Search Results - technology+classifications+%3e+materials

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Quick, Scalable, and Precise Method to Produce Uniform Superparticles for Optical and Magnetic Applications
A method to cluster nanocrystals into uniform superparticles using a source-sink emulsion system. Problem: Superparticles present a compelling platform for customizable microscale magnets, sensors, and lasers. However, current manufacturing processes are slow, expensive, and imprecise resulting in loosely packed and polydisperse superparticles. Existing...
Published: 1/28/2025   |   Inventor(s): Emanuele Marino, Sjoerd van Dongen, Thomas Kodger, Christopher Murray
Keywords(s): Electronic Materials, Nanotechnology, Optics & Photonics 
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
Composite Filament for 3D Printing of Resorbable Bone Scaffolds
This innovation is composite filaments for 3D printing bioresorbable scaffolds for surgical implantation. These filaments typically have high strength, an appropriate resorption rate, and high biocompatibility. The resulting scaffolds offer customizable shapes and resorption rates. The improvement in this innovation compromises a bone volume fraction...
Published: 1/16/2025   |   Inventor(s): John Szivek, Luis Arciniaga, Douglas Loy, David Margolis
Keywords(s):  
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Medical Devices, Technology Classifications > Sensors & Controls, Technology Classifications > Software & Information Technology, Technology Classifications > Materials
Macrophage-Targeting Lipid Nanoparticles (MacLNPs) Deliver siRNA Intranasally to Treat Viral Pneumonia
siRNA-LNP knock-down of TAK1 delivered intranasally and to macrophages specifically prevents inflammation-induced pathology in a mouse model Problem: Macrophages are an important component of the innate immune system, but can mediate excessive inflammation and cause severe pathology if left unchecked. This poses a challenge for the treatment of acute...
Published: 12/19/2024   |   Inventor(s): Michael Mitchell, Lulu Xue, Andrew Vaughan, Gan Zhao
Keywords(s): Bioengineering, Drug Delivery, Gene Therapy, Immunology, Infectious Disease, Inflammation, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Therapeutics, Technology Classifications > Vaccines
Bilayer Solid-State Nanopores for the Tracking, Filtering and Guiding of DNA
A bilayered solid-state nanopore material that senses and guides DNA and other biomolecules into homogeneous configurations. Problem: Current methods of DNA sensing and sequencing typically involve short read lengths, chemical labeling, labor-intensive sample preparation, and lack of portability. To minimize these issues during DNA sequencing, protein-based...
Published: 11/25/2024   |   Inventor(s): Marija Drndic, Yung-Chien Chou, Dimitrios Monos, Chih-Yuan Lin
Keywords(s): Nanotechnology
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
Adhesive Microparticle Formulation For Localized And Sustained Drug Delivery
A hairy, water-in-oil-in-water microemulsion for prolonged delivery of one or more active ingredients while adhering to target tissues. Problem: Microparticles are promising drug delivery platforms due to their biocompatibility and stability. However, existing particle-based drug delivery systems are unable to fulfill the needs for prolonged delivery...
Published: 1/17/2025   |   Inventor(s): Daeyeon Lee, Minjun Oh, Jaehyun Kim, Li-Wei Chang, Robert Mauck, George Dodge, Hyun (Michel) Koo
Keywords(s): Bioengineering, Dentistry, Drug Delivery, Drug Target
Category(s): Technology Classifications > Materials
Fluid Additives for Enhanced Magnetorheological Fluid Performance
­The Problem: Magnetorheological fluids (MRFs) are a type of smart or controllable fluid that can change their flow-related properties in response to an applied magnetic field. MRFs have significant potential as absorbers and dissipaters for mitigating earthquake damage, in prosthetic applications, and in robotics. However, their widespread use...
Published: 11/5/2024   |   Inventor(s): Amanda Koh, Emmanual Johnson, Sandhiya Thiagarajan
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Materials, Technology Classifications > Healthcare, Technology Classifications > Lifestyle & Leisure, Technology Classifications > Manufacturing
Crosslinkable Resins from Glycerol-Derived Compounds
The Problem: The integration of plastic waste in crosslinkable resin production remains underexplored, representing a significant missed opportunity for promoting recycling and waste management. Conventional crosslinkable resin production methods often rely on expensive and non-renewable raw materials, limiting scalability and scope of application....
Published: 11/5/2024   |   Inventor(s): Jason Bara, Mousumi Rani Bepari
Keywords(s):  
Category(s): Technology Classifications > Materials, Technology Classifications > Manufacturing
An iron oxide nanozyme formulation for augmenting the efficacy of oral care products.
A combinatory formulation for oral care products that enhances antimicrobial specificity, anti-plaque potency and prevents tooth decay. Problem: Tooth decay (dental caries), caused by the destruction of the outer layer (enamel) of teeth by bacteria in biofilms, affects nearly half of the global population and remains the most prevalent chronic disease...
Published: 10/8/2024   |   Inventor(s): Yue Huang, Hyun (Michel) Koo, David Cormode
Keywords(s): Bioengineering, Dentistry, Infectious Disease, Microbiome, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Therapeutics
Adjuvanted Lipid Nanoparticles (LNPs) Enhance Protective Immunity Imparted by SARS-CoV-2 mRNA Vaccine
A lipid nanoparticle formulation that elicits a strong innate immune response for improved vaccine protection Problem: Lipid nanoparticle (LNP)-formulated mRNA vaccines have revolutionized modern vaccinology through their ability to deliver mRNA vaccines with remarkable manufacturing flexibility. However, the modified (pseudouridylated) mRNA used in...
Published: 10/1/2024   |   Inventor(s): Michael Mitchell, Xuexiang Han, Drew Weissman, Mohamad Alameh
Keywords(s): Bioengineering, COVID-19, Drug Delivery, Immunology, Infectious Disease, Nanotechnology
Category(s): Technology Classifications > Materials, Technology Classifications > Vaccines
SNMF – An On-the-Fly, Multi-Filament Single-Nozzle for 3D Printing
A printing system with a single nozzle/printhead that can dispense multiple materials in a controlled manner. Problem: Multi-material additive manufacturing transcends the limitations of traditional manufacturing processes by allowing the fabrication of complex, functionally graded components with tailored material properties. However, limitations remain...
Published: 1/17/2025   |   Inventor(s): Masoud Akbarzadeh, Teng Teng, Yefan Zhi
Keywords(s):  
Category(s): Technology Classifications > Design and Multimedia, Technology Classifications > Hardware & Components, Technology Classifications > Materials
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