Search Results - he+ba

79 Results Sort By:
REV-ERBα Modulators for the Treatment of Autoimmune Disorders
Activates the REV-ERBα Nuclear Receptor to Suppress TH17 Cell Development and TH17-Mediated Autoimmune and Chronic Inflammation These small molecules activate the REV-ERBα nuclear receptor to repress TH17 cell activity and treat autoimmune and chronic inflammatory disorders. TH17 cells are a subset of CD4+ T cells that play key roles in...
Published: 3/13/2025   |   Inventor(s): Laura Solt, Theodore Kamenecka, Yuanjun He, Brett Bookser, Mike Lizarzaburu
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Smart Nanoparticle-Based Cellular Transfection Tool for Therapeutic Development
Utilizes Light-Responsive Nanoparticles to Load Exosomes with Cargo Molecules Precisely and Efficiently, Maximizing Their Ability as Therapeutics This smart nanoparticle-based cellular transfection tool utilizes light-responsive nanoparticles to load therapeutic cargo molecules on demand into extracellular vesicles (EVs), or so-called exosomes, for...
Published: 2/26/2025   |   Inventor(s): Mei He
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Super-sodiophilic seeds for dendrite‑free sodium metal batteries
Background As the demand for renewable energy sources and electric vehicles grows, there is a pressing need for efficient, sustainable, and cost-effective battery tech­nologies. Sodium-metal batteries (SMBs) show great promise for energy storage applications due to the natural abundance and low cost of sodium compared to lithium. However, SMBs...
Published: 2/11/2025   |   Inventor(s): Arumugam Manthiram, Jiarui He, Amruth Bhargav
Keywords(s):  
Category(s): Physical sciences > Energy > Battery or electrochemical
Enhanced fluorescence via DNA aptamer optimization
This invention improves the fluorescence of DNA-based aptamers by sub­stituting the original fluorophore with TO1-biotin and identifying a critical mutation that further enhances fluorescence. Background Fluorogenic DNA aptamers (FAPs) are a crucial tool in molecular biology, particularly for applications like live-cell imaging and highly specific...
Published: 12/6/2024   |   Inventor(s): Hsin-Chih (Tim) Yeh, Yuan-I Chen, Yu-An Kuo, Yujie He, Trung Nguyen, Soonwoo Hong, Anh-Thu Nguyen, Sohyun Kim, Saeed Seifi
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform
Fluorescence lifetime imaging for retinal function assessment
This invention uses a laser-based imaging system to study the eye’s retina. By measuring light responses, it provides insights into retinal health and potential diseases like age-related macular degeneration. Background Two-photon excited fluorescence (TPEF) is a powerful technique used to study the eye. TPEF allows researchers to excite intrinsic...
Published: 10/24/2024   |   Inventor(s): Hsin-Chih (Tim) Yeh, Trung Nguyen, Yuan-I Chen, H. Grady Rylander, Yu-An Kuo, Soonwoo Hong, Anh-Thu Nguyen, Yujie He
Keywords(s):  
Category(s): Life sciences > Imaging, Life sciences > Imaging > Microscopy
Enhanced VR Battery Life through Perception-Guided Color Encoding
Innovative VR display power reduction using color perception technology, which enhances battery life without sacrificing visual quality Institute Reference: 1-24019 Background The rapid advancement of Virtual Reality (VR) and Augmented Reality (AR) technologies has resulted in a growing demand for higher resolution, faster refresh rates, and improved...
Published: 10/22/2024   |   Inventor(s): Yuhao Zhu, Abhishek Tyagi, Jiayi He, Budmonde Duinkharjav, Kenneth Chen, Qi Sun, Nisarg Ujjainkar
Keywords(s):  
Category(s): Optics, Computer Software, Devices
Affinity measurement and sequencing of T cell receptor
The technology enables the measurement of T cell receptor (TCR) affinity and sequencing of antigen-specific T cells using a micropipette adhesion assay and single-cell paired TCRα/TCRβ sequencing. The method isolates antigen-specific T cells, measures TCR affinity, and determines TCR sequences for applications in immunotherapy and monitoring...
Published: 9/13/2024   |   Inventor(s): Ning (Jenny) Jiang, Shuqi Zhang, Keyue Ma, Chenfeng He
Keywords(s):  
Category(s): Life sciences > Immunology, Life sciences > Research tools > Tool/assay/screening platform
Liquid Metal Printing Technique via Optical Maskless Lithography (Case No. 2024-031)
Summary: Researchers in the UCLA Department of Materials Science and Engineering have developed a facile, rapid method to print soft, wearable electronics. Background: Soft electrical circuits have garnered significant interest in a broad range of emerging technologies, including wearable electronics, brain-machine interfaces, and soft robotics....
Published: 3/6/2025   |   Inventor(s): Ximin He, Dong Wu
Keywords(s): Coating, Coatings, Adhesives, & Inks, Electronics & Semiconductors, Fabrication Technologies, gallium-based liquid metals, General Device Coatings, Liquid metal particles, liquid metals, Metals, Microelectronics Semiconductor Device Fabrication, Polymer, Polymers, scalable fabrication, Semiconductor Device Fabrication, soft electrical circuits, soft electronics, wearable electronics, wearable sensors
Category(s): Chemical, Chemical > Polymers, Chemical > Coatings, Adhesives & Inks, Electrical, Electrical > Electronics & Semiconductors, Electrical > Sensors, Electrical > Instrumentation, Electrical > Flexible Electronics, Materials, Materials > Fabrication Technologies, Materials > Composite Materials, Materials > Metals
Controlled Tunnel Gap Device for Sequencing Polymers
To reduce costs and increase the availability of personalized genomics new approaches to DNA sequencing are required. Nanopore sequencing is one proposed technique. In nanopore sequencing, DNA molecules are forced through a tiny aperture by electrophoresis. As the individual bases transit the nanopore, their identity can be determined, in theory, by...
Published: 2/13/2025   |   Inventor(s): Stuart Lindsay, Shuai Chang, Jin He, Peiming Zhang, Shuo Huang
Keywords(s): Bio-Technology
Category(s): Life Science (All LS Techs)
DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules
The US Government’s pursuit of the “Thousand Dollar Genome” and the “X Prize” goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will...
Published: 2/13/2025   |   Inventor(s): Stuart Lindsay, Colin Nuckolls, Jinyao Tang, Jin He, Peiming Zhang, Kevin Reinhart
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools
1 2 3 4 5 6 7 8