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REV-ERBα Modulators for the Treatment of Autoimmune Disorders
Activates the REV-ERBα Nuclear Receptor to Suppress TH17 Cell Development and TH17-Mediated Autoimmune and Chronic Inflammation These small molecules activate the REV-ERBα nuclear receptor to repress TH17 cell activity and treat autoimmune and chronic inflammatory disorders. TH17 cells are a subset of CD4+ T cells that play key roles in...
Published: 3/13/2025   |   Inventor(s): Laura Solt, Theodore Kamenecka, Yuanjun He, Brett Bookser, Mike Lizarzaburu
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics