Search Results - rafi+ahmed

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Vaccines and Antibody Therapeutics for HPV-related Cancers

Application Treatment and prevention of HPV-induced malignancies. Key Benefits Identification of a protein expressed in a large number of HPV-induced cancers. Antibodies have been generated that bind to the protein and potentially elicit an immune response to the cancer cells. The antibodies can be used to develop new treatments and vaccines...

Published: 10/28/2024 | Inventor(s): Rafi Ahmed, Andreas Wieland

Keywords(s): Biologic, Microbiology/Infectious Diseases, Oncology

Category(s): TechPub Algolia > Therapeutics

Tumor Specific CD8 T Cell TCR Sequences of HPV-Positive Head and Neck Tumors

Application HPV-specific CD8 TCR sequences for the treatment of HPV-positive head and neck cancer by adoptive cell therapy. Key Benefits HPV tumor antigen set is specific for HPV-positive head and neck cancer. Targeting of ‘non-classical’ HPV antigens E2 and E5. Potential to synergize and complement HPV E6/7-specific TCR therapies...

Published: 10/17/2024 | Inventor(s): Rafi Ahmed, Christiane Eberhardt, Andreas Wieland

Keywords(s): Cell/Gene Therapy, Oncology

Category(s): TechPub Algolia > Therapeutics

Isolation of Therapeutic cells and Framework for Adoptive Cell Therapies

Application Isolation of therapeutic cells and framework for adoptive cell therapies based around stem-like chronic memory CD8 T cells that may be paired with PD-1 blockade. Key Benefits Persistent cell survival and therapeutic efficacy following rechallenge with chronic viral infection and cancer. Strong co-treatment potential with PD-1...

Published: 10/17/2024 | Inventor(s): Rafi Ahmed, Daniel Chang

Keywords(s): Cell/Gene Therapy

Category(s): TechPub Algolia > Therapeutics

Serological Test for SARS-CoV-2

Application Clinical assay for detecting SARS-CoV-2 neutralizing antibodies. Key Benefits Highly specific and sensitive. Fewer false positives than commercially available tests. Market Summary SARS-CoV-2 is currently causing a devastating pandemic and there is a pressing need to understand the dynamics, specificity, and neutralizing...

Published: 7/30/2024 | Inventor(s): Rafi Ahmed, Mehul Suthar, John Roback, Jens Wrammert, Robert Kauffman

Keywords(s): Assay, COVID19, Microbiology/Infectious Diseases, Vaccine

Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Drug Discovery, TechPub Algolia > Micro and Nanotechnology

Antibody Therapy for Varicella Zoster Virus

Application Human monoclonal antibodies for the treatment of varicella zoster virus (VZV). Key Benefits Human monoclonal antibodies can limit the spread of VZV. gH-specific antibodies are complement-independent. Market Summary Varicella Zoster Virus (VZV) causes varicella, more commonly known as chickenpox. Once the illness resolves, the virus...

Published: 10/28/2024 | Inventor(s): Rafi Ahmed, Nicole Sullivan

Keywords(s): Antibody, Microbiology/Infectious Diseases

Category(s): TechPub Algolia > Therapeutics

Promising Antibodies Target Virus Glycoprotein for Vaccination and Therapy

ApplicationAntibodies that bind and neutralize Ebola virus glycoprotein (GP) for use in vaccination or treatment of Ebola virus disease.Key BenefitsHigher binding affinity for Ebola virus GP than closest competitor.Can be used prophylactically or for treatment of Ebola virus disease.Market SummaryThe Ebola virus is an RNA virus with a membrane composed...

Published: 8/22/2024 | Inventor(s): Rafi Ahmed, Carl Davis, Erica Ollmann Saphire

Keywords(s): Antibody, Microbiology/Infectious Diseases

Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Vaccines

Genetic Mutation in Immune Cells for Infectious Disease and Cancer Therapy

Application Conditional epigenetic mutation in CD8+ memory T cells as potential cell therapy for chronic viral infection and personalized cancer treatment. Key Benefits Blocks DNA methylation in T cells, prolonging the life and enhancing the function of these cells. Results in faster CD62L re-expression during effector to memory cell conversion. Delays...

Published: 10/28/2024 | Inventor(s): Benjamin Youngblood, Rafi Ahmed

Keywords(s): Cell/Gene Therapy, Microbiology/Infectious Diseases, Oncology

Category(s): TechPub Algolia > Therapeutics

Cross-Reactive Antibodies Against Influenza Virus

Application Human recombinant antibodies against influenza, including H1N1, for the development of diagnostic tests and universal flu vaccines. Key Benefits Broadly protective antibodies against multiple influenza strains Market Summary Influenza spreads swiftly and globally, causing some of the most severe pandemics in the last century. Each year,...

Published: 7/30/2024 | Inventor(s): Rafi Ahmed, Patrick Wilson, Jens Wrammert

Keywords(s): Antibody, Microbiology/Infectious Diseases

Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Research Tools, TechPub Algolia > Therapeutics