Search Results - techpub+algolia+%3e+therapeutics

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Treatment for Dengue Virus (DENV) Infection
Application Antiviral therapeutic for multiple Dengue virus serotypes. Key Benefits Targets conserved regions of DENV genomes, enabling efficacy across serotypes. Mitigates lethal infections with a single lipid nanoparticle (LNP) based dose in mice. Minimal off-target effects. Market Summary Despite 390+ million annual DENV infections, there...
Published: 10/30/2025   |   Inventor(s): Philip Santangelo, Daryll Vanover, Chiara Zurla, Lorena Carvalho de Souza Chaves
Keywords(s): DNA and RNA Vaccines, Drug Discovery, Drug Target Identification, Microbiology and Infectious Disease Treatments
Category(s): TechPub Algolia > Therapeutics
Combinatorial Therapy for Preserving Muscle Mass During Weight Loss
Application A combinatorial therapy to preserve muscle mass during semaglutide weight loss treatment. Key Benefits Preserves lean mass during semaglutide treatment in preclinical mouse models. Increases overall fat loss without affecting food/water intake during semaglutide treatment in preclinical mouse models. Market Summary The prevalence...
Published: 10/24/2025   |   Inventor(s): Todd Golde, Yong Ran, Eric Krause, Annette De Kloet, Karen Scott
Keywords(s): Antibodies, Biologics, Drug Discovery, Drug Target Identification, Metabolic Disease Treatments, Musculoskeletal Treatments, Personalized Medicine
Category(s): TechPub Algolia > Therapeutics
Molecules Targeting Inflammatory Signaling
Application A group of small molecules for treating central and peripheral diseases associated with inflammation. Key Benefits Applicable to a wide variety of central nervous system and peripheral diseases. Can bypass side effects of existing therapeutics targeting similar inflammatory pathways. High target selectivity and aqueous solubility. Capability...
Published: 10/15/2025   |   Inventor(s): Raymond (Ray) Dingledine, Radhika Amaradhi, Shabber Mohammed, Thota Ganesh
Keywords(s): Immunology and Inflammation Treatments, Neurology and Pain Treatments, Oncology Treatments, Small Molecule, Women's Health
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Function-Based Elopement Intervention Manual
Application A manualized intervention for the assessment and treatment of elopement for autistic youth. Key Benefits Provides clear step-by-step instructions/guidance for clinicians to coach caregivers. Employs specific strategies to reduce elopement incidents, minimize safety risks, and enforce readiness response. Parents and therapists find...
Published: 10/6/2025   |   Inventor(s): Mindy Scheithauer, Sarah Slocum Freeman, Nathan (Nate) Call, Joanna E. Mevers, Colin Muething, Lawrence Scahill
Keywords(s): Healthcare Professional Education and Training, Patient and Support Education and Training, Pediatrics
Category(s): TechPub Algolia > Therapeutics
MKK3/MYC Protein-Protein Interaction Inhibitor Overcomes Resistant Non-Small Cell Lung Cancer
Application A therapeutic use for SGI-1027 in the treatment of Osimertinib-resistant non-small cell lung cancer (NSCLC). Key Benefits The MKK3/MYC protein-protein interaction inhibitor SGI-1027 effectively decreases MYC levels in Osimertinib-resistant NSCLC cell lines. The combination of SGI-1027 with Osimertinib offers synergistic benefits over...
Published: 10/15/2025   |   Inventor(s): Andrey Ivanov, Haian Fu, Shi-Yong Sun, Zhen Chen
Keywords(s): Drug Discovery, Oncology Treatments, Protein and Peptide Therapeutics
Category(s): TechPub Algolia > Therapeutics
Repurposed Receptor Blocker for the Treatment of PTSD
Application Use of neurokinin 3 receptor antagonist, osanetant, for the prevention and treatment of post-traumatic stress disorder (PTSD) and other anxiety disorders. Key Benefits Utilizes a repurposed drug that is safe for human use. Potential to treat specific PTSD symptoms better than antidepressants. Market Summary Post-traumatic stress...
Published: 10/24/2025   |   Inventor(s): Kerry Ressler, Raul Andero Gali
Keywords(s): Neurology and Pain Treatments, Repurposed Drug
Category(s): TechPub Algolia > Therapeutics
Enhanced Delivery and Efficacy of Antisense Drugs via Covalently Linked Nanodisc Scaffolds
Application A synthetic nanodisc (ND) scaffold for delivering antisense oligonucleotides (ASOs) for the treatment of disease. Key Benefits Improved cellular uptake and protein suppression using antisense oligos. Longer ASO half-life compared to other ASO delivery methods. Potential to overcome the delivery and efficacy challenges using ASOs for...
Published: 9/22/2025   |   Inventor(s): Khalid Salaita, Radhika Sharma
Keywords(s): Biomaterials, Cardiology and Vascular Devices, Chemistry, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery, TechPub Algolia > Micro and Nanotechnology
Optimizing the Engineering of CAR-T Cells
Application A method for selecting distinct T cell populations in order to generate more effective CAR-T cells. Key Benefits The proposed invention focuses on selecting the optimal “starting material” for the engineering CAR-T cells. This selection method can be utilized for the development of any and all CAR-T therapies, not limited...
Published: 2/13/2025   |   Inventor(s): Byron Au-Yeung
Keywords(s): Cell Therapy, Oncology Treatments, Production Methods
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Therapeutics
Advancing Lymphatic Endothelial Cell Generation from iPSCs
Application The developed protocol offers a reproducible and scalable method for generating lymphatic endothelial cells (LECs) from induced pluripotent stem cells (iPSCs), addressing critical challenges in the field of lymphatic-related therapies. Key Benefits Reproducible and scalable protocol for generating LECs from iPSCs. Utilizes specific...
Published: 10/3/2025   |   Inventor(s): Katherine Hekman, Katherine Owsiany
Keywords(s): Cell Therapy, Production Methods
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery
Technology for Assessment in Enhancing Memory Measurement in ECT Therapy
Application The Electroconvulsive Cognitive Assessment (ECA) is a 10-minute cognitive exam designed for use during and after Electroconvulsive Therapy (ECT). It focuses on assessing memory deficits associated with ECT, offering a quick and targeted evaluation tool for healthcare professionals. Key Benefits Rapid cognitive assessment in under 10...
Published: 4/3/2025   |   Inventor(s): Adriana Hermida
Keywords(s): Neurology and Pain Treatments, Surveys and Screening Tools
Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Therapeutics
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