Search Results - xinyue+liu

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CNN Architecture for Disease Identification from Retinal Images
The rise of artificial intelligence is changing the shape of many different fields, and ophthalmic medicine is no exception. Convolutional neural networks (CNNs) have achieved remarkable results in the assisted diagnosis of ophthalmic diseases. However, they face challenges such as limited labeling and small dataset sizes. In recent years, self-supervised...
Published: 3/19/2025   |   Inventor(s): Yalin Wang, Xin Li, Wenhui Zhu, Oana Dumitrascu
Keywords(s): Medical Devices and Imaging, Medical Software
Category(s): Artificial Intelligence/Machine Learning, Computing & Information Technology, Imaging, Life Science (All LS Techs), Medical Imaging
Light Scattering Fiber with Enhanced Side Emission for Photobioreactors
Executive Summary Photobioreactors are used to cultivate various photosynthetic microorganisms to produce useful materials such as biofuels, value added chemicals. These systems regulate key factors including light, temperature, carbon dioxide concentration, and nutrients. A key challenge with photobioreactors is getting enough light into the medium...
Published: 4/3/2025   |   Inventor(s): Xinyue Liu, Yijie Cheng
Keywords(s):  
Category(s): Environmental, Chemicals, Biotechnology, Photonics
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 2/13/2025   |   Inventor(s): Li Liu, Jingmin Shu
Keywords(s):  
Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices
Accelerating Multiview Registration and Iterative Deconvolution to Improve Spatial Resolution and Contrast in Fluorescence Microscopy
This technology includes algorithms and software that improve the speed of iterative deconvolution, a common method for improving spatial resolution and contrast in fluorescence microscopy images. These algorithms also improve the registration of multiview datasets, and apply deep learning to accelerate spatially varying deconvolution.
Published: 8/12/2024   |   Inventor(s): Hari Shroff, Yue Li, Yicong Wu, Patrick La Riviere, Min Guo, Huafeng Liu
Keywords(s):  
Category(s): Application > Research Materials, Application > Software / Apps, ResearchProducts > Research Equipment
Human Brain Proteins with Evidence Consistent with Causality of Alzheimer’s and Depression
Application Research and therapeutic targets for Alzheimer’s disease, depression, and other neurological conditions mediated by protein expression in the brain. Key Benefits These findings can be utilized as a research tool to better understand the genetic basis of Alzheimer’s disease. Can also be utilized to develop therapeutics for...
Published: 2/13/2025   |   Inventor(s): Aliza Wingo, Thomas Wingo, Yue Liu, Allan Levey, Nicholas (Nick) Seyfried, Duc Duong
Keywords(s): Drug Target Identification
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Therapeutics
Novel Anti-HIV Compounds Using Peptides or Peptide Mimetics
Abstract: The subject invention describes a new class of compounds (such as peptides or mimetics) that target viral RNAs and inhibit the viral life cycle by blocking the viral recognition process. More specifically, these compounds are the first against an RNA Target - currently there are no clinical drugs against RNA targets in the treatment of any...
Published: 4/8/2024   |   Inventor(s): Yun-Xing Wang, Liu Yu, Ping Yu, Ina O'Carroll
Keywords(s): Anti-Viral, HIV
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Infectious Disease
Method and Device for Selectively Labeling RNA
Abstract: Current methods of labeling and synthesizing RNA do not allow for multiple labels or long RNA segments to be synthesized for large RNA on a milligram scale. Investigators at the NCI Structure Biophysics Lab and UT Health Science Center have developed a method to selectively label RNA at specific residues and/or segments using a hybrid solid-liquid...
Published: 12/10/2024   |   Inventor(s): Yun-Xing Wang, Liu Yu, Rui Sousa
Keywords(s): crystallography, Fluorophore labeling, FRET, Isotope labeling, Labeling sensor, NMR Spectroscopy
Category(s): Application > Diagnostics, Collaboration Sought > Licensing, TherapeuticArea > Oncology
Metabolic activity diffusion imaging (MADI): dye-free, high-resolution MRI metabolic imaging
Summary The current technology is a contrast agent-free method of metabolic imaging based on detection of Na/K ATPase activity with MRI, that provides significantly higher resolution than current approaches such as PET. Technology Overview Measuring metabolic activity in vivo can facilitate diagnoses of disease states and therapeutic responses....
Published: 1/15/2024   |   Inventor(s): Gregory Wilson, Jeffrey Maki, Charles Springer, Jr., Xin Li, William (Bill) Rooney, Brendan Moloney, Wei Huang, Tom Barbara, Eric Baker
Keywords(s): Diagnostics, Imaging, Imaging - MRI, Software, Software - Other
Category(s): Imaging, Software
A Gamma-ray Photon Counting Detector Based on Side-readout of Monolithic Scintillator Layers
Researchers at the University of Arizona have developed a gamma-ray photon counting device that works similarly to PET, but with a novel architecture that improves the accuracy and speed in determining the location of the biological targets, and is less costly to manufacture. Background: Positron Emission Tomography (PET) is a common and reliable...
Published: 11/22/2023   |   Inventor(s): Lars Furenlid, Xin Li
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Sensors and Detection
Real-Time RT-PCR Assay for the Rapid Detection of Rabies and Other Lyssaviruses
Rabies occurs in more than 150 countries and territories, resulting in at least 55,000 human deaths per year worldwide according to World Health Organization estimates. Rabies is a vaccine-preventable viral disease caused by numerous lyssaviruses that are found in a variety of animal species throughout the world. Rabies virus infects the central nervous...
Published: 10/28/2024   |   Inventor(s): Yu Li
Keywords(s): assay, DA4XXX, DDXXXX, Diagnostics, LYSSAVIRUSES, Modified, NCEZID, NCEZID-DHCPP, Non-rabies, Probe, rabies, REAL-TIME, RT-PCR, VLXXXX, VOXXXX, WBXXXX, WGXXXX, WHXXXX, WIXXXX, XEXXXX, YBXXXX, YGXXXX
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Therapeutics, Application > Research Materials, Application > Diagnostics
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