Search Results - affinity+reagent

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­A TUNABLE PROXIMITY ASSAY THAT CAN OVERCOME DILUTIONAL NON-LINEARITY
­A TUNABLE PROXIMITY ASSAY THAT CAN OVERCOME DILUTIONAL NON-LINEARITY Researchers at Stanford have developed a tunable proximity assay with a wide dynamic range that can detect multiple analytes in a single sample. Blood-based quantification of protein biomarkers is a standard tool for the prediction, diagnosis, and monitoring of disease. Physiological...
Published: 3/17/2023   |   Inventor(s): Hyongsok Soh
Keywords(s): Affinity Reagent, Antibody, Aptamer, Biomolecules, Biosensor System, Blood, Serum
Category(s): Technology Classifications > Biology
­QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES
­QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES Researchers at Stanford have developed a method enabling quantification of intracellular protein levels using oligonucleotide-barcoded antibodies. Multiplexing single cell technologies affords researchers the ability to characterize cell states and identify gene regulatory programs...
Published: 3/17/2023   |   Inventor(s): William Greenleaf, Amy Chen
Keywords(s): Affinity Reagent, Antibody, Biomolecules, Integrated Screening System, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
CONTINUOUS REAL-TIME MONITORING OF BIOMOLECULES IN LIVE SUBJECTS
­CONTINUOUS REAL-TIME MONITORING OF BIOMOLECULES IN LIVE SUBJECTS Researchers at Stanford have developed methods for the continuous real-time monitoring of biomolecules in live subjects. Real-time biosensors that can continuously measure circulating biomolecules in vivo would revolutionize the healthcare system by enabling truly personalized...
Published: 3/17/2023   |   Inventor(s): Hyongsok Soh, Mahla Poudineh, Jing Pan
Keywords(s): Affinity Reagent, Antibody, Aptamer, Biomolecules, Biosensor System, Blood, Microfluidics
Category(s): Technology Classifications > Engineering
ENGINEERED ACE2 RECEPTOR TRAPS TO BLOCK SARS-COV-2 INFECTION
ENGINEERED ACE2 RECEPTOR TRAPS TO BLOCK SARS-COV-2 INFECTION Researchers at UCSF and the Chan Zuckerberg Biohub have developed a set of ACE2 variants which potently block SAR-CoV-2 infection in cells. SARS-CoV-2 is the stain of coronavirus that causes COVID-19. This virus is characterized by spike proteins on its surface, which mediate infection...
Published: 3/17/2023   |   Inventor(s): James Wells, Tanja Kortemme, Jeff Glasgow, Anum Glasgow, Irene Lui, Xin Zhou
Keywords(s): Affinity Reagent, Biomolecules, Therapeutic, Yeast Particle Display
Category(s): Technology Classifications > Biology
DETECTION ASSAY FOR SARS-COV-2 VIRUS
DETECTION ASSAY FOR SARS-COV-2 VIRUS Researchers at UCSF and the Chan Zuckerberg Biohub have developed methods to detect SARS-CoV-2 virus. Clinical laboratory tests and point-of-care tests are needed for screening and diagnosis of individuals infected with SARS-CoV-2 virus. SARS-CoV-2 infection begins with viral Spike protein binding to the human...
Published: 3/17/2023   |   Inventor(s): James Wells, Susanna Elledge, Xin Zhou, Tanja Kortemme, Jeff Glasgow, Anum Glasgow, Irene Lui
Keywords(s): Affinity Reagent, Antibody, Biosensor System, Diagnosis, Fc Domain
Category(s): Technology Classifications > Biology
Generation of Recombinant Affinity Reagents
Creating protein affinity reagents on a proteome-wide scale is one of the greatest challenges of modern medicine. High quality reagents to capture proteins are necessary for elucidating protein function, developing new molecular diagnostics and even therapeutics. Recent advances in protein discovery will necessitate the need for affinity reagents to...
Published: 2/13/2025   |   Inventor(s): Joshua LaBaer, Jie Wang, Ji Qiu, Kevin Gorman, Brian Kay
Keywords(s): Affinity Reagent, Phage display, Protein array
Category(s): Proteomic Assays/Reagents/Tools, Life Science (All LS Techs), Genomic Assays/Reagents/Tools
Conditioned Surfaces for In Situ Molecular Array Synthesis
Array technologies allow scientists to perform large-scale, quantitative, biological analyses such as biomarker discovery, immunomonitoring, epitope mapping and so on. In situ synthesized arrays have advantages in feature density, and sensitivity, however, quality and reliability rely on the quality and consistency of the synthesized molecules. A critical...
Published: 2/13/2025   |   Inventor(s): Neal Woodbury, Zhan-Gong Zhao
Keywords(s): Affinity Reagent, Immunosignature, MicroArray, Peptide Microarray
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools