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­Low-cost fluorescent reporters for nuclease activity detection
Problem DNA cleavage or nuclease activity detection is important in many forms of nucleic acid amplification tests. The current detection technologies rely on the use of fluorescence resonance energy transfer (FRET) reporters that light up upon digestion, such as the Taqman® probe and the DNaseAlert®. Although these FRET reporters well serve...
Published: 6/6/2024   |   Inventor(s): Hsin-Chih (Tim) Yeh, Soonwoo Hong, Yuan-I Chen, Yu-An Kuo, Trung Nguyen, Hsin-Chin Li
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Agriculture > Animal/veterinary
Deep learning for rapid and robust fluorescence lifetime imaging
Deep-learning approach has the potential to unlock fluorescent lifetime imaging for clinical applications. Fluorescence lifetime imaging microscopy (FLIM) is a widely used tool for biomedical imaging that offers many unique advantages over typical intensity-based fluorescence microscopy. FLIM is advancing fundamental biological research by enabling...
Published: 11/1/2023   |   Inventor(s): Hsin-Chih (Tim) Yeh, Yuan-I Chen, Yin-Jui Chang, Shih-Chu Liao, Trung Nguyen, Soonwoo Hong, Yu-An Kuo, Hsin-Chin Li
Keywords(s): Artificial intelligence (AI), Cancer, Diagnostics, Imaging, Machine learning, Medical imaging, Microscopy
Category(s): Life sciences > Imaging > Microscopy, Life sciences > Imaging