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Search Results - keyue+ma
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Affinity measurement and sequencing of T cell receptor
The technology enables the measurement of T cell receptor (TCR) affinity and sequencing of antigen-specific T cells using a micropipette adhesion assay and single-cell paired TCRα/TCRβ sequencing. The method isolates antigen-specific T cells, measures TCR affinity, and determines TCR sequences for applications in immunotherapy and monitoring...
Published: 9/13/2024
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Inventor(s):
Ning (Jenny) Jiang
,
Shuqi Zhang
,
Keyue Ma
,
Chenfeng He
Keywords(s):
Category(s):
Life sciences > Immunology
,
Life sciences > Research tools > Tool/assay/screening platform
High-throughput sequencing technology for T-cell receptor specificity
TetTCR-seq is a method for high-throughput pairing of T cell receptor (TCR) sequences with their specific antigens using DNA-barcoded pMHC tetramers, enabling rapid, cost-effective immune profiling, disease diagnosis, and therapeutic development. Background The identification of antigen-specific T-cell receptors (TCRs) is crucial for understanding...
Published: 8/7/2024
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Inventor(s):
Ning (Jenny) Jiang
,
Shuqi Zhang
,
Chenfeng He
,
Keyue Ma
Keywords(s):
Category(s):
Life sciences > Research tools > Tool/assay/screening platform
,
Life sciences > Immunology
Lens with Electronically Controlled Optical Properties
Executive SummaryThis MSU-developed device allows for electrical control of the optical properties in a liquid lens and other optic devices. Capable of altering light’s focal point, this technology lends itself into many applications such as displays, microscopes, telescopes, interferometers, and many more. Description of TechnologyBy controlling...
Published: 8/20/2022
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Inventor(s):
Gary Blanchard
,
Greg Swain
,
Romana Jarosova
,
Ke Ma
Keywords(s):
Category(s):
Advanced Materials
,
Chemicals
,
Devices
,
Photonics