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Search Results - drug+delivery+and+nanomedicine
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New Device Material for a Flexible Chronic Implantable Neural Interface
Advantages: Superior biocompatibility reduces immune responses. Excellent electrical conductivity enhances signal transmission. Exceptional mechanical strength enables durable and flexible probes. Summary: Implantable neural interfaces (INIs) are devices configured to connect with the human nervous system through electrical means. Such...
Published: 9/3/2024
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Inventor(s):
Stephen Saddow
,
Chenyin Feng
,
Christopher Frewin
Keywords(s):
Drug Delivery and Nanomedicine
,
Medical Therapeutics Cell Therapy
,
Nanotechnology
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Medical > Biomedical Engineering
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Technology Classifications > Medical > Biomaterials
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Technology Classifications > Medical > Medical Devices
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Technology Classifications > Medical > Neuroscience
Regulated Delivery of Antibiotic and Antifungal Drugs Via Controlled Degradable Chondroitin Sulfate Particles
Advantages: Novel synthesis of Chondroitin sulfate (CS) particles for encapsulation of antibiotic and antifungal drugs. Synthesis can be fine-tuned to produced non-degradable, slightly degradable, and completely degradable CS drug carriers, for a variety of therapeutic applications. CS particles were successfully tested for encapsulation...
Published: 5/14/2024
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Inventor(s):
NURETTIN SAHINER
,
Ramesh Ayyala
Keywords(s):
Drug Delivery and Nanomedicine
,
Pharmaceuticals
Category(s):
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical
Targeting Cellular Senescence by PD-L1 Binding Peptide Engineered Extracellular Vesicles
Advantages: Engineered extracellular vesicles (EVs) by surface modification with PD-L1 binding peptide and PEGylation to target senescent VSMCs. Promising novel interventions for age-related and vascular diseases. Efficacy: Proven uptake of modified EVs in the aorta of old mice and senescent VSMCs. Summary: Targeting senescent cells, particularly...
Published: 8/22/2024
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Inventor(s):
Wanling Xuan
,
Srinivas Tipparaju
,
Vijaykumar Sutariya
Keywords(s):
Drug Delivery and Nanomedicine
,
Genetics
,
Peptides
Category(s):
Technology Classifications > Medical > Medical Nanotechnology
,
Technology Classifications > Medical > Biotechnology
Self-Replicating Cell-Selective Therapy for Atherosclerotic Cardiovascular Disease
Advantages: It utilizes a targeted approach by selectively expressing the therapeutic agent in vascular smooth muscle cells and infiltrating immune cells, it minimizes potential off-target effects and preserves the function of the endothelial cells. By combining two complementary mechanisms, the miRNA switch and siRNA technology, this research...
Published: 6/11/2024
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Inventor(s):
Isabella Hetherington
Keywords(s):
Cardiovascular Diseases
,
Drug Delivery and Nanomedicine
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Pharmaceuticals
A Platform for Selective Intracellular Delivery by the Growth Factor Mediated Macropinocytosis Pathway
Competitive Advantages Targeted drug delivery to tumors Reduced side effects of cancer drugs Made of non-toxic, biodegradable protein Easily synthesized Summary Our inventors have created a novel, cargo carrying nanoparticle for the targeted delivery of drugs to cancer cells. The nanoparticle carries a drug to cancer cells, where the drug...
Published: 8/8/2024
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Inventor(s):
Piyush Koria
,
Raul Iglesias
Keywords(s):
Cancer Treatment
,
Drug Delivery and Nanomedicine
Category(s):
Technology Classifications > Cancer
Hybrid Electro-Plasmonic Modulation of Neural Activity with Visible-Light-Sensitive Gold Nanotransducer Interface
Competitive Advantages Better spatial resolution than standard electrical stimulation Capable of reducing electrical stimulation current input by 40% Specific point stimulation, reducing spread to surrounding tissue 3-fold higher success rate of nerve cell response compared to pure optical stimulation 5-fold better post-stimulation recovery/survival...
Published: 1/18/2024
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Inventor(s):
Ratka Damnjanovic
,
Parveen Bazard
,
Robert Frisina
,
Venkat Bhethanabotla
Keywords(s):
Drug Delivery and Nanomedicine
,
Nanotechnology
,
Neuroscience
Category(s):
Technology Classifications > Electronics
,
Technology Classifications > Electronics > Nanotechnology