Search Results - shuqi+zhang

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Quantum device using insulating topological material
Quantum device using insulating topological material Princeton Docket # 24-4093-1 Current quantum electronic devices often rely on conducting materials, which can limit their efficiency and scalability due to energy loss and interference from bulk conducting states. Princeton researchers have made a significant breakthrough in this field by developing...
Published: 10/21/2024   |   Inventor(s): M. Zahid Hasan, Md. Shafayat Hossain, Qi Zhang, Zhiwei Wang, Bing Lv, Yugui Yao
Keywords(s):  
Category(s): Quantum Computing and Electrical Engineering
Affinity measurement and sequencing of T cell receptor
The technology enables the measurement of T cell receptor (TCR) affinity and sequencing of antigen-specific T cells using a micropipette adhesion assay and single-cell paired TCRα/TCRβ sequencing. The method isolates antigen-specific T cells, measures TCR affinity, and determines TCR sequences for applications in immunotherapy and monitoring...
Published: 9/13/2024   |   Inventor(s): Ning (Jenny) Jiang, Shuqi Zhang, Keyue Ma, Chenfeng He
Keywords(s):  
Category(s): Life sciences > Immunology, Life sciences > Research tools > Tool/assay/screening platform
High-throughput sequencing technology for T-cell receptor specificity
TetTCR-seq is a method for high-throughput pairing of T cell receptor (TCR) sequences with their specific antigens using DNA-barcoded pMHC tetramers, enabling rapid, cost-effective immune profiling, disease diagnosis, and therapeutic development. Background The identification of antigen-specific T-cell receptors (TCRs) is crucial for understanding...
Published: 8/7/2024   |   Inventor(s): Ning (Jenny) Jiang, Shuqi Zhang, Chenfeng He, Keyue Ma
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology
A Modular Strategy for Distributed, Embodied Control of Electronics-Free Soft Robots
A kirigami-inspired robot made without hard electronic controls, with soft modular sensors for navigating diverse environments. Problem: Soft robots are promising new machines that can adapt and operate in diverse confined and dynamic environments. Such machines are promising for industrial manufacturing, exploratory, and medical applications. For...
Published: 2/7/2024   |   Inventor(s): Jordan Raney, Qiguang He, Rui Yin, Yucong Hua, Jiao Weijian, Chengyang Mo, Hang Shu
Keywords(s): Soft Materials
Category(s): Technology Classifications > Robotics
COMBINATION THERAPIES FOR COVID-19 (SARS-COV-2)
The coronavirus disease 2019 (COVID-19) is caused by a novel RNA enveloped coronavirus, SARS-CoV-2 when the virus enters human airway cells via an ACE2-mediated entry process. This entry pathway is facilitated by the cell surface heparan sulfate proteoglycan (HSPG), which enhances viral attachment to the cell surface. Researchers at NIDDK and NCATS...
Published: 10/28/2024   |   Inventor(s): Qi Zhang, Wei Zheng, Catherine Chen, Yihong Ye
Keywords(s): COVID-19, DB4BXX, ENTRY, HEPARAN, option, Sulfate-dependent, Targeting, therapeutic, viral
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Therapeutics
A method to label heparan sulfate proteoglycan in the plasma membrane of mammalian cells
Heparan sulfate proteoglycan (HSPG) is a group of lipid-anchored proteoglycans, engaged in a variety of key biological functions on cell surface. HSPG-mediated endocytosis of neurotoxic protein aggregates has been linked to aging related neurodegenerative diseases. Labeling HSPG is a promising technique to trace cell profile in cell research, monitor...
Published: 10/28/2024   |   Inventor(s): Qi Zhang, Yihong Ye
Keywords(s): Cells, HEPARAN, Label, MAMMALIAN, MEMBRANE, Method, PLASMA, PROTEOGLYCAN, R1XXXX, SULFATE, XCXXXX
Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023   |   Inventor(s): Leilei Peng, Yu Li, Han Zhang
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Systems and Methods of Using Phase Change Material in Power Plants
PAGE TITLEOverviewPAGE SUMMARY Cooling systems and methods for cooling in a power plant using a phase change material. In one embodiment, a phase change material container includes at least one phase change material which may be in the form of a slurry; and at least one conduit for transporting the fluid through the phase change material when located...
Published: 7/24/2024   |   Inventor(s): Matthew Mccarthy, Ying Sun, Young Cho, Baolan (jessica) Shi, Han Hu, Philipp Boettcher, Qinghua (tim) Xie
Keywords(s):  
Category(s): Energy, Mechanical & Civil Engineering, Energy > Energy: Heat Exchangers, Energy > Energy: Power Plants, Mechanical & Civil Engineering > ME-CE: HVAC
A Mutually Inhibitory Network with Positive Autoregulation and Communications (MINPAC)
Biological pattern formation requires complex gene regulation networks and accurate cell-cell coordination. The reaction-diffusion (RD) based clock and wavefront model has been proposed as a mechanism involved in biological pattern formation of repeated and segmented structures. While RD driven pattern formation has been demonstrated in many systems,...
Published: 2/23/2023   |   Inventor(s): Fuqing Wu, Samat Bayakhmetov, Changhan He, Qi Zhang, Xingwen Chen, Yang Kuang, Xiao Wang
Keywords(s):  
Category(s): Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Computing & Information Technology
Pathogen Molecular Detection Platform
Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...
Published: 2/23/2023   |   Inventor(s): Qi Zhang, Xiao Wang, Alexander Green, Duo Ma, Fuqing Wu, Kylie Standage-Beier, Xingwen Chen
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors
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