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Suppression of Therapeutic Escape in Breast Cancer by BTK Inhibition

This technology offers the potential of new and novel cancer treatments based on various inhibitors of protein tyrosine kinases Background: Genes that regulate extracellular growth, differentiation, and developmental signals are commonly mutated in cancers. Protein tyrosine kinases (PTKs) mediate the reversible process of tyrosine phosphorylation,...

Published: 9/5/2024 | Inventor(s): Douglas Conklin, Xianhui Wang

Keywords(s): breast cancer, cancer, Technologies, therapeutic targets

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Therapeutics and Vaccines

In Vitro Dental Plaque Culture Model for Biofilm Structural Analyses

This technology provides a valuable tool for studying the molecular and cellular basis of dental plaque-mediated diseases. Background: In vitro oral microcosm communities, seeded with mixed communities of human dental plaque, have proven to be essential tools for studying the taxonomic composition of dental plaque communities and changes in community...

Published: 9/5/2024 | Inventor(s): Alex Valm

Keywords(s): biofilm control, dental, dental materials, structural biology, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents

Enduraphin

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Published: 6/7/2024 | Inventor(s):

Keywords(s): Startups

Category(s): Technology Classifications > Healthcare

Powered Leg Prosthesis with a Unified Joint Actuator Design (Knee & Ankle)

Problem: Existing lower-limb prostheses are mostly unpowered, i.e., cannot supply power to support users’ walking. As such, amputees fitted with unpowered prostheses suffer from many problems such as unnatural walking and increase energy consumption. Although powered prostheses have appeared on the market, they are still heavy and expensive....

Published: 4/17/2024 | Inventor(s): Xiangrong Shen, Md Rayhan Afsar, Md Rejwanul Haque

Keywords(s):

Category(s): Technology Classifications > Healthcare, Technology Classifications > Lifestyle & Leisure

Excelsior Biofilms, LLC

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Published: 3/12/2024 | Inventor(s): Binghamton University

Keywords(s): Startups

Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Binghamton University

miR Scientific, LLC

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Published: 3/11/2024 | Inventor(s): University at Albany

Keywords(s): Startups

Category(s): Technology Classifications > Healthcare, Technology Classifications > Medical Devices, Campus > University at Albany

Human-Derived ECM Hydrogels Produced from Organoids

The Problem: Hydrogel-based tissue scaffolds are designed to mimic native extracellular matrix (ECM) to provide the framework for cell and tissue regeneration for regenerative medicine or research involving human cells. Human ECM is extremely complex, and difficult to reproduce. Current conventional tissue scaffolds are primarily produced from animal...

Published: 1/30/2024 | Inventor(s): Alexandra Avera, Yonghyun Kim

Keywords(s):

Category(s): Technology Classifications > Healthcare, Technology Classifications > Manufacturing

Scalable Biomanufacturing of Tumor Organoids

The Problem: Tumor organoids are miniaturized models of simplified tumor tissue. This new generation of cancer modeling is highly useful for observing cell-to-cell interactions, cell-to-matrix interactions, and cell differentiation. However, the current process for creating organoids is generated by tissue isolated from animals or humans, does not...

Published: 1/30/2024 | Inventor(s): Alexandra Avera, Seung Jo Park, Yonghyun Kim

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Healthcare, Technology Classifications > Manufacturing

Nucleic Acids that Encode Sodium Channels

Provides a method for screening compounds for use as anti-arrhythmic agents and other medications using mutant mammalian voltage-gated sodium channel subunit. Background: Mammalian voltage-gated sodium channels are pore-forming membrane proteins responsible for the initiation and propagation of actions in nerve, skeletal muscle, and heart cells. The...

Published: 1/29/2024 | Inventor(s): Sho-Ya Wang

Keywords(s):

Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Technology Classifications > Drug Delivery

Laser Ablation Direct Analysis in Real Time-Imaging Mass Spectrometry (LADI-MS)

Offers the potential of real-time small-sample analysis for a very large variety of applications. Background: Real Time Imaging Mass Spectrometry (RTMS) is a method for analyzing and identifying biological samples in real time. RTMS can be used in an extremely broad variety of applications, involving chemistry, biochemistry, food sciences, and medicine....

Published: 1/23/2024 | Inventor(s): Rabi Musah

Keywords(s): analytical chemistry, Biomarker discovery, chemistry, forensic testing, image acquisition, imaging, life sciences, Mass spectrometry imaging, medical imaging, Natural products, Phytochemistry, Small-molecule profiling, Small-molecule spatial distribution mapping, Species discrimination, Species identification, Technologies, Tissue analysis, wood anatomy, wood science

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