Search Results - gennady+margolin

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Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Ultrafast Thin-Film Vapor Deposition Technique

Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...

Published: 11/18/2025 | Inventor(s): Feng Yan, Lin Li

Keywords(s):

Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical

Coherent Generation Of High-Dimensional Structured Light Using A Hyperdimensional Spin-Orbit Microlaser

The current invention describes next-generation high-capacity noise-resilient communication and computing technology. The invention describes a method to coherently generate high-dimensional structured light, including spin-orbit states, in an integrated and scalable way. Problem: On-chip information technologies are mostly limited to two-level systems...

Published: 1/13/2026 | Inventor(s): Liang Feng, Zhifeng Zhang, Haoqi Zhao, Li Ge

Keywords(s): Augmented Reality (AR) & Virtual Reality (VR), Microlasers, Optics & Photonics

Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Materials, Technology Classifications > Imaging

DNA Methylation Based Non-invasive Blood Diagnostic Assay for Precision Cancer Detection and Classification

This technology includes a panel of 46 genomic loci of DNA methylation (represented by CpG dinucleotides on different chromosomes) with application in blood-based cancer screening. The markers robustly distinguish tumor from normal samples using 8 loci and classify 13 different tumor types. Using 39 loci, inventors were able to discriminate between...

Published: 8/13/2025 | Inventor(s): Gennady Margolin, Laura Elnitski

Keywords(s): assay, Based, Blood, CANCER, CLASSIFICATION, Detection, diagnostic, DNA, Humans, Methylation, NON-INVASIVE, PRECISION, VCXXXX, WBXXXX, WIXXXX, XEXXXX

Category(s): Application > Research Materials, Application > Diagnostics, TherapeuticArea > Oncology, Application > Therapeutics

Non-invasive Pan-Cancer Detection Method

One of four deaths in the United States is due to cancer despite an emphasis on prevention, early detection, and treatment that has lowered cancer death rates by 20% in the past two decades. Further improvements in survival rates are likely to come from improving the limits of detection sensitivity at earlier stages of cancer. New approaches that rely...

Published: 8/13/2025 | Inventor(s): Gennady Margolin, Hanna Petrykowska, Laura Elnitski

Keywords(s): CAXXXX, Detection, Listed LPM Campbell as of 4/17/2015, Methods, Pan-Cancer, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, VCXXXX, WBXXXX, XBXXXX, XCXXXX, XEXXXX, YAXXXX, YBXXXX, YGXXXX

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, Application > Diagnostics, Application > Research Materials, ResearchProducts > Computational models/software, TherapeuticArea > Oncology, Application > Software / Apps

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 1/9/2026 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

Twistron Mechanical Energy Harvesters

Mechanical energy harvesters are needed for diverse applications, including self-powered wireless sensors, structural and human health monitoring systems, automotive technologies, and the extraction of energy from ocean waves. Until now, few harvesters have been flexible enough to be used as yarns in textiles, and the performance of such yarns has been...

Published: 6/26/2024 | Inventor(s): Shi Hyeong Kim, Carter Haines, Na Li, Keon Jung Kim, Tae Jin Mun, Changsoon Choi, Jiangtao Di, Shaoli Fang, Seon Jeong Kim, Ray Baughman

Keywords(s): Automotive, Carbon Nanomaterials, Carbon Nanotubes, Electronics, Energy, Cleantech & Environmental, Engineering & Physical Sciences, Renewable Energy, Sensors & Controls, Textiles, Wireless

Category(s): Nanotechnology

Intelligent Textiles Prepared from Nanofiber Yarns and Polymer Fiber Actuators

While there has always been a desire for smart textiles, including fabrics which adapt depending on environmental stimuli, it has yet to be effectively accomplished due to the lack of suitable materials. These polymer fiber actuators have enabled the creation of fabrics that can reversibly change properties such as porosity, shape, color and texture....

Published: 4/22/2021 | Inventor(s): Ray Baughman, Ozer Goktepe, Fatma Goktepe, Na Li, Marcio Lima, Carter Haines, Shaoli Fang

Keywords(s): Engineering & Physical Sciences, Industrial & Manufacturing, Nanotechnology, Polymers, Textiles

Category(s): Materials

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