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Search Results - yun-xing+wang
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Novel Anti-HIV Compounds Using Peptides or Peptide Mimetics
Abstract: The subject invention describes a new class of compounds (such as peptides or mimetics) that target viral RNAs and inhibit the viral life cycle by blocking the viral recognition process. More specifically, these compounds are the first against an RNA Target - currently there are no clinical drugs against RNA targets in the treatment of any...
Published: 4/8/2024
|
Inventor(s):
Yun-Xing Wang
,
Liu Yu
,
Ping Yu
,
Ina O'Carroll
Keywords(s):
Anti-Viral
,
HIV
Category(s):
Collaboration Sought > Licensing
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
Method and Device for Selectively Labeling RNA
Abstract: Current methods of labeling and synthesizing RNA do not allow for multiple labels or long RNA segments to be synthesized for large RNA on a milligram scale. Investigators at the NCI Structure Biophysics Lab and UT Health Science Center have developed a method to selectively label RNA at specific residues and/or segments using a hybrid solid-liquid...
Published: 12/10/2024
|
Inventor(s):
Yun-Xing Wang
,
Liu Yu
,
Rui Sousa
Keywords(s):
crystallography
,
Fluorophore labeling
,
FRET
,
Isotope labeling
,
Labeling sensor
,
NMR Spectroscopy
Category(s):
Application > Diagnostics
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
Natural Compound for Bitter Taste Masking
Reduces the Bitter Taste of Nutraceuticals and Medications, Improving Their Palatability This naturally occurring anti-bittering compound reduces the bitter taste of certain foods and pharmaceuticals, improving their palatability and consumption. Bitterness is one of the five basic taste modalities. People have strong aversions to bitterness, particularly...
Published: 2/20/2024
|
Inventor(s):
Yu Wang
,
Jinpyo An
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Nutraceutical
,
Technology Classifications > Others > Others
Real-Time PCR Assay for Specific Detection of Haemophilus influenzae Serotypes A and B
Haemophilus influenzae is responsible for life-threatening respiratory infections including meningitis. This assay allows for the qualitative detection of the bacterial meningitis pathogen H. influenzae serotype A (Hia) and serotype B (Hib) in fluid samples, without detecting any of the other serotypes of H. influenzae. This invention is capable of...
Published: 10/28/2024
|
Inventor(s):
Xin Wang
,
Cynthia Hatcher
,
Raydel Anderson
,
Mary Theodore
,
Leonard Mayer
,
Jennifer Thomas
Keywords(s):
CDC Docket Import
,
CDC Docket Import CDC Prosecuting
,
DA3XXX
,
DAXXXX
,
Detection
,
DXXXXX
,
HAEMOPHILUS
,
INFLUENZAE
,
OID-NCIRD-DBD
,
SELECTIVE
Category(s):
Collaboration Sought > Licensing
,
TherapeuticArea > Infectious Disease
,
Application > Diagnostics
Novel Zinc Metallochaperone (ZMC) Complexes for Treatment of p53-Mutated Cancers
A) Novel mechanism of action: a short exposure to ZMCs increases zinc levels in tumors enough to restore normal structure/function to mutant p53 which leads to p53 mediated cancer cell death. B) Novel formulation: Synthesizing ZMCs as a zinc-loaded complex (Zn-1) improves survival in a pancreatic cancer mouse model compared to the ZMC compound alone....
Published: 12/4/2024
|
Inventor(s):
Darren Carpizo
,
David Augeri
,
Spencer Kimball
,
Xin Yu
Keywords(s):
Anti-cancer
,
Small molecules
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Therapeutics
Silk Wrinkles: Tuning Structural Protein Coformation for Dynamic, Responsive, Multifunctional Micropatterns
PROBLEM Protein micropatterning and nanopatterning have long provided sophisticated strategies for a wide range of applications including biointerfaces, tissue engineering, optics/photonics, and bioelectronics. In recent years, various micro- and nanofabrication technologies have been utilized to transform a water-based suspension of silk protein into...
Published: 9/30/2020
|
Inventor(s):
Fiorenzo Omenetto
,
Yu Wang
Keywords(s):
Category(s):
Biomaterials
Disturbed Self-assembly: Growing Block Copolymer Nanosheet (BCNS) Densely and Naturally
AbstractNanosheet plays an important role in the development of clinical therapeutics and diagnostics e.g., bioimaging/sensing, drug delivery systems and tissue engineering. As one of the most important approaches to preparing nanomaterials, self-assembly is able to give rise to various nanostructures from zero-dimension nanoparticles to three-dimension...
Published: 10/8/2024
|
Inventor(s):
Yu Wang
,
Weihong Zhong
Keywords(s):
Category(s):
Technologies > Next Generation Materials & Technology > Nanotechnology
Functionalized Porous Polymer Nanocomposites via Introducing Functional Components into Emulsion Systems
AbstractFunctional porous polymer films are of great interest to academia as well as industry for a variety of applications, such as gas separation, water purification and sensors. A porous structure can not only reduce the density of the material, but can also remarkably increase the surface/interface area, which can be used for various functionalizations....
Published: 10/8/2024
|
Inventor(s):
Yu Wang
,
Weihong Zhong
,
Bin Li
Keywords(s):
Category(s):
Technologies > Energy & Environment > Clean Tech
Adhesive Conductive Binder for Battery Electrodes
Abstract Researchers at WSU have developed a high-performance hybrid conductive adhesives (HCA), which showed strong adhesion properties, high ionic and electric conductivities and good elasticity.Energy storage devices are in desperate need of high-performance binder materials that can maintain good/stable contact among all the components and at the...
Published: 10/8/2024
|
Inventor(s):
Yu Wang
,
Weihong Zhong
Keywords(s):
Category(s):
Technologies > Energy & Environment > Clean Tech
,
Technologies > Next Generation Materials & Technology > Advanced Materials
,
Technologies > Energy & Environment > Electrical/Electronics
,
Technologies > Energy & Environment > Energy
Protein-based Nanofabrics as Multi-functional “Green” Air Filtering Materials for High Efficiency Particulate and Toxic Chemical Filtration
AbstractAir filters currently in the market cannot simultaneously purify the air from particles and chemicals effectively. The non-degradable synthetic nature of existing products also creates environmental issues. To solve these problems, researchers at Washington State University have developed a green multi-functional air filter. This filter is...
Published: 10/8/2024
|
Inventor(s):
Weihong Zhong
,
Hamid Souzandeh
,
Yu Wang
Keywords(s):
Category(s):
Technologies > Energy & Environment > Clean Tech
,
Technologies > Health & Well-being > Chemistry
,
Technologies > Health & Well-being > Global Human and Animal Health
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