Search Results - zhiyuan+mao

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ARPLA: a revolutionary glycoRNA imaging tool with precision and power
Background/problem Glycosylated RNAs (GlycoRNAs) are a newly discovered class of molecules involved in glycosylation. They have been found on the surfaces of various cell types, organisms, and species, further advancing the role of RNA in biological processes. Despite this, our knowledge of glycoRNAs and their functions remains limited, primarily...
Published: 7/26/2024   |   Inventor(s): Yi Lu, Yuan Ma, Weijie Guo, Quanbing Mou
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform
Affinity and Functional Based Screening of T Cell Receptor Repertoire Using Nanovials (Case No. 2024-042)
Summary: Researchers in the Department of Bioengineering at UCLA have developed a hydrogel platform that measures single T cell secretions, aiding in the definition of T cell receptor repertoires for functional immunotherapy applications. Background: T cell immunotherapies, namely T cell receptor (TCR) therapies, have emerged as promising candidates...
Published: 9/20/2024   |   Inventor(s): Dino Di Carlo, Owen Witte, Doyeon Koo, Zhiyuan Mao
Keywords(s): Cancer Immunotherapy, CAR-T cell therapy, Flow Cytometry, hydrogel, Immunooncology, Immunotherapy, Peptide, single cell analysis, T Cell, T cell based therapy
Category(s): Diagnostic Markers > Immunology, Life Science Research Tools > Screening Libraries, Therapeutics > Immunology And Immunotherapy
Targeting Prostate Cancer with a Novel T-Cell Receptor and Tissue-Specific Cancer Antigens for Improved Immune Response (UCLA Case No. 2022-070)
Researchers from UCLA’s Department of Microbiology, Immunology, & Molecular Genetics (MIMG), and the department of Molecular and Medical Pharmacology have identified a set of tissue-specific antigens which have been used to isolate and characterize a group of novel T-cell receptors (TCRs) which target prostate cancer specifically. Furthermore,...
Published: 2/26/2024   |   Inventor(s): Owen Witte, Zhiyuan Mao, Jami Witte, Pavlo Nesterenko, John Lee
Keywords(s): Cancer, cancer antigen, Peptide, peptides, prostate cancer, protein, t-cells
Category(s): Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Grid Control for Unknown Resonance Events (CURE)
Unmet Need: Detection and damping of resonance events in a power grid Complex electric distribution systems cannot be perfectly modeled to reflect every duty cycle and configuration of each component which might come on-line. Recent instances of forced oscillations in wide area networks illustrate the difficulty in quickly locating their causes, and...
Published: 6/9/2023   |   Inventor(s): Vaithianath Venkatasubramanian, Yuan Zhi, Habib Wajid
Keywords(s): Controls, Oscillations, Power grid, Resonance
Category(s): Technologies > Energy & Environment > Energy, Technologies > Energy & Environment > Electrical/Electronics
Fast Implementation Of Equally-Sloped Tomography
SummaryDr. Miao and colleagues at UCLA have developed a novel algorithm that quickly processes high quality image reconstruction of data acquired through Equally-Sloped Tomography.BackgroundTomography is an imaging technique that uses cross-sectional images to depict an object. The utility of this technique ranges across medical imaging of the body...
Published: 7/19/2023   |   Inventor(s): Jianwei Miao, Benjamin Pooya Fahimian, Yu Mao
Keywords(s): Image Processing, Life Science Research Tools, Software, Software & Algorithms
Category(s): Software & Algorithms, Life Science Research Tools, Software & Algorithms > Image Processing, Software & Algorithms > Programs
A System For Visual Presentation Of Concepts From Ontology And Text Documents
PAGE TITLEOverviewPAGE SUMMARYA system lets a user click on a location of a brain model to explore neuroscience ontology terms related to the location. The user can further explore the related terms and related documents through a visualization interface and learn new concept or document relationships derived from the ontology and annotated document...
Published: 7/24/2024   |   Inventor(s): Yuan An, Xia Lin, Mi Zhang, Yue Shang
Keywords(s):  
Category(s): Computing, Software, Analytics & Information Technology, Computing, Software, Analytics & Information Technology > Computing: Algorithms, Computing, Software, Analytics & Information Technology > Computing: Contextual Analytics, Computing, Software, Analytics & Information Technology > Computing: Data Mining, Computing, Software, Analytics & Information Technology > Computing: Databases
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 4/19/2023   |   Inventor(s): Jianming Liang, Yu An, Wei Liu
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging