New Device Material for a Flexible Chronic Implantable Neural Interface

­Advantages:

  • Superior biocompatibility reduces immune responses.
  • Excellent electrical conductivity enhances signal transmission.
  • Exceptional mechanical strength enables durable and flexible probes.

Summary:

Implantable neural interfaces (INIs) are devices configured to connect with the human nervous system through electrical means. Such devices allow electrical recording and stimulation of the nervous system and may contribute to developing effective treatments for various nervous system diseases (e.g. depression, addiction, Parkinson's, Alzheimer's and poliomyelitis). Existing materials used in neural interfaces often degrade over time, trigger immune responses, and lead to neuronal loss, driving the need for innovative solutions.

Carbon-based nanomaterials like graphene, carbon nanotubes, and pyrolyzed-photoresist films (PPF) offer compelling alternatives due to their superior electrical conductivity and mechanical properties. These materials present a significant market opportunity for developing more durable and biocompatible neural probes. The neural interface incorporating amorphous silicon carbide and PPF represents a standout solution, offering robustness, thinness, and flexibility—all crucial features in meeting the market demand for advanced neuro-compatible devices. Embracing this technology can fuel healthcare innovation by addressing critical requirements for enhanced neural interface performance and longevity.

 

 (a) Photograph of a completely fabricated 16 channel C-based electrode on flexible a-SiC. Bonding pads on left of image. (b) CV measurement of C electrode demonstrating superior performance to a control platinum electrode. Ratio of the charge storage capacity of the C electrode (14,160 mC/cm2): platinum electrode (12 mC/cm2) is ~1,180.

Desired Partnerships:

  • License
  • Sponsored Research
  • Co-Development
Patent Information: