Search Results - marija+drndic

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Bilayer Solid-State Nanopores for the Tracking, Filtering and Guiding of DNA
A bilayered solid-state nanopore material that senses and guides DNA and other biomolecules into homogeneous configurations. Problem: Current methods of DNA sensing and sequencing typically involve short read lengths, chemical labeling, labor-intensive sample preparation, and lack of portability. To minimize these issues during DNA sequencing, protein-based...
Published: 11/25/2024   |   Inventor(s): Marija Drndic, Yung-Chien Chou, Dimitrios Monos, Chih-Yuan Lin
Keywords(s): Nanotechnology
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
Graphene nanopore devices to monitor DNA translocations
Technology Overview: This invention is a fabrication method to generate a 1−5 nm thick graphene membrane on top of a silicon nitride window. The membrane is then drilled with transmission electron beam ablation lithography to create nanopores that are 5 to 10 nm in diameter. Graphene nanopore devices offer better performance than other methods...
Published: 1/25/2024   |   Inventor(s): Marija Drndic
Keywords(s):  
Category(s): Technology Classifications > Research Tools & Reagents
Solid state nanopore DNA sequencing
Problem: Existing sequencing processes require DNA to be copied millions of times and labelled with fluorescent tags. This procedure can require eight days of processing time at a cost of thousands of dollars. The slow and expensive process presents a barrier to screening patients’ genomes and inhibits the rise of personalized medicine. Solution:...
Published: 1/25/2024   |   Inventor(s): Marija Drndic
Keywords(s): Nanotechnology
Category(s): Technology Classifications > Research Tools & Reagents, Technology Classifications > Materials
Solid-state nanopore membranes for DNA detection and sequencing
A technology portfolio comprising fabrication and detection methods for improved DNA sequencing using nanoporous membranes. Technology Overview: This technology portfolio consists of fabrication methods for generating ultra-thin Silicon Nitride (SiN) membranes and ultra- low capacity, glass supported dielectric membranes for DNA sequencing. Ultra-thin...
Published: 1/31/2024   |   Inventor(s): Marija Drndic
Keywords(s):  
Category(s): Technology Classifications > Materials