Search Results - robert+mauck

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A drug delivery system tuned to the endogenous mechanical environment
Technology Overview: Tissues within the body experience mechanical perturbations across multiple force magnitudes and length scales, from mechanotransduction at the cell level to the dynamics of load-bearing joints. These forces not only maintain tissue homeostasis, but can also initiate degenerative processes when applied at supra-physiologic levels....
Published: 6/21/2024   |   Inventor(s): Robert Mauck, George Dodge, Daeyeon Lee
Keywords(s): Drug Delivery
Category(s): Technology Classifications > Therapeutics
A Stretch-Activated Adhesive Microcapsule For The Controlled Release of Drugs In Wound-Healing Dressings
An adhesive drug-loaded microcapsule which releases therapeutic cargo upon mechanical stretching. Problem: Medicated dressings can improve healing of open wounds and improve pain management in patients. However, drug-coated bandages lack stimuli-response release mechanisms, so therapeutics are not released in a controlled and sustained manner. Poor...
Published: 6/20/2024   |   Inventor(s): Daeyeon Lee, Yun Kee Jo, Robert Mauck, George Dodge
Keywords(s): Drug Delivery, Soft Materials
Category(s): Technology Classifications > Materials
Modified Polymer System for Improved Cartilage Repair
Improved cartilage repair via injectable modified polymers that target damaged tissues and enhance cellular response Problem: Cartilage damage is one of the most common ailments in the aging population. Tissue damage, particularly cartilage damage, can occur due to traumatic injury, degeneration with time, and other soft tissue injuries. The inability...
Published: 1/11/2024   |   Inventor(s): Claudia Loebel, Anthony Martin, Robert Mauck, Jason Burdick, Jay Patel
Keywords(s): Regenerative Medicine
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Materials