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Search Results - kevin+schilling
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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025
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Inventor(s):
Li Li
,
Shichao Wu
,
Jiawei Zhao
Keywords(s):
Category(s):
Technology Category > Research tools
,
Technology Category > Animal models
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Technology Category > Biology
,
Technology Category > Diagnostic
Ultrafast Thin-Film Vapor Deposition Technique
Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...
Published: 11/18/2025
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Inventor(s):
Feng Yan
,
Lin Li
Keywords(s):
Category(s):
Semiconductors, Materials & Processes
,
Microelectronics
,
Physical Science
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Semiconductor Devices
,
Manufacturing/Construction/Mechanical
De novo peptide sequencer
Summary De novo protein-sequencing approaches are poised to revolutionize nearly all fields of biological research and medicine; however current approaches are low-throughput and limited in their sensitivity. The current technology is a novel method that could be implemented with existing reagents and equipment to improve de novo peptide sequencing...
Published: 7/19/2024
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Inventor(s):
Eugene Tu
,
Fehmi Civitci
,
Kevin Schilling
,
Mingchong Dai
,
Nicholas Groves
,
Justin Plaut
,
Srivathsan Ranganathan
,
Andy Mendoza
,
Riccardo Carloni
,
Yu-Jui (Roger) Chiu
,
Emine (Sila) Ozdemir
,
Bruce Branchaud
Keywords(s):
Research Tools
,
Research Tools - Other
Category(s):
Proteomics
,
Research Tools
Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors
Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...
Published: 1/9/2026
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Inventor(s):
Michael Keidar
,
Li Lin
,
Vikas Soni
,
Xiaoliang Yao
,
Dayun Yan
,
Jonathan Sherman
Keywords(s):
Category(s):
Technology Classifications > Medical Devices
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Technology Classifications > Medical Devices > Surgical
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026
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Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Cold atmospheric plasma-stimulated media for treating cancers
For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...
Published: 1/9/2026
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Inventor(s):
Michael Keidar
,
Zhitong Chen
,
Xiaoqian Cheng
,
Li Lin
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Cells
,
Technology Classifications > Therapeutics
Novel Methylation Specific DNA Binding Resins
Cancer is one of the biggest challenges facing the present healthcare community. Cancer diagnostics play a very important role in detecting the onset of disease and enabling continuous monitoring of patients in remission. Early detection of disease occurrence, progression and/or recurrence can significantly increase the chances of patient survival....
Published: 2/13/2025
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Inventor(s):
Kaushal Rege
,
Taraka Sai Pavan Grandhi
,
Sudhakar Godeshala
,
Kevin Lin
Keywords(s):
Category(s):
Bioanalytical Assays, Chemistries & Devices
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Advanced Materials/Nanotechnology
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Life Science (All LS Techs)
,
Genomic Assays/Reagents/Tools
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Diagnostic Assays/Devices
Multilayer Batch Microfabricated Magnetic Shielding
UCLA Case No. 2018-014 SUMMARYUCLA researchers in the Department of Electrical Engineering have developed a novel batch microfabrication technique for microscale shielding layers, simultaneously pushing the limits of minimum size, maximum shielding factor, flexibility, and cost.BACKGROUNDCompact electromagnetic shielding paves the way for a new generation...
Published: 7/17/2025
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Inventor(s):
Robert Candler
,
Jimmy Chen-Yen Wu
,
Ling Li
,
Jere Harrison
Keywords(s):
Electronics & Semiconductors
Category(s):
Electrical > Electronics & Semiconductors
,
Materials > Fabrication Technologies
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
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Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
,
Jacques Albert
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources
Algorithm for improved Spatial Sampling Design of DNAPL contaminants
SUMMARYImproved algorithm that reduces sampling required to monitor the remediation of Dense Nonaqueous Phase Liquid (DNAPL) contaminants in subsurface water.BACKGROUNDThe difficulties encountered in the remediation of Dense Nonaqueous Phase Liquid (DNAPL) contaminants in the subsurface have spawned numerous studies relating to evaluation of the benefits...
Published: 1/15/2025
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Inventor(s):
Linda Abriola
,
Ke Li
Keywords(s):
Category(s):
Software
,
Cleantech
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