Search Results - crystallography

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Method and Device for Selectively Labeling RNA
Abstract: Current methods of labeling and synthesizing RNA do not allow for multiple labels or long RNA segments to be synthesized for large RNA on a milligram scale. Investigators at the NCI Structure Biophysics Lab and UT Health Science Center have developed a method to selectively label RNA at specific residues and/or segments using a hybrid solid-liquid...
Published: 4/8/2024   |   Inventor(s): Yun-Xing Wang, Liu Yu, Rui Sousa
Keywords(s): crystallography, Fluorophore labeling, FRET, Isotope labeling, Labeling sensor, NMR Spectroscopy
Category(s): Application > Diagnostics, Collaboration Sought > Licensing, TherapeuticArea > Oncology
Microfluidic Crystallization Array based on Gradient Mixing
Standard diffusion-based crystallization methods are slow and difficult to quantitate, making them extremely ineffective. Initial materials for crystallization are prohibitively expensive, limiting applications such as serial femtosecond crystallography. Researchers around the world have been working on different micro-/nanobatch techniques to simplify...
Published: 2/23/2023   |   Inventor(s): Alexandra Ros, Bahige Abdallah
Keywords(s): Bio-Technology, Crystallography, Drug Screening, Therapeutics
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors, Pharmaceuticals, Physical Science, Proteomic Assays/Reagents/Tools