Search Results - yuanjun+he

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Task-Oriented Edge Metaverse for Smart Cities and Critical Systems
This invention introduces a task-oriented “Microverse” architecture that creates temporary, edge-based digital twins for 5G/IoT network slices. By combining real-time data fusion, per-task blockchain security, and immersive VR/AR interfaces, it delivers sub-second situational awareness and secure collaboration for smart cities, infrastructure,...
Published: 10/17/2025   |   Inventor(s): Yu Chen, Qian Qu
Keywords(s): Technologies
Category(s): Campus > Binghamton University
Pressure-assisted 3D printing for tunable micro/nanoparticle drug delivery
Background In the realm of drug delivery and biomedical therapies, advanced formulations are essential for improving treatment efficacy, minimizing systemic toxicity, and achieving precise therapeutic targeting. Technologies capable of encapsu­lating and preserving the bioactivity of small molecules, proteins, and live cells are particularly critical...
Published: 10/3/2025   |   Inventor(s): Mohammed Maniruzzaman, Jiawei Wang, Niloofar Aghda, Yu Zhang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
IL-2 Independent Ultrahigh Human T Cell Activations Through Biomimetics of Immune Synapses by Graphene Oxides (UCLA Case No. 2021-068)
UCLA researchers in the Department of Materials Science and Engineering have constructed a novel graphene oxide-based platform for robust T cell activation through artificial immune synapse formation. BACKGROUND: T cells are a critical arm of the immune system with tremendous therapeutic value for immune disorders and cancer. However, modulation of...
Published: 10/2/2025   |   Inventor(s): Yu Huang, Lili Yang
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Self-Assembling HER2 Nanobody Liposomes: Smarter Cancer Drug Delivery
This invention introduces a one-step self-assembly method that integrates HER2-targeted chimeric nanobodies directly into liposomal membranes, enabling scalable production of immunoliposomes with high drug encapsulation, improved tumor targeting, and reduced manufacturing complexity. Background: HER2-targeted therapies have shown promise for treating...
Published: 9/26/2025   |   Inventor(s): Yuan Wan, Mofizur Rahman
Keywords(s): Technologies
Category(s): Campus > Binghamton University
DARTS: A Drone-Based AI-Powered Real-Time Traffic Incident Detection System
Advantages All-weather reliability with thermal-AI fusion ensuring uninterrupted traffic monitoring. Automated incident verification delivers alerts faster, reducing emergency response times. Privacy-preserving trajectory analysis safeguards driver identity while ensuring roadway safety. Scalable drone deployment eliminates costly infrastructure...
Published: 9/16/2025   |   Inventor(s): Bai Li, Yu Zhang
Keywords(s): Artificial Intelligence, Automotive /Traffic Tech, Optics and Imaging
Category(s): Technology Classifications > Engineering > Drones, Technology Classifications > Computer Science > C/S Transportation, Technology Classifications > Computer Science > Algorithms
Self-Powered Electrical Stimulation Magnetoelastic Bandage for Accelerated Wound Healing (Case No. 2025-99N)
Reference: UCLA Case No. 2025-99N Please reach out to our office for more information.
Published: 10/10/2025   |   Inventor(s): Jun Chen, Kanishk Rai, Song Li, Il Woo Ock, Haochen Nan
Keywords(s):  
Category(s): Therapeutics, Therapeutics > Aesthetic Medicine, Materials, Materials > Functional Materials, Materials > Membranes, Electrical, Electrical > Flexible Electronics
A Smart Pen for Parkinson’s Disease Diagnostics (Case No. 2025-283)
Summary UCLA researchers have developed a smart pen for Parkinson’s Disease (PD) diagnostics that converts handwriting motions—both on paper and in air—into high-fidelity voltage signals for accurate, accessible, and low-cost disease screening. This pen leverages magnetoelastic sensing and ferrofluid ink to enable self-powered, quantitative...
Published: 9/12/2025   |   Inventor(s): Jun Chen, Guorui Chen
Keywords(s):  
Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Medical Devices > Hospital Systems, Diagnostic Markers, Diagnostic Markers > Aging
TDP-43 In Vivo Mouse Model
This is an in vivo mouse model of TDP-43 proteinopathy that captures key features of human neurodegenerative disease, particularly Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD). The model targets a disease-relevant disruption in TDP-43’s interaction with cytoplasmic translational machinery, causing a cascade...
Published: 9/2/2025   |   Inventor(s): Xinglong Wang, Ju Gao
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Research Tools > Animal Models
SPLICER: Small Molecule-Inducible Gene Expression Switches
Enables Ligand-Inducible Regulation of Gene Expression or Knockdown This small molecule-inducible gene expression based on riboswitches (SPLICER) enables precise, drug-responsive control of gene expression for safer and more flexible gene and cell therapies. In mammalian cells, alternative splicing greatly expands the diversity of RNA sequences. These...
Published: 9/2/2025   |   Inventor(s): Eric Wang, Yu Zhou
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Fluorescence Polarization Probe for identifying inhibitors of Enterovirus D68 2C
​ Design of the 2C fluorescence polarization probe Jun14157 and assay. See link to paper below. Invention Summary: The genus Enterovirus of Picornaviridae contains many significant pathogens related to human and mammalian diseases. Enterovirus D68 (EV-D68) infection is linked to the neurological disorder acute flaccid myelitis (AFM), where...
Published: 8/20/2025   |   Inventor(s): Jun Wang, Kan Li
Keywords(s):  
Category(s): Technology Classifications > Infectious Disease, Technology Classifications > Research Tools, Technology Classifications > Therapeutics
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