Search Results - life+sciences

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A multiplexed CRISPR genome editing platform for simultaneous gene disruption in neurons
SPADA is a CRISPR-based genome editing system that uses engineered viruses to efficiently and specifically disrupt multiple genes in targeted brain cells, enabling precise modeling of complex genetic brain disorders in animals. Background The field of neurogenetics relies heavily on genome editing to understand the mechanisms of complex psychiatric...
Published: 4/28/2026   |   Updated: 4/27/2026   |   Inventor(s): Lief Fenno, Yeonha Ju
Keywords(s):  
Category(s): Life sciences, Life sciences > Research tools > Tool/assay/screening platform
Anti-CD160 Humanized Antibody
Engineered humanized anti-CD160 antibodies and derivatives for depleting CD160+ immune cells to attenuate inflammation Background: Adaptive immune responses contribute significantly to the progression of acute myocarditis, where overactivation of cytotoxic lymphocytes leads to myocardial injury and eventual heart failure. Targeting immune receptors...
Published: 2/17/2026   |   Updated: 2/17/2026   |   Inventor(s): Jennifer Maynard, Agata Turula
Keywords(s):  
Category(s): Life sciences, Life sciences > Therapeutics > Biologic
Kulkarni/ Sprayable polymeric scaffold loaded with inflammasome-inhibiting lipid nanorods for anti-inflammatory therapy
­PRODUCT OPPORTUNITIES •Topical treatment for Psoriasis & Inflammatory Skin Conditions •Advanced drug delivery solutions PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES •Sprayable formulation ensures easy application, even distribution, improving adherence and convenience •​​​​​​​Targeted therapy with...
Published: 12/24/2025   |   Updated: 12/24/2025   |   Inventor(s): Ashish Kulkarni, Dhanashree Surve
Keywords(s):  
Category(s): Healthcare, Material science, Nanotechnology, Therapeutics & prevention, Life Sciences
Food-Grade Antioxidants and Methods of Preparation Thereof
PRODUCT OPPORTUNITIES• Natural, food-grade antioxidants as food additives• Lipid-containing food products with extended shelf lifePRODUCT OPPORTUNITIESADVANTAGES• Natural and food-grade antioxidants• Value added products (antioxidants) made from naturally derived lecithin• Low cost production•...
Published: 10/1/2025   |   Updated: 10/1/2025   |   Inventor(s): Eric Decker
Keywords(s):  
Category(s): Food technology & plant science, Life Sciences
Demineralized Bone Paper and Applications Thereof
PRODUCT OPPORTUNITIES • Three-dimensional, living bone tissue grafts produced from stacked demineralized bone paper (DBP) for clinical applications • DBP-based high-throughput and high-content assay systems for bone disease drug discovery • Other DBP-containing products such as microfluidic bone marrow chips PRODUCT...
Published: 4/20/2026   |   Updated: 10/1/2025   |   Inventor(s): Jungwoo Lee, Jae-Hyuck Shim, Ryan Carpenter, Yongkuk Park, Jun-Goo Kwak
Keywords(s):  
Category(s): Biotechnology, Devices, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
An Ex Vivo Method of Generating Super Regulatory T Cells as a Cell-based Therapy for the Prevention of Graft-vs-Host Disease
PRODUCT OPPORTUNITIES • Cell-based therapy for the prevention of graft-versus-host disease ADVANTAGES • Simple, well-defined generation of personalized, cell-based therapy for the prevention of graft-versus-host disease • Generation of super regulatory T cells with greatly improved suppressive capacity. TECHNOLOGY...
Published: 9/25/2025   |   Updated: 9/25/2025   |   Inventor(s): Lisa Minter, Gregory Tew, Emrah Ozay
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
Thread-Enabled Mobile IoT Network
Summary: Flying robots, i.e., drones, are being implemented to help solve various day-to-day challenges. The global drone market is significantly growing and is predicted to be 279 billion U.S. dollars by 2032. In recent years, drones have spurred interest in Internet-of-Things (IoT) applications, thereby serving as a key enabler for various critical...
Published: 7/1/2025   |   Updated: 7/1/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Agriculture, Life Sciences, Engineering & Physical Sciences, Sensors & Controls
Electrochemical biosensor for detection of chronic wasting disease
Summary: This invention is a microelectrochemical sensing device that detects the agent of chronic wasting disease. Chronic wasting disease is a prion disease, caused by a misfolded prion protein (PrPSc). Mammals normally express the healthy prion protein (PrPC). The disease associated form (PrPSc) has the same nucleic acid sequence - making accurate...
Published: 7/1/2025   |   Updated: 7/1/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Agriculture, Life Sciences, Veterinary Medicine, Engineering & Physical Sciences, Medical Devices, Sensors & Controls, Research Tools & Design Tools
Decorating Microbially Produced Protein Nanowires with Peptide Ligands
­PRODUCT OPPORTUNITIES • Sensors/Biosensors • Sustainable electronics PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES • Expand possibilities for attaching electronically conductive protein nanowires (e-PNs) to substrates • Enhance binding of desired analytes for sensors • Enable covalent bonding of e-PNs...
Published: 4/25/2025   |   Updated: 4/25/2025   |   Inventor(s): Derek Lovley, Toshiyuki Ueki
Keywords(s):  
Category(s): Devices & sensors, Life Sciences
A general strategy for synthesizing molecularly functionalized biomass for atmospheric water harvesting
Background Water scarcity remains a pressing global challenge, and conventional atmospheric water harvesting methods often struggle to balance efficiency with environmental sustainability. Existing technologies frequently rely on synthetic polymers or salt‐polymer hybrids that exhibit issues such as limited water uptake under low relative humidity,...
Published: 1/13/2026   |   Updated: 4/23/2025   |   Inventor(s): Guihua Yu, Weixin Guan, Yaxuan Zhao
Keywords(s):  
Category(s): Physical sciences > Environmental & sustainable solutions > Water, Physical sciences > Materials, Life sciences, Life sciences > Agriculture
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