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Fluid Additives for Enhanced Magnetorheological Fluid Performance
­The Problem: Magnetorheological fluids (MRFs) are a type of smart or controllable fluid that can change their flow-related properties in response to an applied magnetic field. MRFs have significant potential as absorbers and dissipaters for mitigating earthquake damage, in prosthetic applications, and in robotics. However, their widespread use...
Published: 11/5/2024   |   Inventor(s): Amanda Koh, Emmanual Johnson, Sandhiya Thiagarajan
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Materials, Technology Classifications > Healthcare, Technology Classifications > Lifestyle & Leisure, Technology Classifications > Manufacturing
Crosslinkable Resins from Glycerol-Derived Compounds
The Problem: The integration of plastic waste in crosslinkable resin production remains underexplored, representing a significant missed opportunity for promoting recycling and waste management. Conventional crosslinkable resin production methods often rely on expensive and non-renewable raw materials, limiting scalability and scope of application....
Published: 11/5/2024   |   Inventor(s): Jason Bara, Mousumi Rani Bepari
Keywords(s):  
Category(s): Technology Classifications > Materials, Technology Classifications > Manufacturing
An iron oxide nanozyme formulation for augmenting the efficacy of oral care products.
A combinatory formulation for oral care products that enhances antimicrobial specificity, anti-plaque potency and prevents tooth decay. Problem: Tooth decay (dental caries), caused by the destruction of the outer layer (enamel) of teeth by bacteria in biofilms, affects nearly half of the global population and remains the most prevalent chronic disease...
Published: 10/8/2024   |   Inventor(s): Yue Huang, Hyun (Michel) Koo, David Cormode
Keywords(s): Bioengineering, Dentistry, Infectious Disease, Microbiome, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Therapeutics
Adjuvanted Lipid Nanoparticles (LNPs) Enhance Protective Immunity Imparted by SARS-CoV-2 mRNA Vaccine
A lipid nanoparticle formulation that elicits a strong innate immune response for improved vaccine protection Problem: Lipid nanoparticle (LNP)-formulated mRNA vaccines have revolutionized modern vaccinology through their ability to deliver mRNA vaccines with remarkable manufacturing flexibility. However, the modified (pseudouridylated) mRNA used in...
Published: 10/1/2024   |   Inventor(s): Michael Mitchell, Xuexiang Han, Drew Weissman, Mohamad Alameh
Keywords(s): Bioengineering, COVID-19, Drug Delivery, Immunology, Infectious Disease, Nanotechnology
Category(s): Technology Classifications > Materials, Technology Classifications > Vaccines
SNMF – An On-the-Fly, Multi-Filament Single-Nozzle for 3D Printing
A printing system with a single nozzle/printhead that can dispense multiple materials in a controlled manner. Problem: Multi-material additive manufacturing transcends the limitations of traditional manufacturing processes by allowing the fabrication of complex, functionally graded components with tailored material properties. However, limitations remain...
Published: 8/26/2024   |   Inventor(s): Masoud Akbarzadeh, Teng Teng, Yefan Zhi
Keywords(s):  
Category(s): Technology Classifications > Design and Multimedia, Technology Classifications > Hardware & Components, Technology Classifications > Materials
3D Printable, Lightweight, High-Strength Concrete for Carbon Capture and Storage
The formulation replaces up to 50 weight percent of ordinary Portland cement (OPC) with the highly porous, biomineral, diatomaceous earth. Problem: Concrete is the world’s second-most-used material, and its production process is carbon-intensive, contributing significantly to greenhouse gas emissions. One promising solution is carbon capture and...
Published: 8/26/2024   |   Inventor(s): Shu Yang, Kun-Hao (Ted) Yu
Keywords(s):  
Category(s): Technology Classifications > Materials
Dye-Loaded Micelles for Direct Visualization of Colorectal Cancer
A tissue-selective, biocompatible contrast agent enables the visual identification of tumors and tumor margins during procedures Problem: Dye-based chromoendoscopy (DBC) helps endoscopists visualize colorectal mucosa and identify inflammatory polyps that could progress toward colorectal cancer in patients with inflammatory bowel disease (IBD). However,...
Published: 8/2/2024   |   Inventor(s): Andrew Tsourkas, Ahmad Amirshaghaghi, Zhiliang Cheng, Karthik Sundaram, Yiran Tian
Keywords(s): Bioengineering, Imaging Agents, Nanotechnology, Oncology, Surgery
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Materials
Scalable, Low Voltage Device For Liquid Crystal-Based Technologies
A multi-stable liquid crystal (LC) device based on saddle-spray director variation that enables fast optoelectronic switching and has low power requirements. Problem: LC devices are crucial for a number of modern technologies including monitors, electronic switches, and storage devices. These devices rely on an optoelectrical process by which applied...
Published: 7/30/2024   |   Inventor(s): Shu Yang, Yu Xia, Timothy Atherton, Douglas Cleaver, Andrew DeBenedictis, DaeSeok Kim
Keywords(s): Optics & Photonics 
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Materials
Biocompatible, Reversible, and Strong Multilayered Tape for Advanced Wound Care
A hydrogel-based adhesive with a hydrophobic backing layer protects it from exposure to water and offers painless removal and easy repositioning. Problem: Reversible adhesives have gained popularity in industries with a growing emphasis on reducing waste and improving sustainability. Previously, the inventors have developed a strong and reversible adhesive...
Published: 7/23/2024   |   Inventor(s): Shu Yang, Baohong Chen, Alexander Tucker
Keywords(s): Bioengineering, Hydrogels, Platform Technology, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials
Effective Anti-Fouling Surface Coating of Microfluidic Mixing Devices for Robust mRNA Lipid Nanoparticles (LNP) Manufacturing
Employment of omniphobic, thin-layer perfluorocarbon (TLP) coating to prevent fouling and clogging in microfluidic mixing devices during mRNA LNP formulations. Problem: Lipid nanoparticle (LNP)-based delivery systems for mRNA and other therapeutics recently gained popularity because of their application in the Pfizer/BioNTech and Moderna COVID-19 vaccines....
Published: 7/15/2024   |   Inventor(s): Daeyeon Lee, Yoon-Ho Hwang, David Issadore
Keywords(s): Bioengineering, Microfluidics
Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Materials
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