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Search Results - technology+classifications+%3e+medical
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A Vaccine Technology for Preventing Clostridioides difficile Infection Using Cell Wall Protein 2 (CWP 2)
Advantages: A recombinant Cwp2 protein that induces strong IgG and IgA antibody response in animal models. Decrease levels of C. difficile spores and toxins in feces and decrease mortality rates in immunized mice. Anti-Cwp2 antibodies delay the binding of C. difficile vegetative cells to human gut epithelial cells and prevent bacterial colonization....
Published: 9/17/2024
|
Inventor(s):
Xingmin Sun
,
Shaohui Wang
Keywords(s):
Vaccines
Category(s):
Technology Classifications > Medical
> Pharmaceuticals
,
Technology Classifications > Medical
,
Technology Classifications > Medical
> Biotechnology
Drug-Induced Activation of the Reelin Signaling System
Advantages: Small, soluble drug with therapeutic potential Independent Reelin signaling pathway activation More able to pass through the BBB than Reelin Summary: The Reelin signaling pathway is an essential component of the developing and adult central nervous systems. The signaling cascade assists with the regulation of developing neurons...
Published: 7/24/2024
|
Inventor(s):
Edwin Weeber
,
Melinda Peters
,
Qingyou Li
,
Hana Soueidan
Keywords(s):
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical
> Neuroscience
Topical Formulations for Treatment of Hypergranulation Tissue
Advantages: Inexpensive and easily manufactured. Fast acting with improvement in the first 72 hours after treatment. No adverse side effects. Summary: Hypergranulation tissue is an excessive growth of granulation tissue in a wound and is a problem that can be encountered in burn care when wounds take a significant time to heal at burn sites...
Published: 9/3/2024
|
Inventor(s):
Wlliam West
Keywords(s):
Dermatology / Skin
,
Wound and Tissue Healing
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical
> Therapeutics
Regulated Delivery of Antibiotic and Antifungal Drugs Via Controlled Degradable Chondroitin Sulfate Particles
Advantages: Novel synthesis of Chondroitin sulfate (CS) particles for encapsulation of antibiotic and antifungal drugs. Synthesis can be fine-tuned to produced non-degradable, slightly degradable, and completely degradable CS drug carriers, for a variety of therapeutic applications. CS particles were successfully tested for encapsulation...
Published: 5/14/2024
|
Inventor(s):
NURETTIN SAHINER
,
Ramesh Ayyala
Keywords(s):
Drug Delivery and Nanomedicine
,
Pharmaceuticals
Category(s):
Technology Classifications > Medical
> Cell & Tissue Engineering
,
Technology Classifications > Medical
> Infectious Diseases
,
Technology Classifications > Medical
> Therapeutics
,
Technology Classifications > Medical
Fabrication of Cyclodextrins Particles and Super Porous Cryogels for Solubilization and Extended Delivery of Multiple Hydrophobic/lipophilic Drugs and Toxic Chemicals
Advantages: Enhanced Therapeutic Effectiveness: It improves the efficacy of drug treatments by enhancing solubility and bioavailability. Customizable Drug Delivery: Offers tailored drug release profiles and the ability to deliver multiple drugs simultaneously. Cross-Industry Applicability: Finds applications in pharmaceuticals, environmental...
Published: 4/17/2024
|
Inventor(s):
NURETTIN SAHINER
,
Manoj Ram
,
Ramesh Ayyala
Keywords(s):
Drug Delivery Systems
Category(s):
Technology Classifications > Engineering > Electrical Engineering
,
Technology Classifications > Medical
,
Technology Classifications > Medical
> Ophthalmology
Use of Chemokine Receptor Antagonists for Fluid Resuscitation
Advantages: Reduces amount of fluid required for resuscitation Reduces risk of complications New direction in critical care Summary: Our research focuses on improving the treatment of critically ill patients, especially those undergoing major surgery or suffering from conditions like severe burns, trauma, hemorrhage, or sepsis. Adequate...
Published: 9/21/2023
|
Inventor(s):
Anthony DeSantis
,
Xianlong Gao
,
Matthias Majetschak
Keywords(s):
Critical Care / Trauma
,
Medical Pharmaceuticals
,
Therapeutics
Category(s):
Technology Classifications > Medical
Dual Function Hybrid Nanoparticles For Gene Therapy Of Neurological Diseases
Advantages: Novel hybrid nanoparticles fabricated to carry a dual payload. Efficient encapsulation of payload, while minimizing potential cell cytotoxicity. Can navigate the blood-brain barrier, facilitating precise targeting. Demonstrates anti-inflammatory properties in addition to gene-silencing capabilities. Summary: Nanocarriers...
Published: 6/11/2024
|
Inventor(s):
Oksana Fihurka
,
Vasyl Sava
,
Juan Sanchez-Ramos
Keywords(s):
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical
> Neuroscience
Artificial Patient Replica Device for Physical Therapy Training
Advantages: Quantitative and objective assessment device to track a patient’s functional progress. Real-time personalized feedback for optimized treatment. Standardized and consistent evaluations across therapists and sessions. Summary: Physical therapists (PTs) assist patients in completing a variety of rehabilitation tasks such...
Published: 6/11/2024
|
Inventor(s):
Benjamin Rigsby
,
Seok Kim
,
Kyle Reed
Keywords(s):
Simulation Training Aid
Category(s):
Technology Classifications > Medical
Microbiome Based Precision Nutrition Model
Advantages: By identifying suitable diets that enhance beneficial bacteria and metabolic activities, the research can potentially help individuals address gut-related issues and reduce conditions like leaky gut and inflammation. By understanding the unique composition of the gut microbiota and its response to different dietary factors, personalized...
Published: 9/25/2023
|
Inventor(s):
Hariom Yadav
,
Shalini Jain
Keywords(s):
Gastrointestinal / Digestive Health
,
Microbiome
Category(s):
Technology Classifications > Medical
> Cell & Tissue Engineering
,
Technology Classifications > Medical
,
Technology Classifications > Medical
> Neuroscience
UBE3A Gene Therapy for the Treatment of Tauopathies
Advantages: Reduction in Pathology Improved Memory and Cognitive Function Targeted Delivery and Brain-wide Distribution Business Summary: Alzheimer’s disease (AD) is a neurodegenerative disease that involves the accumulation of A-Beta proteins and Tau proteins within the brain and leads to cognitive impairments. The accumulation of these...
Published: 9/26/2023
|
Inventor(s):
Jazmin Pena
,
Kevin Nash
Keywords(s):
Medical Diagnostics
,
Neurodegenerative Diseases
,
Neuroscience
,
Therapeutics
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical
> Neuroscience
,
Technology Classifications > Medical
> Biomedical Engineering
,
Technology Classifications > Medical
> Biotechnology
,
Technology Classifications > Medical
> Medical Diagnostics
,
Technology Classifications > Medical
> Therapeutics
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