Search Results - jiarui+he

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nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Hongmin Li, Rui Xiong, Subodh Samrat, Malla Reddy Gannarapu, Ran Zhang, Ke Chen, Mengjiao Ma, Omar Alejandro Lozano Ramos, Divakar Indukuri, Renu Bhardwaj
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 5/1/2026   |   Updated: 3/23/2026   |   Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
Development of SelU Inhibitors as New Antibiotics
Scientists discovered that special chemical modifications on bacterial tRNA help control protein production and stress responses. They have also developed novel compounds that take advantage of this mechanism to produce antibiotic effects. Background: The field of epitranscriptomics focuses on the chemical modifications of RNA molecules, which are...
Published: 3/5/2026   |   Updated: 3/5/2026   |   Inventor(s): Jia Sheng, Thomas Begley
Keywords(s): antibiotics, inhibitors, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Drug Design and Synthesis
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026   |   Updated: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 3/20/2026   |   Updated: 10/24/2025   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Direct Carrier Fractional Frequency Synthesizer Using a DiCAD-Based Digital-To-Phase Modulator (Case No. 2025-9AA)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a low-noise, DiCAD-based fractional frequency synthesis system that enables fine frequency resolution and enhanced signal stability for millimeter-wave applications. Background: Millimeter-wave (mmW) communication and radar systems demand carrier frequency...
Published: 10/16/2025   |   Updated: 10/16/2025   |   Inventor(s): Mau-Chung Chang, Christopher Chen, Adrian Tang, Jia Zhou
Keywords(s): 5G, Automotive, Bandwidth (Signal Processing), Communications Satellite, efficiency bandwidth products, electrically-mediated sensing, Extremely High Frequency, Frequency conversion, frequency modulation, high frequency electronics, high-frequency signals, high-speed communications, Imaging, millimeter-wave, Millimeterwave network, Quantum Computer, Radar, satellite imaging, Signal-To-Noise Ratio, Telecommunication
Category(s): Electrical, Electrical > Signal Processing, Software & Algorithms > Communication & Networking, Electrical > Electronics & Semiconductors > Circuits, Software & Algorithms
A class of anion redox active materials for rechargeable batteries
Background The rapid evolution of battery technologies has ignited a fervent quest for safer, more efficient, and sustainable solutions. As lithium-ion batteries (LIBs) continue to dominate the market, concerns about the availability and cost of lithium resources have spurred interest in alternative battery chemistries. Among the emerging contenders,...
Published: 2/17/2026   |   Updated: 10/6/2025   |   Inventor(s): Arumugam Manthiram, Jiarui He, Amruth Bhargav
Keywords(s):  
Category(s): Physical sciences > Energy > Battery or electrochemical
Non-flammable electrolyte mixtures for high-stability alkali-metal batteries
Background As the demand for sustainable energy storage solutions grows during the advancement of portable electronics and electric vehicles, there is a pressing need for enhanced energy storage systems. Alkali-metal batteries are a promising solution for energy storage due to their high energy-density capabilities. However, their widescale adoption...
Published: 2/17/2026   |   Updated: 10/3/2025   |   Inventor(s): Arumugam Manthiram, Jiarui He, Amruth Bhargav
Keywords(s):  
Category(s): Physical sciences > Energy > Battery or electrochemical
Antimicrobial Antibody Signatures of IBD
The incidence of inflammatory bowel disease (IBD), which includes Chron’s disease (CD) and ulcerative colitis (UC), is increasing globally, as is the healthcare burden, with studies showing it as one of the top 5 most expensive GI conditions. Early and accurate diagnosis is strongly associated with better patient outcomes. However, the common...
Published: 2/26/2026   |   Updated: 8/27/2025   |   Inventor(s): Mahasish Shome, Lusheng Song, Yunro Chung, Jonathan Leighton, Joshua LaBaer, Ji Qiu
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Biodegradable Polymers for Gene Delivery
​ Invention Summary: In gene therapy, a key challenge is delivering therapeutic genes to target cells, which requires gene delivery vectors. While viral vectors are effective, they pose risks such as immune responses and toxicity. Non-viral vectors, particularly cationic polymers, are preferred for their safety, cost-effectiveness, and high...
Published: 2/20/2026   |   Updated: 6/5/2025   |   Inventor(s): Adam Gormley, David Radford, Prajakatta Mulay, Jia Niu, Brayan Rondon
Keywords(s):  
Category(s): Technology Classifications > Agriculture, Technology Classifications, Technology Classifications > Physical Sciences & Engineering
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