Search Results - yu-shan+cheng

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Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation

Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...

Published: 10/2/2023 | Inventor(s): Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang

Keywords(s): Drug Discovery, Infectious Diseases Treatment

Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording. EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...

Published: 8/17/2023 | Inventor(s): Ada Poon, Cheng Chen, Joonseok Yang, Hui Wang

Keywords(s): EEG, Neurology, Wearable

Category(s): Technology Classifications > Engineering

Patient-derived induced pluripotent stem cell (iPSC) lines for the study of lysosomal storage diseases (LSDs)

This technology includes the generation and use of human induced pluripotent stem cell (iPSC) lines that can be used to study and screen potential therapeutics for lysosomal storage diseases (LSDs). LSDs are a group of 50 genetic disorders caused by mutations in the genes encoding lysosomal enzymes and proteins. Although various therapeutic approaches...

Published: 10/28/2024 | Inventor(s): Miao Xu, Yu-Shan Cheng, Manisha Pradhan, Jizhong Zou, Jeanette Beers, Wei Zheng

Keywords(s): Cell, COMPOUND, DERIVED, Disease, iPS, Lines, Lysosomal, Modeling, PATIENT, screening, Storage, VPXXXX, WIXXXX, XHXXXX

Category(s): TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Ophthalmology, TherapeuticArea > Dental, TherapeuticArea > Oncology, TherapeuticArea > Endocrinology, Application > Research Materials, ResearchProducts > Research Equipment

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 3/15/2023 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

Tetrazole & Coumarin Phosphonate Based Broad-Spectrum Beta-Lactamase Inhibitors

Competitive Advantages Combats bacterial antibiotic resistance to β-Lactamase Effectively inhibits against the different classes of β-Lactamase Enhances effectiveness of current β-lactam antibiotics treatments Summary Our inventors have discovered tetrazole and coumarin phosphonate based compounds can actively inhibit...

Published: 6/27/2024 | Inventor(s): Yu Chen, Orville Pemberton, Adam Renslo, Priyadarshini Jaishankar

Keywords(s): Infectious Diseases Treatment, Pharmaceuticals

Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical

Beta-Lactamase Inhibitor Compositions, Methods of Use, and Methods of Treatment

Competitive Advantages Can restore the efficacy of beta-lactam antibiotics Overcomes antibiotic resistance May help to develop new antibiotic treatment regimens Treats multi-drug resistant organisms Summary Our researchers have developed compositions comprised of a beta-lactamase inhibitor and methods of use to treat various infections and...

Published: 6/27/2024 | Inventor(s): Adam Renslo, Derek Nichols, Priyadarshini Jaishankar, Yu Chen, Erica Lauterwasser

Keywords(s): Infectious Diseases Treatment, Pharmaceuticals

Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical

2015-671 Underground Shafts for Hydrogen Storage

SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...

Published: 7/19/2023 | Inventor(s): Adrienne Lavine, Hossein Kavehpour, Dante Simonetti, Richard Wirz, Chen Chen, Gabriela Bran, Gopinath Warrier, Hamarz Aryafar, Jonathon Kennedy, Joshua Jordan, Keith Lovegrove

Keywords(s): Energy & Water

Category(s): Energy & Environment > Energy Generation > Solar, Energy & Environment > Energy Storage

Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy

The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...

Published: 4/19/2023 | Inventor(s): Jianming Liang, Yu An, Wei Liu

Keywords(s):

Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging

ODD: Protecting Sensitive Data in Mobile Devices by Out-of-order Data Division

A novel, multi-layer distributed data security scheme that provides a triple layer of out-of-order divide and store protection of data Background: Technologists are looking to achieve a balance between making data difficult to be illegally or maliciously compromised while providing legitimate data users and owners sufficient encryption protection...

Published: 8/3/2021 | Inventor(s): Yu Chen

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Wireless Technologies, Technology Classifications > Computers, Campus > Binghamton University