Search Results - techpub+algolia+%3e+therapeutics

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Small Molecule Inhibitors of the p38/MK2 Protein Interaction
Application New class of small molecule inhibitors with therapeutic potential for inflammatory diseases through disruption of the p38/MK2 protein-protein interaction. Key Benefits Therapeutic potential and utility for various inflammatory diseases. May have potentially fewer off-target effects and dose-limiting toxicities. May serve as a foundation...
Published: 7/21/2026   |   Updated: 7/9/2026   |   Inventor(s): Andrey Ivanov, Haian Fu
Keywords(s): Immunology and Inflammation Treatments, Neurology and Pain Treatments, Small Molecule, Therapeutics
Category(s): TechPub Algolia > Therapeutics
New Treatment for Pain
Application Veragranine A analogs with improved synthetic efficiency and enhanced potency for the treatment of pain. Key Benefits Increased synthetic efficiency of Veragranine A analogs, helping address supply limitations. Synthetic analogs demonstrate greater potency than Veragranine A and may offer improved pharmacological response. The analogs...
Published: 7/21/2026   |   Updated: 7/9/2026   |   Inventor(s): Mingji Dai, Donghui Ma, Reem Al-Ahmad, Rajesh Khanna
Keywords(s): Immunology and Inflammation Treatments, Neurology and Pain Treatments
Category(s): TechPub Algolia > Therapeutics
Engineering Asymmetrically Glycosylated IgG Antibodies
Application A method to produce asymmetrically glycosylated antibodies for the treatment and prevention of diseases including cancer, auto-immune disorders, and infectious diseases. Key Benefits This strategy has potential to produce a new class of therapeutic antibodies for treating and preventing a wide range of human diseases. Market Summary Monoclonal...
Published: 7/21/2026   |   Updated: 6/15/2026   |   Inventor(s): Tala Azzam, Eric J. Sundberg, Jonathan Du, Diego Sastre
Keywords(s): Antibodies, Platform
Category(s): TechPub Algolia > Therapeutics
MTHFD2-Targeting Peptide Decoy for Chemotherapy-Resistant Cancers
Application An engineered decoy peptide, DMp39, targeting DLAT-MTHFD2 interaction, as a sensitizer for chemotherapy resistant cancer treatment. Key Benefits Restores chemotherapy sensitivity in resistant tumors. Targets the DLAT-MTHFD2 pathway with high specificity and minimal off-target toxicity. Market Summary Chemotherapy resistance remains...
Published: 6/22/2026   |   Updated: 6/15/2026   |   Inventor(s): Sumin Kang, Jung Seok Hwang, Jaehyun Kim
Keywords(s): Oncology Treatments, Protein and Peptide Therapeutics, Therapeutics
Category(s): TechPub Algolia > Therapeutics
MPL Protein Targeting for Cancer Therapy and Transplant Preparation
Application Non-genotoxic hematopoietic stem cell transplantation conditioning regimen. Key Benefits Selective depletion of hematopoietic stem cells creates adequate niche space to allow donor engraftment without significant off target effect. Non-genotoxic conditioning regimen. CAR-T cells can have an anti-MPL positive leukemia effect before...
Published: 7/21/2026   |   Updated: 4/27/2026   |   Inventor(s): Shanmuganathan (Shan) Chandrakasan, H. (Harold) Trent Spencer, Christopher Doering, Lauren Fleischer, Gianna Branella, Jaquelyn Zoine, Harrison Brown
Keywords(s): Antibodies, Cell Therapy, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics
Automated Deep Brain Stimulation Programming
Application A program to optimize parameters for deep brain stimulation. Key Benefits Can provide patient-specific deep brain stimulation parameters. May reduce the frequency of programming clinic visits May improve clinical outcomes by selecting optimal stimulation parameters. Market Summary Deep brain stimulation (DBS) is currently approved...
Published: 3/10/2026   |   Updated: 3/2/2026   |   Inventor(s): Svjetlana Miocinovic, Babak Mahmoudi
Keywords(s): Hospital and Surgical Assistance, Neurology and Pain Treatments
Category(s): TechPub Algolia > Software, TechPub Algolia > Therapeutics
Next Gen Immune-Optimized Gene Delivery
Application An advanced gene therapy approach that improves therapeutic efficiency by protecting transgene expressing cells from host immune responses, through modulation of a key immune checkpoint pathway. Key Benefits Potential for enhanced efficiency across viral and non-viral gene delivery systems, including AAV, lentivirus, LNPs, and electroporation. Enables...
Published: 7/21/2026   |   Updated: 2/23/2026   |   Inventor(s): Matthew (Matt) Gardner, Michael Kuipa, Abubakarr Koroma, Isai Leguizamo
Keywords(s): Biologics, Cell Therapy, Gene Therapy and Editing, Immunology and Inflammation Treatments, Oncology Treatments, Platform, Regenerative Medicine
Category(s): TechPub Algolia > Therapeutics
Targeted Candidalysin Binders for Fungal Infection Control
Application A theranostic scaffold-derived protein that neutralizes candidalysin toxin. Key Benefits Different mechanism of action compared to current antifungal drugs, reducing the risk of resistance. Derived from human protein for lower immune response and produced cost-effectively in simple bacterial media. Small size improves tissue penetration...
Published: 7/21/2026   |   Updated: 1/20/2026   |   Inventor(s): Sohail Khoshnevis, Eric J. Sundberg, Maros Huliciak
Keywords(s): Diagnostics, Drug Discovery, Hydrogels, Protein and Peptide Therapeutics, Therapeutics
Category(s): TechPub Algolia > Therapeutics
Methioninase Inducing Virus for Anti-Cancer Therapy
Application A set of viral constructs that induce regulatable expression of methionine degrading enzyme for treatment of brain tumors. Key Benefits Built-in Tet-responsive element ensures precise regulation, preventing unwanted enzyme activity. IL-2 signal directs the enzyme for secretion, optimizing its therapeutic impact. Specific delivery...
Published: 6/15/2026   |   Updated: 12/9/2025   |   Inventor(s): Leon McSwain, Andrey Tikunov, Timothy R. Gershon
Keywords(s): Drug Discovery, Enzyme and Protein Research, Oncology Treatments, Therapeutics
Category(s): TechPub Algolia, TechPub Algolia > Therapeutics
Precision Protein Repair Platform for Missense Mutations
Application This technology enables targeted chemical correction of missense mutations in proteins using a modular heterotrifunctional molecule platform. Key Benefits Restores protein function by chemically mimicking healthy amino acid side chains. Modular toolkit allows rapid customization for diverse protein targets. Validated across multiple...
Published: 3/30/2026   |   Updated: 11/7/2025   |   Inventor(s): Monika Raj
Keywords(s): Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Protein and Peptide Therapeutics, Research Tools
Category(s): TechPub Algolia > Therapeutics
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