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Search Results - life+sciences
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Tools for Genomic Applications Powered by CRISPR/CAS9 Based DNA Labeling
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Drexel has a portfolio of tools and platforms for genomics applications based on the CRISPR/CAS9 system. The portfolio has applications in clinical diagnostics, cell and gene therapy, and genomics research among others. We are seeking licensing partners to translate the platforms and diagnostic...
Published: 8/5/2024
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Inventor(s):
Keywords(s):
Category(s):
Life Sciences
,
Medical Devices & Diagnostics > MDD: Diagnostic Tests
,
Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy
,
Pharmaceuticals & Therapeutics > Pharma: Gene Therapy
,
Pharmaceuticals & Therapeutics > Pharma: Genome Engineering
,
Pharmaceuticals & Therapeutics > Pharma: Oncology
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Research Tools & Materials
Fusion protein technology for site‑specific integration of RNA into DNA genomes
The technology integrates target RNA into DNA genomes by adding short DNA tails to RNA. Direct RNA integration into CRISPR arrays eliminates the use of harsh transfection methods that fragment DNA sequences. Background The development of CRISPR-Cas systems, which are widely used for precise genetic modifications, has advanced the field of genome...
Published: 7/25/2024
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Inventor(s):
Alan Lambowitz
,
Georg Mohr
Keywords(s):
Category(s):
Life sciences
,
Life sciences
> Therapeutics > Gene editing
Biomimetic aggrecan injection for lower back pain treatment
PAGE TITLE Overview PAGE SUMMARY Proteoglycans (PGs) are a major building block and a hydrating agent in the extracellular matrix, which maintains structural organization of cells within tissues. PGs retain water and regulate flow of minerals and other nutrients, lubricate and provide mechanical support to the tissues. The combination of PGs and...
Published: 7/16/2024
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Inventor(s):
Michele Marcolongo
,
Caroline Schauer
,
Sumona Sarkar
,
Edward Vresilovic
,
Benjamin Jackson
Keywords(s):
Aggrecan
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Biomaterial
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Biomimetic
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Degenerative disc disease
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Injectable
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Lower back pain
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Minimally Invasive
,
Spine
Category(s):
Life Sciences
,
Medical Devices & Diagnostics
Non-invasive quantitative monitor of depth of anesthesia and sedation
PAGE TITLE Overview PAGE SUMMARY Drexel researchers have developed a non-invasive device for quantitative, real-time monitoring of the depth of anesthesia both during general anesthesia in surgery and sedation in endoscopy and colonoscopy procedures. The device uses functional near-infrared (fNIR) spectroscopy to measure physiological parameters...
Published: 7/16/2024
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Inventor(s):
Kambiz Pourrezaei
,
Kurtulus Izzetoglu
,
Banu Onaral
,
Jay Horrow
,
Scott Bunce
,
Meltem Izzetoglu
Keywords(s):
NIR - near infrared
Category(s):
Life Sciences
,
Medical Devices & Diagnostics
Low-cost manufacturing of highly sensitive label-free molecular detection substrates
PAGE TITLE Overview PAGE SUMMARY Label-free detection and characterization of molecules is an important tool for detecting a composition of a substance, be it a water, soil, chemical product or biological sample. Its main advantage is the ability to measure quantities of different molecules without knowing their identity in advance. Examples...
Published: 7/16/2024
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Inventor(s):
Som Tyagi
,
Kambiz Pourrezaei
Keywords(s):
Category(s):
Life Sciences
,
Medical Devices & Diagnostics
,
Physical Sciences
,
Mechanical & Civil Engineering
An integrated sensing chip for attomolar label-free detection of amplified nucleic acids
Summary: Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification technique and has been widely used for detection of pathogens in many organisms. Current LAMP-based sensors usually require the LAMP products to be labeled in order for them to be detected. Description: This new LAMP chip offers a new portable platform to detect...
Published: 7/2/2024
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Inventor(s):
Keywords(s):
Category(s):
Agriculture
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Engineering & Physical Sciences
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Sensors & Controls
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Research Tools & Design Tools
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Medical Devices
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Veterinary Medicine
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Life Sciences
,
Healthcare
The Power of Food Scale: A Tool to Evaluate the Psychological impact of the Food Environment Factors that Affect Appetite
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Hunger in humans is driven by basic internal factors like nutritional or caloric deficit but also by external factors like the food environment. as well as more complex behaviors driven by pleasure or desire. The Power of Food Scale (PFS) is a validated measure of hedonic hunger, the...
Published: 6/12/2024
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Inventor(s):
Michael Lowe
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics > Pharma: Metabolic
,
Life Sciences
enAble Games
PAGE TITLE Company Background PAGE SUMMARY enAble Games was created to offer an innovative suite of active video games (AVG) to support physical therapy for children and adults with cerebral palsy and other neuromuscular conditions. It was founded by Drexel University professors in Digital Media and Physical Therapy bringing their knowledge and...
Published: 5/16/2024
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Inventor(s):
Keywords(s):
Category(s):
Startup Companies
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Life Sciences
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Medical Devices & Diagnostics
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Computing, Software, Analytics & Information Technology
Artificial Reproduction Technique
PRODUCT OPPORTUNITIES Novel method to treat sperm for artificial reproduction Artificial reproductive kit PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Improve functionality and/or fertility of sperm Reduces the number of sperm needed for insemination Improve conception rates...
Published: 5/3/2024
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Inventor(s):
Pablo Visconti
,
Felipe Navarrete
Keywords(s):
Category(s):
Biotechnology
,
Life Sciences
,
Veterinary science
Stretchable hybrid response pressure sensor
Background Electronic skins, e-skins for short, is innovative soft electronics technology that gives robots and devices tactile sensing capabilities like human touch and feel. Robots equipped with human touch sensitivity could be deployed in many different applications ranging from manufacturing and food handling/preparation to medical care and surgery,...
Published: 6/28/2024
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Inventor(s):
Nanshu Lu
,
Kyoung-Ho Ha
Keywords(s):
Category(s):
Life sciences
> Medical technology
,
Life sciences
,
Life sciences
> Biomaterials
,
Computer software > Digital health
,
Computer software > Robotics
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