > Medical > Biomedical Engineering
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Methionine Sulfoxide Reductase A (MsrA) Gene Therapy for Retinal Degeneration
Advantaages Targeted Protection Against Oxidative Stress Dual-Vector Delivery System (AAV and Lenti) Simple and scalable plasmid design for efficient production Suitable for major ophthalmology indications: Age-related macular degeneration (AMD), Retinitis pigmentosa, other oxidative stress-related retinal degenerations Summary Oxidative stress...
Published: 6/22/2026
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Updated: 8/18/2025
|
Inventor(s):
Manas Biswal
Keywords(s):
Ophthalmology
,
Pharmaceuticals
Category(s):
Technology Classifications
,
Technology Classifications > Medical > Biomedical Engineering
,
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
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