Search Results - jiayi+he

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DNAzyme-based biosensor technology for selective and real-time detection of potassium ions in biological systems
Background The ability to monitor potassium ion (K+) dynamics is of critical importance, particularly in the context of cancer research and neurobiology. Potassium ions play a fundamental role in maintaining cellular homeostasis, regulating membrane potential, and influencing processes such as cell proliferation, apoptosis, and immune responses. Disruptions...
Published: 1/27/2026   |   Inventor(s): Yi Lu, Zhenglin Yang, Xiangli Shao, Yuting Wu
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Research tools > Tool/assay/screening platform
Development of SelU Inhibitors as New Antibiotics
Scientists discovered that special chemical modifications on bacterial tRNA help control protein production and stress responses. They have also developed novel compounds that take advantage of this mechanism to produce antibiotic effects. Background: The field of epitranscriptomics focuses on the chemical modifications of RNA molecules, which are...
Published: 1/30/2026   |   Inventor(s): Jia Sheng, Thomas Begley
Keywords(s): antibiotics, inhibitors, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Drug Design and Synthesis
DNAzyme-seq: a single-cell metal ion and transcriptome profiling platform
Background Metal ions such as zinc, copper, and calcium play indispensable roles in nearly every facet of cellular physiology, from enzymatic catalysis to signal trans­duction. However, conventional single-cell transcriptomics has largely over­looked the contribution of metal cofactors to gene expression, metabolism, and disease progression....
Published: 1/13/2026   |   Inventor(s): Yi Lu, Mandira Banik, Valeria Garcia, Ishika Rashed
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology > Genomics/genetics
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 1/30/2026   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Design of Task-Specific Optical Systems Using Broadband Diffractive Neural Networks (Case No. 2020-174)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a diffractive neural network that can process an all-optical, 3D printed neural network for deep learning applications. Background: Deep learning, a method of machine learning that mimics the human brain’s connectivity through a series of “neural...
Published: 10/17/2025   |   Inventor(s): Aydogan Ozcan, Yi Luo, Deniz Mengu, Yair Rivenson
Keywords(s):  
Category(s): Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing
Direct Carrier Fractional Frequency Synthesizer Using a DiCAD-Based Digital-To-Phase Modulator (Case No. 2025-9AA)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a low-noise, DiCAD-based fractional frequency synthesis system that enables fine frequency resolution and enhanced signal stability for millimeter-wave applications. Background: Millimeter-wave (mmW) communication and radar systems demand carrier frequency...
Published: 10/16/2025   |   Inventor(s): Mau-Chung Chang, Christopher Chen, Adrian Tang, Jia Zhou
Keywords(s): 5G, Automotive, Bandwidth (Signal Processing), Communications Satellite, efficiency bandwidth products, electrically-mediated sensing, Extremely High Frequency, Frequency conversion, frequency modulation, high frequency electronics, high-frequency signals, high-speed communications, Imaging, millimeter-wave, Millimeterwave network, Quantum Computer, Radar, satellite imaging, Signal-To-Noise Ratio, Telecommunication
Category(s): Electrical, Electrical > Signal Processing, Software & Algorithms > Communication & Networking, Electrical > Electronics & Semiconductors > Circuits, Software & Algorithms
Cascadable All-Optical Nand Gates Using Diffractive Networks (Case No. 2022-107)
Summary UCLA researchers have developed cascadable, all-optical NAND gates built from passive diffractive neural networks, enabling logic operations (e.g. NAND, AND, OR, half-adder) via light propagation and diffraction rather than electronics, potentially lowering latency and power consumption. Background Traditional optical logic gates often rely...
Published: 9/11/2025   |   Inventor(s): Aydogan Ozcan, Yi Luo
Keywords(s):  
Category(s): Electrical, Electrical > Signal Processing, Electrical > Electronics & Semiconductors
Antimicrobial Antibody Signatures of IBD
The incidence of inflammatory bowel disease (IBD), which includes Chron’s disease (CD) and ulcerative colitis (UC), is increasing globally, as is the healthcare burden, with studies showing it as one of the top 5 most expensive GI conditions. Early and accurate diagnosis is strongly associated with better patient outcomes. However, the common...
Published: 8/27/2025   |   Inventor(s): Mahasish Shome, Lusheng Song, Yunro Chung, Jonathan Leighton, Joshua LaBaer, Ji Qiu
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Biocompatible photoenzymatic system for selective C–H fluorination
Background C–H fluorination plays a central role in pharmaceutical and agrochemical synthesis, as the introduction of fluorine often enhances a molecule's metabolic stability, potency, and bioavailability. Over 20% of approved drugs contain fluorinated functional groups, underscoring the demand for efficient and selective fluorination methods....
Published: 1/13/2026   |   Inventor(s): Yi Lu, Yu Zhou
Keywords(s):  
Category(s): Life sciences > Metabolic engineering
Multi-List Strategy for Spectrum Interference Management
THE CHALLENGE Spectrum managers operating in shared-spectrum environments (e.g., the CBRS band) face a critical challenge: protecting high-priority incumbents such as Navy radar while maintaining reliable service for commercial users. Static move lists—the prevailing industry approach—repeatedly shut down the same base stations during...
Published: 11/17/2025   |   Inventor(s): Naru Jai, Yubo Wu, Yi Shi, Yiwei Thomas Hou
Keywords(s):  
Category(s): Technology Classifications > Communication
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