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Search Results - sloan+breedy
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ICA‑1S and ζ‑Stat: Selective aPKC Inhibitors for Anti‑Angiogenic Control Neuroblastoma
Advantages Upstream pathway control: Suppresses VEGF‑A by targeting aPKC, a master regulator of angiogenic signaling. Selective, small-molecule mechanism: offers lower immunogenicity and easier development than antibody-based therapies. Combination-therapy ready: upstream angiogenic pathway control enables synergy with existing treatments. Summary Neuroblastoma...
Published: 3/6/2026
|
Updated: 2/16/2026
|
Inventor(s):
Sloan Breedy
,
Wishrawana Ratnayake
,
Mildred Acevedo-Duncan
Keywords(s):
Cancer Treatment
,
Small Molecules
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Chemistry
,
Technology Classifications > Medical > Oncology
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Novel Compounds and Methods for Treating Metastatic Melanoma and Prostate Cancer
Advantages: Precision Targeting: Selective cancer cell targeting minimizes harm to healthy tissues, enhancing safety. Preclinical Efficacy: Induces cancer cell apoptosis, showing promise for treating metastatic melanoma and prostate cancer. Scientific Rigor: Grounded in robust research, offering innovative oncology solutions. Summary: Metastatic...
Published: 7/11/2024
|
Updated: 11/3/2023
|
Inventor(s):
Wishrawana Ratnayake
,
Kirpal Bisht
,
Mildred Acevedo-Duncan
,
Sloan Breedy
,
Aaron Todman
,
Luke Lajmi
Keywords(s):
Cancer Treatment Melanoma
,
Cancer Treatment Prostate Cancer
Category(s):
Technology Classifications > Medical > Biomedical Engineering
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Cancer