Search Results - ying+zhang

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Targeted Therapy for Triple-Negative Breast Cancer
Breast cancer is the second leading cause of death in women and is the most common cancer among women worldwide. There are four main breast cancer subtypes, luminal A, luminal B, HER2-positive and triple-negative. Triple-negative breast cancer (TNBC) is highly invasive and has higher rates of metastasis and a worse prognosis. Metastasis of cancer cells...
Published: 9/12/2023   |   Inventor(s): Shengxi Chen, Xiaojiang Cui, Yi Zhang, Sidney Hecht
Keywords(s):  
Category(s): Life Science (All LS Techs), Advanced Materials/Nanotechnology, Cancer, Cancer Therapeutics, Pharmaceuticals
Photonic FPGA platform to create arbitrary photonic devices by programming the device structure into the platform.
Background The development and design process for electronic integrated circuits is very intensive before a finalized chip design is sent to the chip fab. Most application-specific electronic integrated circuits require a prototyping process that can be accomplished with a field-programmable gate array (FPGA), an electronic circuit which can be reconfigured...
Published: 5/7/2024   |   Inventor(s): Jaime Cardenas Gonzalez, Yi Zhang, Marissa Granados-Baez
Keywords(s):  
Category(s): Nanotechnology
Imaging Inflammation using PET Radioligands that Target Translocator Protein 18?kDa with High Affinity Regardless of Genotype
This technology includes a group of radioligands that label inflammatory cells specifically, accurately, and across different genotypes and can be detected using Positron Emission Tomography (PET). The radioligands target the Translocator protein 18 kDa (TSPO) receptor which is present on the outer mitochondrial membrane and is involved in the production...
Published: 7/25/2024   |   Inventor(s): Robert Innis, Federico Da Settimo, Giorgio Stefancich, Sabrina Taliani, Sabrina Castellano, Claudia Martini, Yi Zhang, Victor Pike
Keywords(s): 18kDa, Emission, Genotype, Human, Listed LPM Fenn as of 4/15/2015, NA1XXX, Positron, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Quantifying/imaging, Radioligands, Regardless, tomography, TSPO, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX
Category(s): TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Neurology, Application > Software / Apps, Application > Diagnostics, Application > Medical Devices, Application > Research Materials
Neutralizing Antibodies to Influenza HA and Their Use and Identification
The effectiveness of current influenza vaccines varies by strain and season, in part because influenza viruses continuously evolve to evade human immune responses. While the majority of seasonal influenza infections cause relatively mild symptoms, each year influenza virus infections result in over 500,000 hospitalizations in the United States and Europe....
Published: 7/25/2024   |   Inventor(s): Robert Bailer, Michael Joyce, John Mascola, Peter Kwong, Sarah Andrews, Paul Thomas, Gwo-Yu Chuang, Adam Wheatley, Yi Zhang, James Whittle, Adrian McDermott
Keywords(s): 1, 2, antibodies, DB4XXX, DBXXXX, DC5XXX, DCXXXX, DXXXXX, GROUP, INFLUENZA, Neutralize, That, Their, Viruses, VLXXXX, WJXXXX, WNXXXX, XAXXXX, XKXXXX, YCXXXX
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease, ResearchProducts > Antibodies, TherapeuticArea > Immunology
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023   |   Inventor(s): Leilei Peng, Yu Li, Han Zhang
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Fibrosis-free microfluidic meshwork implant for treating glaucoma
BackgroundGlaucoma is the leading cause of irreversible blindness in the world and affects almost three million people in the United States alone. The primary treatment option is to reduce the intraocular pressure (IOP) caused by fluid buildup in the affected eye, which is frequently accomplished by surgery to create an outflow of the accumulated fluid....
Published: 6/17/2024   |   Inventor(s): Chong Xie, Lan Luan, Ying Han
Keywords(s): Medical devices, Ophthalmic surgery, Ophthalmology
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Therapeutics > Synthetic biology
Method to enhance formation of nano-features in soft lithography
Technology Overview: Soft lithography uses a patterned elastomer polydimethylsiloxane (PDMS) as the stamp or mold to generate micro- and nano-patterns. This method is limited for features smaller than 100 nm, as the low modulus PDMS may deform and result in pattern collapse and rounded corners. Penn scientists have developed a novel method to form...
Published: 10/16/2023   |   Inventor(s): Shu Yang, Ying Zhang, Randall Kamien, James Kikkawa, Dinesh Chandra, Elisabetta Matsumoto
Keywords(s): Nanotechnology
Category(s): Technology Classifications > Research Tools & Reagents