Search Results - liqiang+zhang

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Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium
Produces cyclic peptide libraries quickly, cheaply, and without the need of purification. Background: Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 6/21/2024   |   Inventor(s): Qiang Zhang, Huan Chen
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Recovering Critical Elements from Acid Mine Drainage
THE CHALLENGE The demand for certain elements, such as Manganese (Mn), Cobalt (Co), and Nickel (Ni), has surged in recent years due to the rapid growth of battery production for electric vehicles and utility-scale energy storage. The United States government has deemed Co, Ni, and Mn critical elements, primarily because of the country’s high...
Published: 6/26/2024   |   Inventor(s): Wencai Zhang, Qi Li, Rick Honaker
Keywords(s):  
Category(s): Technology Classifications > Energy, Technology Classifications > Mining and Recycling, Technology Classifications, Technology Classifications > Chemicals/Materials
A Novel Carbohydrate Antibody to GalNac1-3Gal and Its Application for Cancer Diagnostic and Prognosis
Abstract: Cervical cancer is one of the most common cancers among women worldwide. Currently, physical descriptors such as tumor size and depth are the primary factors used for deciding the course of treatment. Despite significant efforts to identify prognostic biochemical markers or therapeutic targets to improve diagnosis and treatment, none have...
Published: 4/8/2024   |   Inventor(s): Jeffrey Gildersleeve, Zhitao Li, Qian Li, Miriam Anver, Donna Butcher
Keywords(s): ANTIBODY, CERVICAL, GaLNAc1-3Gal, Gildersleeve, Immunohistochemical staining, Larynx, Prognostic marker, SKIN, Squamous Cell
Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology
Serpin-based Polypeptide Compositions for Wound Healing
Wound healing, although complex, is a remarkably organized process involving hemostasis, inflammation, new tissue generation and remodeling. However, when wounds cover a large surface area, become infected, or occur in patients with impaired healing capacity, such as diabetics or the elderly, wound healing can be prolonged and result in chronic ulceration...
Published: 4/14/2023   |   Inventor(s): Alexandra Lucas, Liqiang Zhang, Jordan Yaron, Douglas McFadden
Keywords(s):  
Category(s): Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals
COMBINATION THERAPIES FOR COVID-19 (SARS-COV-2)
The coronavirus disease 2019 (COVID-19) is caused by a novel RNA enveloped coronavirus, SARS-CoV-2 when the virus enters human airway cells via an ACE2-mediated entry process. This entry pathway is facilitated by the cell surface heparan sulfate proteoglycan (HSPG), which enhances viral attachment to the cell surface. Researchers at NIDDK and NCATS...
Published: 7/25/2024   |   Inventor(s): Qi Zhang, Wei Zheng, Catherine Chen, Yihong Ye
Keywords(s): COVID-19, DB4BXX, ENTRY, HEPARAN, option, Sulfate-dependent, Targeting, therapeutic, viral
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Therapeutics
A method to label heparan sulfate proteoglycan in the plasma membrane of mammalian cells
Heparan sulfate proteoglycan (HSPG) is a group of lipid-anchored proteoglycans, engaged in a variety of key biological functions on cell surface. HSPG-mediated endocytosis of neurotoxic protein aggregates has been linked to aging related neurodegenerative diseases. Labeling HSPG is a promising technique to trace cell profile in cell research, monitor...
Published: 7/25/2024   |   Inventor(s): Qi Zhang, Yihong Ye
Keywords(s): Cells, HEPARAN, Label, MAMMALIAN, MEMBRANE, Method, PLASMA, PROTEOGLYCAN, R1XXXX, SULFATE, XCXXXX
Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials
Glucose, pH, and Oxygen Triple Sensor
Glucose, oxygen, and extracellular pH are important components of human metabolic processes -- many diseases are associated with glucose transport and metabolic disorders including diabetes and cancer. Monitoring glucose and cell metabolism can provide invaluable information for understanding these diseases. There are many assays and sensors for glucose,...
Published: 2/23/2023   |   Inventor(s): Yanqing Tian, Liqiang Zhang, Fengyu Su, Deirdre Meldrum, Sean Buizer, Clifford Anderson, Laimonas Kelbauskas, Kristen Lee
Keywords(s): Agriculture and Animal Science, Bio-Technology, Materials and Electronics, Medical Devices and Imaging
Category(s): Advanced Materials/Nanotechnology, Chemical/Biological Sensors, Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Medical Diagnostics/Sensors
Tri-Color DualGlucose and Oxygen Sensors
Glucose and oxygen are important components of human metabolic processes -- many diseases are associated with glucose transport and metabolic disorders including diabetes and cancer. Monitoring glucose and cell metabolism can provide invaluable information for understanding these diseases. There are many assays and sensors for both glucose and oxygen,...
Published: 2/23/2023   |   Inventor(s): Yanqing Tian, Liqiang Zhang, Fengyu Su, Deirdre Meldrum, Sean Buizer
Keywords(s): Agriculture and Animal Science, Bioanalysis, Bio-Technology, Fluorescence, Materials, Medical Devices and Imaging, Sensors
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Life Science (All LS Techs), Medical Diagnostics/Sensors
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023   |   Inventor(s): Leilei Peng, Yu Li, Han Zhang
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Control the epigenetic pathway to increase seed size and potential yield in plants or crops
Maximizing the Yield of Plants and CropsControlling the epigenetic pathway to increase crop yieldshttps://sites.google.com/slu.edu/intellectualproperty/2022/22-008
Published: 8/18/2023   |   Inventor(s): Wenyan Xiao, Arthur Bartels, Qiang Han
Keywords(s):  
Category(s): Industrial Applications
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