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Search Results - cardiology+and+vascular+devices
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Enhanced Delivery and Efficacy of Antisense Drugs via Covalently Linked Nanodisc Scaffolds
Application A synthetic nanodisc (ND) scaffold for delivering antisense oligonucleotides (ASOs) for the treatment of disease. Key Benefits Improved cellular uptake and protein suppression using antisense oligos. Longer ASO half-life compared to other ASO delivery methods. Potential to overcome the delivery and efficacy challenges using ASOs for...
Published: 2/13/2025
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Inventor(s):
Khalid Salaita
,
Radhika Sharma
Keywords(s):
Biomaterials
,
Cardiology and Vascular Devices
,
Chemistry
,
Oncology Treatments
Category(s):
TechPub Algolia > Therapeutics
,
TechPub Algolia > Drug Discovery
,
TechPub Algolia > Micro and Nanotechnology
Automated Software to Quantify Breast Arterial Calcifications from Mammograms
Application Deep learning software for the automated detection and quantification of breast arterial calcifications in screening mammograms. Key Benefits Optimized image segmentation accuracy with improved generalizability towards mammograms with and without BAC presence. Robust ability to quantitate narrow or heavy BAC and/or partial depositions...
Published: 2/13/2025
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Inventor(s):
Hari Trivedi
,
Imon Banerjee
,
William Charles O'Neill
,
Aisha Urooj Khan
,
Theodorus Dapamede
,
Judy Wawira Gichoya
Keywords(s):
Cardiology and Vascular Devices
,
Women's Health
Category(s):
TechPub Algolia > Software
Multimodal Identification of Atrial Fibrillation Recurrence Sites
Application Identifies areas of interest associated with atrial fibrillation recurrences. Key Benefits Identifies sites associated with recurrences for AF patients. Predict AF recurrence risk in patients’ post-catheter ablation. Development of prediction model by extracting features from the surface of interest (SOI). Market Summary Atrial...
Published: 3/6/2025
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Inventor(s):
Abhishek Midya
,
Anant Madabhushi
,
Golnoush Asaeikheybari
,
Mina K. Chung
,
Amogh Hiremath
,
Moore Benjamin Shoemaker
,
Majd A. El-Harasis
,
John Barnard
,
Rod S. Passman
Keywords(s):
Algorithm, AI, and Machine Learning
,
Cardiology and Vascular Devices
,
Medical Imaging (MRI, CT, Radiology)
Category(s):
TechPub Algolia > Diagnostics
System for Assessing Health Severity and Predicting Readmissions
Application A smartphone-based system for monitoring patients to identify and prevent severe cardiac events. Key Benefits A remote monitoring system that uses smartphone data to accurately predict a user’s risk for a severe cardiac event (e.g., heart attack). Tracks the user's movement, location, and physical activity to calculate FDA-accepted...
Published: 3/6/2025
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Inventor(s):
Gari Clifford
,
Amit J. Shah
,
Ayse Cakmak
,
Erik Reinertsen
Keywords(s):
Algorithm, AI, and Machine Learning
,
Cardiology and Vascular Devices
Category(s):
TechPub Algolia > Diagnostics
,
TechPub Algolia > Software
Drug Screening System for Cardioprotection
Application A high throughput screening assay for developing therapies to protect from drug and alcohol-induced cardiotoxicity. Key Benefits A cardiovascular stem-cell-based screening assay that can identify drugs that protect the heart from toxic medications and alcohol. Preliminary data in the laboratory show the system is clinically relevant...
Published: 2/13/2025
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Inventor(s):
Chunhui Xu
,
Antonio Rampoldi
,
Yuhong Du
Keywords(s):
Cardiology and Vascular Devices
,
Screening Assays
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
,
TechPub Algolia > Drug Discovery
ONC201 for the Treatment of Vascular Aneurysms
Application A repurposed therapeutic for the preventative and treatment of aneurysms. Key Benefits A repurposed cancer drug that targets cells known to be damaged during the progression of an aneurysm. The drug has been tested within an animal model of aortic aneurysms, where it prevented the severe complications of the disease and protected the...
Published: 2/28/2025
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Inventor(s):
Alejandra Maria San Martin
Keywords(s):
Cardiology and Vascular Devices
,
Repurposed Drug
Category(s):
TechPub Algolia > Drug Discovery
Engineered Biomaterials for Vascular Grafts
Application A biomaterial to create grafts for treating babies with congenital heart diseases. Key Benefits A biocompatible material that can be used to reroute blood within the body. Experimental data in animals show the material is biocompatible with no clots, thrombus, or adverse immune reactions. Potential to be used in other cardiovascular...
Published: 2/13/2025
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Inventor(s):
Saimuralidhar (Murali) Padala
,
Jahnavi Mudigonda
Keywords(s):
Biomaterials
,
Cardiology and Vascular Devices
,
Pediatrics
Category(s):
TechPub Algolia > Non-Therapeutics
Automated Breast Arterial Calcifications Segmentation and Quantification on Mammograms Using Deep Learning
Application Software for the quantification of breast arterial calcifications on routine mammograms to be used for risk stratification for cardiovascular outcomes. Key Benefits Optimized image segmentation accuracy with reduced software complexity. Integrated calcium scoring. Screens patients who would not normally be indicated for cardiac...
Published: 2/13/2025
|
Inventor(s):
Hari Trivedi
,
Imon Banerjee
,
William Charles O'Neill
,
Xiaoyuan Guo
Keywords(s):
Algorithm, AI, and Machine Learning
,
Cardiology and Vascular Devices
,
Medical Imaging (MRI, CT, Radiology)
,
Women's Health
Category(s):
TechPub Algolia > Software
Small Molecules for Development of Cardiac Chamber-Specific Myocytes
Application Small molecule activators and inhibitors of retinoic acid (RA) to create chamber-specific myocytes from pluripotent stem cells without cell sorting. Key Benefits Produces highly-enriched, subtype-specific populations of cardiac myocytes. Eliminates need for cell-sorting. Does not require transgenic changes to the human stem cells. Market...
Published: 2/28/2025
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Inventor(s):
Hee Cheol Cho
,
Pengcheng Han
Keywords(s):
Cardiology and Vascular Devices
,
Cell Therapy
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
,
TechPub Algolia > Drug Discovery
Reprogramming of Fibroblasts toward a Three-Dimensional Vascularized Cardiomimetic Tissue (CMT)
Application Fibroblasts reprogrammed into tissue-like patch including functional cardiomyocyte, endothelial, smooth muscle and pericyte cells for treatment of cardiac diseases. Key Benefits Enables simultaneous reprogramming of multi-lineage cells including cardiomyocytes and endothelial cells Increases expression of cardioprotective paracrine...
Published: 2/13/2025
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Inventor(s):
Young-Sup Yoon
,
Jaeyeaon Cho
Keywords(s):
Cardiology and Vascular Devices
,
Cell Therapy
,
Platform
,
Regenerative Medicine
Category(s):
TechPub Algolia > Therapeutics
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