Search Results - peiming+zhang

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VALUE PROPOSITION Rail transportation is periodically marred by accidents, highlighting ongoing safety challenges. There is a need for effective rail inspection methods. Current techniques are hindered by limitations such as low detection accuracy and sensitivity, particularly at high speeds. This technology introduces a novel method for high-speed,...

Published: 9/27/2024 | Inventor(s): Yiming Deng, Sunil Chakrapani, Ming Han, Zebadiah Miles

Keywords(s):

Category(s): Analytical Instruments, Test and Measurement, Transportation

Controlled Tunnel Gap Device for Sequencing Polymers

To reduce costs and increase the availability of personalized genomics new approaches to DNA sequencing are required. Nanopore sequencing is one proposed technique. In nanopore sequencing, DNA molecules are forced through a tiny aperture by electrophoresis. As the individual bases transit the nanopore, their identity can be determined, in theory, by...

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Shuai Chang, Jin He, Peiming Zhang, Shuo Huang

Keywords(s): Bio-Technology

Category(s): Life Science (All LS Techs)

Trans-Base Tunnel Reader for Sequencing

The US Government's pursuit of the "Thousand Dollar Genome" and the "X Prize" goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will open a new...

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Peiming Zhang, Kevin Reinhart

Keywords(s):

Category(s): Life Science (All LS Techs)

DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules

The US Government’s pursuit of the “Thousand Dollar Genome” and the “X Prize” goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will...

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Colin Nuckolls, Jinyao Tang, Jin He, Peiming Zhang, Kevin Reinhart

Keywords(s):

Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools

DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Jin He, Peiming Zhang, Kevin Reinhart

Keywords(s):

Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools

DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules

Published: 10/17/2024 | Inventor(s): Stuart Lindsay, Peiming Zhang

Keywords(s):

Category(s): Life Science (All LS Techs)

Whole Tissue Protein Mapping

A tool and method for precise, high-throughput spatial mapping of proteins across whole tissue samples. Background: Spatial proteomics enables delineation of spatial localization of proteins within cells and tissues. This ability to identify and study the relative location and quantification of one or more proteins, whether ones that are endogenously...

Published: 8/21/2024 | Inventor(s): Jun Qu, Ming Zhang, Min Ma

Keywords(s): Featured, Technologies

Category(s): Campus > University at Buffalo, Technology Classifications > Bioinformatics

Neutralization of Hepatitis C Virus (HCV)

Available for licensing and commercial development are compositions and methods for preventing and/or treating infection caused by hepatitis C virus (HCV). The invention is based on mapping studies conducted by the inventors of two epitopes within HCV E2: epitope I and epitope II. It has been discovered that epitope I is involved in virus neutralization...

Published: 10/28/2024 | Inventor(s): Pei Zhang

Keywords(s): antibodies, ANTIBODY, BINDING, C, Chromosome 7, monosomy, CONTROL, DB4BXX, DB4XXX, DBXXXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, Deletion 7, DXXXXX, E2, HCV, HCV Vaccine, Hepatitis A, Hepatitis D, Hepatitis E, Hepititis, Heptitis, Infection, Interference-mediated, INTERFERING, Methods, Modulate, Neutralization, Patent Category - Chemistry, Protein, SITE, virus

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Vaccines, Application > Therapeutics

Method for 3D Nonlinear Structured Illumination Super-resolution Imaging

Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Yu Li, Han Zhang

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Helical Sulfono-γ-AApeptide Antagonize β-Catenin Signaling

Competitive Advantages Potent, specific, and cell permeable to target intracellular PPIs High stability against enzymatic degradation More effective than other peptides at antagonizing Wnt/β-catenin signaling Summary Protein-protein interactions (PPIs) are vital to the survival of cancer cells and are therefore a good target for anti-cancer...

Published: 7/17/2023 | Inventor(s): Jianfeng Cai, Peng Sang, Yan Shi, Haitao Ji, Min Zhang

Keywords(s): Cancer, Cancer Treatment Leukemias, Cancer Treatment Lymphomas, Peptides, Therapeutics

Category(s): Technology Classifications > Cancer

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