Search Results - proteomics

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Summary The current technology is an improved method of antibody conjugation that allows for rapid and scalable antibody labeling, which could be utilized for a number of omics techniques and other antibody-based platforms. Technology Overview In order to label and functionalize antibodies, direct or secondary conjugations are typically employed....

Published: 11/2/2023 | Inventor(s): Kai Tao, Srivathsan Ranganathan, Emine (Sila) Ozdemir, Matthew Rames, Michael Brasino, Mingchong Dai, Gulsu Sener Yildrim

Keywords(s): Research Tools

Category(s): Research Tools, Proteomics

De novo peptide sequencer

Summary De novo protein-sequencing approaches are poised to revolutionize nearly all fields of biological research and medicine; however current approaches are low-throughput and limited in their sensitivity. The current technology is a novel method that could be implemented with existing reagents and equipment to improve de novo peptide sequencing...

Published: 7/19/2024 | Inventor(s): Eugene Tu, Fehmi Civitci, Kevin Schilling, Mingchong Dai, Nicholas Groves, Justin Plaut, Srivathsan Ranganathan, Andy Mendoza, Riccardo Carloni, Yu-Jui (Roger) Chiu, Emine (Sila) Ozdemir, Bruce Branchaud

Keywords(s): Research Tools, Research Tools - Other

Category(s): Proteomics, Research Tools

Neural Network Approach to Matching of Mass Spectral Data

Researchers as TGen have developed methods and algorithms to improve the yield of identifiable protein sequences from mass spectrometry data. Using a Convolutional Neural Network (CNN) approach, proteins, peptides, and other small molecules can be classified and identified from mass spectrometry data with additional confidence in a high throughput...

Published: 8/14/2024 | Inventor(s): Patrick Pirrotte, Gil Speyer, Ritin Sharma, Krystine Garcia-Mansfield

Keywords(s):

Category(s): Proteomics, Computer Methods

Development of a multimolecular and multimodular biomarker panel for the early screening, molecular distinction and clinical follow-up of patients developing preeclampsia/HELLP syndrome and its preparation for preclinical testing

Development of a Multimolecular and Multimodular Biomarker Panel for the Early Screening, Molecular Distinction and Clinical Follow-Up of Patients Developing Preeclampsia/HELLP Syndrome and its Preparation for Preclinical Testing WSU Tech#: 12-1110 Technology Summary: Preeclampsia is a pregnancy complication characterized by high blood pressure and...

Published: 3/3/2020 | Inventor(s): Nandor Than, Adi Tarca, Gabor Juhasz, Adrienna Kekesi, Hamutal Meiri, Zoltan Papp, Roberto Romero

Keywords(s):

Category(s): Medical, Biotechnology, Diagnostic, Diagnostics, Genomics/Genetics, Prenatal, Proteomics

Method for identifying Family-Member Specific Targets of Mono-PARPs

Summary Technology developed at OHSU provides a novel method to identify proteins regulated by PARP mono-ADP-ribosylation (MARylation), a post-translational modification carried out by the majority of enzymes within this family. This tool has the ability to link such PARPs to specific targets and broader biological pathways, thereby increasing our understanding...

Published: 9/29/2022 | Inventor(s): Michael Cohen, Ian Carter-O'Connell, Rory Morgan, Haihong Jin

Keywords(s): Diagnostics - Platforms, Research Tools

Category(s): Diagnostics, Proteomics, Research Tools

Annexin A2 as a novel diagnostic marker for serous ovarian cancer

Technology Background: We have recently shown that annexin A2 is highly expressed in 90% of serous ovarian cancers, which is the most common subtype and is actively involved in the process of ovarian cancer metastasis. Moreover, we have also shown that local upregulation of annexin A2 within the tumour is reflected in a systemic ~2.0-fold increase...

Published: 9/7/2017 | Inventor(s): Carmela Ricciardelli, Martin Oehler

Keywords(s): Biopharmaceuticals, Cancer, Diagnostics, Oncology, Reproductive

Category(s): Biomedical, Biotechnology, Diagnostic, Proteomics

Gastric Cancer Detection Test

Gastric cancer (GC) is the fourth most common cancer in the world and the second leading cause of cancer-related death. In Australia, the age standardised incident rate (ASR) is 9-10 per 100,000 people and over 11,000 deaths were recorded between 1996 and 2006. The current diagnostic strategy for GC is inadequate.The ability to detect early stage GC...

Published: 7/3/2018 | Inventor(s):

Keywords(s): Cancer, Diagnostics, Gastroenterology, Oncology

Category(s): Biotechnology, Proteomics, Medical, Diagnostic, Biomedical