Search Results - ximin+he

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Liquid Metal Printing Technique via Optical Maskless Lithography (Case No. 2024-031)
Summary: Researchers in the UCLA Department of Materials Science and Engineering have developed a facile, rapid method to print soft, wearable electronics. Background: Soft electrical circuits have garnered significant interest in a broad range of emerging technologies, including wearable electronics, brain-machine interfaces, and soft robotics....
Published: 9/24/2024   |   Inventor(s): Ximin He, Dong Wu
Keywords(s): Coating, Coatings, Adhesives, & Inks, Electronics & Semiconductors, Fabrication Technologies, gallium-based liquid metals, General Device Coatings, Liquid metal particles, liquid metals, Metals, Microelectronics Semiconductor Device Fabrication, Polymer, Polymers, scalable fabrication, Semiconductor Device Fabrication, soft electrical circuits, soft electronics, wearable electronics, wearable sensors
Category(s): Chemical, Chemical > Polymers, Chemical > Coatings, Adhesives & Inks, Electrical, Electrical > Electronics & Semiconductors, Electrical > Sensors, Electrical > Instrumentation, Electrical > Flexible Electronics, Materials, Materials > Fabrication Technologies, Materials > Composite Materials, Materials > Metals
Accelerating Multiview Registration and Iterative Deconvolution to Improve Spatial Resolution and Contrast in Fluorescence Microscopy
This technology includes algorithms and software that improve the speed of iterative deconvolution, a common method for improving spatial resolution and contrast in fluorescence microscopy images. These algorithms also improve the registration of multiview datasets, and apply deep learning to accelerate spatially varying deconvolution.
Published: 8/12/2024   |   Inventor(s): Hari Shroff, Yue Li, Yicong Wu, Patrick La Riviere, Min Guo, Huafeng Liu
Keywords(s):  
Category(s): Application > Research Materials, Application > Software / Apps, ResearchProducts > Research Equipment
Improvement of Axial Resolution via Photoswitching and Standing Wave Illumination
This technology includes an illuminator and reflector that enables flexible standing wave illumination on an inverted microscope stand, and procedures for using such illumination to improve axial resolution in confocal or instant SIM imaging systems. The axial resolution in conventional fluorescence microscopy is typically limited by diffraction to...
Published: 8/12/2024   |   Inventor(s): Hari Shroff, John Giannini, Yicong Wu, Patrick La Riviere, Min Guo, Jiji Chen, Harshad Vishwasrao
Keywords(s):  
Category(s): Application > Research Materials, Application > Software / Apps, ResearchProducts > Computational models/software, ResearchProducts > Research Equipment
Computational Alleviation of Depth-dependent Degradation in Fluorescence Images
This technology includes an approach that dramatically lessens the effects of depth-dependent degradation in fluorescence microscopy images. First, we develop realistic ‘forward models’ of the depth dependent degradation and apply these forward models to shallow imaging planes that are expected to be relatively free of such degradation....
Published: 8/12/2024   |   Inventor(s): Hari Shroff, Yicong Wu, Min Guo, Patrick La Riviere
Keywords(s):  
Category(s): Application > Software / Apps, Collaboration Sought > Licensing, ResearchProducts > Computational models/software
Instant Total Internal Reflection Fluorescence/Structured Illumination Microscopy (instant TIRF/SIM)
This technology includes a method which enables high-speed, super-resolution microscopy at a very high signal-to-noise ratio (SNR), for biological applications within ~200 nm (the evanescent wave decay length) of a coverslip surface. Instant TIRF/SIM may be implemented simply by modifying and adding to the excitation optics that are already present...
Published: 8/12/2024   |   Inventor(s): Hari Shroff, Justin Taraska, Abhishek Kumar, Min Guo
Keywords(s):  
Category(s): Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment
Ion-Solvent-Polymer Interactions for Preparing Polymer Networks and Composites of Tunable Structures and Properties (UCLA Case No. 2023-147)
Summary: Researchers in UCLA's Department of Materials Science and Engineering have developed a solution-based synthesis platform capable of generating micro and nanostructured gels, polymers, and composites with simultaneously improved safety, mechanical and ionic conductivity/transport properties. Background: Pore structure engineering holds...
Published: 7/30/2024   |   Inventor(s): Ximin He
Keywords(s):  
Category(s): Chemical, Chemical > Polymers, Chemical > Synthesis, Energy & Environment, Energy & Environment > Energy Storage, Materials, Materials > Fabrication Technologies, Materials > Functional Materials, Materials > Composite Materials
Levonorgestrel Butanoate Formulation and Methods Relating Thereto
Abstract: This invention is a potential subcutaneous or intramuscular progestin-only, injectable contraceptive for women. Forty-five percent (45%) of pregnancies in the United States are unintended. In this group, one-third of reproductive age women are obese – increasing the risk of diabetes, hypertension and venous thromboembolism (VTE). All these...
Published: 4/8/2024   |   Inventor(s): Min Lee, Diana Blithe, Jia-Hwa Fang, Eduardo Ruiz, Ken Chen
Keywords(s): Blithe, CONTRACEPTIVE, INJECTABLE, LB, Lee, Levonorgestrel, Levonorgestrel Butanoate, LNG, National Institute of Child Health and Human Development, NICHD, Steroidal Progestin
Category(s): TherapeuticArea > Endocrinology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Reproductive Health
Novel Human Insulin Cα-Peptide as an Antagonist for Islet and Brain Amyloidosis
Abstract: Over 32 million Americans are living with Diabetes and newly diagnosed cases of type 1 and type 2 diabetes is increasing. A defining feature of type 2 diabetes mellitus (T2DM) is the accumulation of islet amyloid polypeptide (IAPP) fibrils in pancreatic islets. Such accumulations form amyloid plaques, referred to as islet amyloidosis. Mounting...
Published: 4/8/2024   |   Inventor(s): Qing Rong Liu, Min Zhu, Pingbo Zhang, Josephine Egan, Luigi Ferrucci
Keywords(s): Alzheimer’s Disease, Amyloidosis, C-peptide, DIABETES, Egan, insulin, Islet Amyloid Polypeptide, Liu, National Institute on Aging, NIA
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Endocrinology
Monomeric and Oligomeric Compounds as Contraceptives and Endocrine Therapeutics
Abstract: The options for male contraceptives are limited. Research is ongoing to develop a male contraceptive based on hormonal activity. Testosterone is one of the hormones necessary in producing sperm. Testosterone is absolutely required as a hormone for male fertility. Derivatives of testosterone for male contraceptives currently in clinical trials...
Published: 4/8/2024   |   Inventor(s): Min Lee, Diana Blithe, Pranab Gupta, Bashir Kaskar, Ming-Teh Lin
Keywords(s): Blithe, CONTRACEPTIVE, Estrogenic Activity, Eunice Kennedy Shriver National Institute of Child Health an, Lee, Male Contraceptive, MONOMERIC, NCE, New Chemical Entity, NICHD, OLIGOMERIC
Category(s): Application > Therapeutics, TherapeuticArea > Reproductive Health, TherapeuticArea > Endocrinology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Novel Human Islet Amyloid Polypeptides as Alzheimer’s Disease Biomarkers and Inhibitors of Amyloid Formation
Abstract: Over 34 million Americans are living with diabetes. An estimated 6.5 million Americans are living with Alzheimer’s disease (AD) and type 2 diabetes mellites (T2DM). Amyloidosis due to aggregation of amyloid-β is key pathogenic event in AD, whereas aggregation of mature islet amyloid polypeptide (IAPP37) in human islet leads to β-cell dysfunction....
Published: 5/23/2024   |   Inventor(s): Qing Rong Liu, Min Zhu, Josephine Egan
Keywords(s): Ad, Age-Associated Disease, Alzheimer’s Disease, Amyloidosis, Amyloids, Biomarkers, DIABETES, IAPP, Islet Amyloid Polypeptide Isoforms, Liu, National Institute on Aging, NIA, PEPTIDYL
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
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