Search Results - scarring

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Self-delivery USP10 siRNA to promote regenerative healing-new IP
This technology employs an engineered self-delivering siRNA to selectively reduce USP10 protein levels in tissues, thereby promoting regenerative healing and suppressing pathological scarring. Preclinical studies in the eye demonstrate a favorable safety profile and robust efficacy, supporting the potential of this approach for treating fibrotic disease...
Published: 1/29/2026   |   Inventor(s): Audrey Bernstein, Sean McCauley, Alexey Wolfson, Tere Williams
Keywords(s): fibrosis, opthalmology, scarring, siRNA, skin diseases, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Upstate Medical University
Self-Deliverable siRNA to Prevent Corneal Scarring
Targeted gene silencing technology promotes corneal wound healing. Background: Ocular scarring after surgery, trauma, or infection leads to vision loss and blindness. Blindness due to corneal scarring can currently only be resolved by transplantation, necessitating new approaches in regenerative wound healing in the eye. Technology Overview:...
Published: 8/26/2025   |   Inventor(s): Audrey Bernstein
Keywords(s): cornea, fibrosis, integrin, myofibroblast, scarring, TAF, wound healing
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University