Search Results - george+dodge

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A drug delivery system tuned to the endogenous mechanical environment
Technology Overview: Tissues within the body experience mechanical perturbations across multiple force magnitudes and length scales, from mechanotransduction at the cell level to the dynamics of load-bearing joints. These forces not only maintain tissue homeostasis, but can also initiate degenerative processes when applied at supra-physiologic levels....
Published: 6/21/2024   |   Inventor(s): Robert Mauck, George Dodge, Daeyeon Lee
Keywords(s): Drug Delivery
Category(s): Technology Classifications > Therapeutics
A Stretch-Activated Adhesive Microcapsule For The Controlled Release of Drugs In Wound-Healing Dressings
An adhesive drug-loaded microcapsule which releases therapeutic cargo upon mechanical stretching. Problem: Medicated dressings can improve healing of open wounds and improve pain management in patients. However, drug-coated bandages lack stimuli-response release mechanisms, so therapeutics are not released in a controlled and sustained manner. Poor...
Published: 6/20/2024   |   Inventor(s): Daeyeon Lee, Yun Kee Jo, Robert Mauck, George Dodge
Keywords(s): Drug Delivery, Soft Materials
Category(s): Technology Classifications > Materials