Search Results - techpub+algolia+%3e+therapeutics

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Methioninase Inducing Virus for Anti-Cancer Therapy
Application A set of viral constructs that induce regulatable expression of methionine degrading enzyme for treatment of brain tumors. Key Benefits Built-in Tet-responsive element ensures precise regulation, preventing unwanted enzyme activity. IL-2 signal directs the enzyme for secretion, optimizing its therapeutic impact. Specific delivery...
Published: 12/9/2025   |   Inventor(s): Timothy R. Gershon, Leon McSwain, Andrey Tikunov
Keywords(s): Drug Discovery, Enzyme and Protein Research, Oncology Treatments, Therapeutics
Category(s): TechPub Algolia, TechPub Algolia > Therapeutics
Precision Protein Repair Platform for Missense Mutations
Application This technology enables targeted chemical correction of missense mutations in proteins using a modular heterotrifunctional molecule platform. Key Benefits Restores protein function by chemically mimicking healthy amino acid side chains. Modular toolkit allows rapid customization for diverse protein targets. Validated across multiple...
Published: 11/12/2025   |   Inventor(s): Monika Raj
Keywords(s): Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Protein and Peptide Therapeutics, Research Tools
Category(s): TechPub Algolia > Therapeutics
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 12/5/2025   |   Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla
Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools
Category(s): TechPub Algolia > Therapeutics
Gene Editing for Head and Neck Cancer Treatment
Application Method for delivering gene-editing therapeutic in head and neck cancers. Key Benefits CRISPR/CAS9-based gene editing mechanism targeting novel disease-modifying gene. Liquid nanoparticle encapsulation permitting in vivo delivery. Market Summary Head and neck cancers (HNC) are the 7th most common global cancer, accounting for 3%...
Published: 11/7/2025   |   Inventor(s): Yong Teng, Yamin Li
Keywords(s): Drug Discovery, Drug Target Identification, Gene Therapy and Editing, Nanoparticle Drug Delivery, Oncology Treatments, Reagents, Biomaterials, and Plasmids
Category(s): TechPub Algolia > Therapeutics
Anticancer Agent with N-Glycan Specificity
Application An engineered protein for targeting disease-associated N-glycans. Key Benefits High affinity, pH insensitive, no cofactors required. Applications in anticancer and antiviral therapeutics and research. Can aid in manufacturing monoclonal antibodies with desired N-glycosylation properties. Market Summary Glycosylation involves post-translation...
Published: 12/5/2025   |   Inventor(s): Eric J. Sundberg, Diego Sastre, Maros Huliciak
Keywords(s): Antibodies, Biologics, Biomarkers, Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Microbiology and Infectious Disease Treatments, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics
Treatment for Dengue Virus (DENV) Infection
Application Antiviral therapeutic for multiple Dengue virus serotypes. Key Benefits Targets conserved regions of DENV genomes, enabling efficacy across serotypes. Mitigates lethal infections with a single lipid nanoparticle (LNP) based dose in mice. Minimal off-target effects. Market Summary Despite 390+ million annual DENV infections, there...
Published: 10/30/2025   |   Inventor(s): Philip Santangelo, Daryll Vanover, Chiara Zurla, Lorena Carvalho de Souza Chaves
Keywords(s): DNA and RNA Vaccines, Drug Discovery, Drug Target Identification, Microbiology and Infectious Disease Treatments
Category(s): TechPub Algolia > Therapeutics
Combinatorial Therapy for Preserving Muscle Mass During Weight Loss
Application A combinatorial therapy to preserve muscle mass during semaglutide weight loss treatment. Key Benefits Preserves lean mass during semaglutide treatment in preclinical mouse models. Increases overall fat loss without affecting food/water intake during semaglutide treatment in preclinical mouse models. Market Summary The prevalence...
Published: 12/5/2025   |   Inventor(s): Todd Golde, Yong Ran, Eric Krause, Annette De Kloet, Karen Scott
Keywords(s): Antibodies, Biologics, Drug Discovery, Drug Target Identification, Metabolic Disease Treatments, Musculoskeletal Treatments, Personalized Medicine
Category(s): TechPub Algolia > Therapeutics
Molecules Targeting Inflammatory Signaling
Application A group of small molecules for treating central and peripheral diseases associated with inflammation. Key Benefits Applicable to a wide variety of central nervous system and peripheral diseases. Can bypass side effects of existing therapeutics targeting similar inflammatory pathways. High target selectivity and aqueous solubility. Capability...
Published: 12/5/2025   |   Inventor(s): Raymond (Ray) Dingledine, Radhika Amaradhi, Shabber Mohammed, Thota Ganesh
Keywords(s): Immunology and Inflammation Treatments, Neurology and Pain Treatments, Oncology Treatments, Small Molecule, Women's Health
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Function-Based Elopement Intervention Manual
Application A manualized intervention for the assessment and treatment of elopement for autistic youth. Key Benefits Provides clear step-by-step instructions/guidance for clinicians to coach caregivers. Employs specific strategies to reduce elopement incidents, minimize safety risks, and enforce readiness response. Parents and therapists find...
Published: 10/6/2025   |   Inventor(s): Mindy Scheithauer, Sarah Slocum Freeman, Nathan (Nate) Call, Joanna E. Mevers, Colin Muething, Lawrence Scahill
Keywords(s): Healthcare Professional Education and Training, Patient and Support Education and Training, Pediatrics
Category(s): TechPub Algolia > Therapeutics
MKK3/MYC Protein-Protein Interaction Inhibitor Overcomes Resistant Non-Small Cell Lung Cancer
Application A therapeutic use for SGI-1027 in the treatment of Osimertinib-resistant non-small cell lung cancer (NSCLC). Key Benefits The MKK3/MYC protein-protein interaction inhibitor SGI-1027 effectively decreases MYC levels in Osimertinib-resistant NSCLC cell lines. The combination of SGI-1027 with Osimertinib offers synergistic benefits over...
Published: 12/5/2025   |   Inventor(s): Andrey Ivanov, Haian Fu, Shi-Yong Sun, Zhen Chen
Keywords(s): Drug Discovery, Oncology Treatments, Protein and Peptide Therapeutics
Category(s): TechPub Algolia > Therapeutics
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