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Search Results - yu-min+chen
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A novel approach to enhance efficiency, stability, and reliability of perovskite solar cells (PSCs) simultaneously
Perovskite Solar Cells with Self Assembled Monolayers Overview This technology describes a novel approach to improving the mechanical reliability and performance of perovskite solar cells (PSCs) through the use of halide-terminated self-assembled monolayers (halide-SAMs) as molecular "glue" between different layers of the solar cell. The...
Published: 6/24/2025
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Inventor(s):
Nitin Padture
,
Zhenghong Dai
,
Srinivas Yadavalli
,
Min Chen
Keywords(s):
Category(s):
Engineering and Sensors
,
Energy
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025
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Inventor(s):
Stephen Liggett
,
Donghwa Kim
,
Yu Chen
,
Jesper Madsen
,
Steven An
Keywords(s):
Pharmaceuticals
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
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Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation
Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...
Published: 10/2/2023
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Inventor(s):
Yu Chen
,
Michael Sacco
,
James Leahy
,
Elena Bray
,
Xingmin Sun
,
Xiujun Zhang
Keywords(s):
Drug Discovery
,
Infectious Diseases Treatment
Category(s):
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
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Technology Classifications > Medical > Medical Diagnostics
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Technology Classifications > Medical > Infectious Diseases
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Technology Classifications > Medical > Biotechnology
Nanopore Tweezer System for Protein Kinase Allosteric Drug Screening
PRODUCT OPPORTUNITIES AND END-USE APPLICATIONS • Nanopore-tweezer-based system for efficient kinase allosteric drug screening ADVANTAGES • Label-free method • Capable of identifying both allosteric inhibitors and activators • Capable of distinguishing active-site inhibitors from allosteric...
Published: 8/3/2023
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Inventor(s):
Min Chen
,
Fanjun Li
Keywords(s):
Category(s):
Biotechnology
,
Life Sciences
,
Research tools
Nanopore-based Sensors for Antibody Screening Applications
PRODUCT OPPORTUNITIES AND END-USE APPLICATIONS • Nanopore-based antibody screening system • Nanopore sensors for antibody detection and identification • Antibody screening in hybridoma-based antibody production • Real-time monitoring of antibody production in cell culture ADVANTAGES •...
Published: 6/26/2023
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Inventor(s):
Min Chen
,
Joshua Foster
,
Minji Kim
,
Matthew Moore
Keywords(s):
Category(s):
Devices & sensors
,
Life Sciences
,
Research tools
Novel Multi-Omics Aging Clock
A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...
Published: 3/12/2024
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Inventor(s):
George Sutphin
,
Samuel Freitas
,
Megha Padi
,
Chen Chen
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Biomarkers
,
Technology Classifications > Research Tools > Animal Models
,
Technology Classifications > Research Tools > Screening assays
,
Technology Classifications > Research Tools > Simulators and Modeling Tools
Autonomous Drone for railroad track inspection
Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...
Published: 3/28/2025
|
Inventor(s):
Yu Qian
,
Yi Wang
,
Chen Chen
Keywords(s):
autonomous drone
,
flight control
,
image processing
,
railroad track inspection
,
self-navigation
Category(s):
Engineering and Physical Sciences
Tetrazole & Coumarin Phosphonate Based Broad-Spectrum Beta-Lactamase Inhibitors
Competitive Advantages Combats bacterial antibiotic resistance to β-Lactamase Effectively inhibits against the different classes of β-Lactamase Enhances effectiveness of current β-lactam antibiotics treatments Summary Our inventors have discovered tetrazole and coumarin phosphonate based compounds can actively inhibit...
Published: 6/27/2024
|
Inventor(s):
Yu Chen
,
Orville Pemberton
,
Adam Renslo
,
Priyadarshini Jaishankar
Keywords(s):
Infectious Diseases Treatment
,
Pharmaceuticals
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical
Beta-Lactamase Inhibitor Compositions, Methods of Use, and Methods of Treatment
Competitive Advantages Can restore the efficacy of beta-lactam antibiotics Overcomes antibiotic resistance May help to develop new antibiotic treatment regimens Treats multi-drug resistant organisms Summary Our researchers have developed compositions comprised of a beta-lactamase inhibitor and methods of use to treat various infections and...
Published: 6/27/2024
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Inventor(s):
Adam Renslo
,
Derek Nichols
,
Priyadarshini Jaishankar
,
Yu Chen
,
Erica Lauterwasser
Keywords(s):
Infectious Diseases Treatment
,
Pharmaceuticals
Category(s):
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical
2015-671 Underground Shafts for Hydrogen Storage
SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...
Published: 2/14/2025
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Inventor(s):
Adrienne Lavine
,
Hossein Kavehpour
,
Dante Simonetti
,
Richard Wirz
,
Chen Chen
,
Gabriela Bran
,
Gopinath Warrier
,
Hamarz Aryafar
,
Jonathon Kennedy
,
Joshua Jordan
,
Keith Lovegrove
Keywords(s):
Energy & Water
Category(s):
Energy & Environment > Energy Generation > Solar
,
Energy & Environment > Energy Storage
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