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Search Results - integrin
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Self-Deliverable siRNA to Prevent Corneal Scarring
Targeted gene silencing technology promotes corneal wound healing. Background: Ocular scarring after surgery, trauma, or infection leads to vision loss and blindness. Blindness due to corneal scarring can currently only be resolved by transplantation, necessitating new approaches in regenerative wound healing in the eye. Technology Overview:...
Published: 9/24/2024
|
Inventor(s):
Audrey Bernstein
Keywords(s):
cornea
,
fibrosis
,
integrin
,
myofibroblast
,
scarring
,
wound healing
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Therapeutics and Vaccines
,
Technology Classifications > Healthcare
,
Campus > Upstate Medical University
Monoclonal Antibody Against Human Alpha-5
Integrin
that Does Not Disrupt Adhesive Function
This technology includes a rat monoclonal antibody termed mAb11 was generated against the human alpha-5
integrin
subunit and can provide immunological characterizations without disrupting integrin adhesive function. It permits characterization of its localization even if the receptor is bound to its fibronectin ligand. The antibody is commercially available...
Published: 7/25/2024
|
Inventor(s):
Steven Akiyama
,
Susan Yamada
,
Kenneth Yamada
Keywords(s):
Against
,
Alpha-5
,
ANTIBODY
,
DISRUPT
,
DOES
,
FUNCTION
,
Human
,
INTEGRIN
,
monoclonal
,
That
,
WIXXXX
,
XAXXXX
Category(s):
Application > Research Materials
,
ResearchProducts > Antibodies
,
TherapeuticArea > Immunology