Search Results - neal+young

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Identification of a Novel Parvovirus for Vaccine Development and Use as a Diagnostic Tool
This technology includes a procedure for novel virus identification in a variety of human specimens by solexa high-throughput sequencing, which allows for the screening a large number of clinical specimens for novel virus discovery in a highly efficient and relatively economical method. By using this technique, we have successfully identified a novel...
Published: 9/5/2024   |   Inventor(s): Ning Zhi, Neal Young, Baoyan Xu, Keji Zhao, Gangqing Hu
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease
Parvovirus B19 Vaccine
Parvovirus B19 (B19V) infection causes fifth disease, a disease characterized by rashes to the face and other parts of the body that primarily affects children. However, adults can also develop fifth disease and it can lead to more severe conditions. Patients that are immunocompromised, such as those who are HIV infected, organ transplant recipients,...
Published: 10/28/2024   |   Inventor(s): Neal Young, Sachiko Kajigaya, Takashi Shimada, Ning Zhi
Keywords(s): Admin Lic Spec Review Mar-09 Active Determina, AgainstB19V, B19, B19V, BBXXXX, CAPSID, Capsids, CODON, CRADA, DA4BXX, DA4XXX, DAXXXX, DC5BXX, DC5XXX, DCXXXX, diagnostic, DNA-based, DXXXXX, GENES, Infection, Non-pennissive, PARTICLE, PARVOVIRUS, Patent Category - Biotechnology, SACGHS DNA Patent Initial Set, UA1XXX, VACCCINE, vaccines, VIRUS-LIKE, VLP-and
Category(s): Collaboration Sought > Collaboration, Application > Vaccines, TherapeuticArea > Infectious Disease, TherapeuticArea > Rare / Neglected Diseases, Application > Diagnostics
Parvovirus B19 Codon Optimized Structural Proteins for Vaccine and Diagnostic Applications
Parvovirus B19 (B19V) is the only known pathogenic human parvovirus. Infection by this viral pathogen can cause transient aplastic crisis in individuals with high red cell turnover, pure red cell aplasia in immunosuppressed patients, and hydrops fetalis during pregnancy. In children, B19V most commonly causes erythema infectiosum, or fifth's disease....
Published: 10/28/2024   |   Inventor(s): Neal Young, Sachiko Kajigaya, Ning Zhi
Keywords(s): Against, AgainstB19V, APPLICATION, B19V, BBXXXX, CAPSID, Cells, CODON, DA4BXX, DA4XXX, DAXXXX, DC5BXX, DC5XXX, DCXXXX, DEVELOPING, DNA-based, DXXXXX, Erythema infectiosum, Fifth Disease, GENES, Human parvovirus B19 infection, Hydrops fetalis, Infection, Non-pennissive, OPTIMIZED, PARTICLE, Parvovirus antenatal infection, Patent Category - Biotechnology, Pure red cell aplasia, USAGE, vaccines, VIRUS-LIKE, VLP-and
Category(s): Collaboration Sought > Collaboration, Application > Vaccines, Application > Diagnostics, TherapeuticArea > Infectious Disease
Erythroid Progenitor Cell Line for Hematological Disease Applications
Plasmodium vivax (malaria) is a significant health concern in many parts of Asia, Latin America, North Africa, and the Middle East. There is a lack of continuous culture systems for this pathogen. The subject technology is an erythroid progenitor continuous cell line (termed CD36E) identified by erythroid markers CD36, CD33, CD44, CD71, CD235, and...
Published: 10/28/2024   |   Inventor(s): Ning Zhi, Neal Young, Susan Wong
Keywords(s): &, Blod, Blood, CD36E, Cell, Cells, continuous, DDXXXX, DISEASES, DXXXXX, Erythroid, Involving, Line, Malaria, Malaria (Plasmodium sp.), Patent Category - Biotechnology, PLASMODIUM, Potential, PRECURSORS, Progenitor, RED, Spp., STUDIES, termed, USES
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials, TherapeuticArea > Infectious Disease
Detection of Mutational Frequency in Human Bone Marrow
To date there have been no adequate methods to determine the frequency of mutations in humans. This invention discloses a method of measuring the mutational frequency of a mitochondrial DNA sequence by sequencing mitochondrial DNA from clonally expanded single cells such as CD34+ human stem cells. Sequencing for mitochondrial DNA polymorphisms and...
Published: 10/28/2024   |   Inventor(s): Neal Young
Keywords(s): CAXXXX, CXXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics
Parvovirus B19 Receptor And Parvovirus B19 Detection
The claimed invention provides a method of detecting the presence of a parvovirus in a sample. Parvoviruses infect animals and man. In man, the only known pathogenic member of this family is parvovirus B19. The inventors have identified the parvovirus B19 receptor which provides for a method to diagnose, prevent, and treat parvovirus infection utilizing...
Published: 4/8/2024   |   Inventor(s): Neal Young
Keywords(s): DA4BXX, DAXXXX, DB4BXX, DBXXXX, DXXXXX
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Diagnostics